Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              19     665
NP_444254                                                              19     665
NP_444253                                                              19     665
NP_444255                                                              19     665
XP_005247551                                                           19     665
XP_005247550                                                           19     665
XP_006713712                                                           19     665
XP_005247549                                                           19     665
NP_001138890                                                           17    3301
XP_006724234                                                           17    3301
XP_005261462                                                           17    3301
NP_004506                                                              16    5631
NP_001254738                                                           16    5631
NP_149974                                                              16    5631
NP_004420                                                              16    7355
NP_004841                                                              15    9605
NP_003571                                                              15    9605
NP_001138244                                                           15    9605
XP_005246247                                                           15    9605
>NP_444256
          Length = 1794

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TESDATVK 8
            TESDATVK
Sbjct: 1147 TESDATVK 1154
>NP_444254
          Length = 1845

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TESDATVK 8
            TESDATVK
Sbjct: 1147 TESDATVK 1154
>NP_444253
          Length = 1914

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TESDATVK 8
            TESDATVK
Sbjct: 1216 TESDATVK 1223
>NP_444255
          Length = 1863

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TESDATVK 8
            TESDATVK
Sbjct: 1216 TESDATVK 1223
>XP_005247551
          Length = 1855

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TESDATVK 8
            TESDATVK
Sbjct: 1157 TESDATVK 1164
>XP_005247550
          Length = 1856

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TESDATVK 8
            TESDATVK
Sbjct: 1226 TESDATVK 1233
>XP_006713712
          Length = 1923

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TESDATVK 8
            TESDATVK
Sbjct: 1226 TESDATVK 1233
>XP_005247549
          Length = 1924

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TESDATVK 8
            TESDATVK
Sbjct: 1226 TESDATVK 1233
>NP_001138890
          Length = 2481

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    TESDATVK 8
            TE+D+TVK
Sbjct: 2141 TETDSTVK 2148
>XP_006724234
          Length = 2363

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    TESDATVK 8
            TE+D+TVK
Sbjct: 2023 TETDSTVK 2030
>XP_005261462
          Length = 2473

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    TESDATVK 8
            TE+D+TVK
Sbjct: 2133 TETDSTVK 2140
>NP_004506
          Length = 390

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TESDATVKM 9
           + SDATVK+
Sbjct: 167 SSSDATVKI 175
>NP_001254738
          Length = 352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TESDATVKM 9
           + SDATVK+
Sbjct: 129 SSSDATVKI 137
>NP_149974
          Length = 484

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TESDATVKM 9
           TE+ AT++M
Sbjct: 135 TEAQATIRM 143
>NP_004420
          Length = 346

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ESDATVKM 9
           E+D TVKM
Sbjct: 184 EADNTVKM 191
>NP_004841
          Length = 1388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   TESDATV 7
           TE DAT+
Sbjct: 962 TEKDATI 968
>NP_003571
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TESDATVKM 9
           T  D+T+KM
Sbjct: 648 TSQDSTLKM 656
>NP_001138244
          Length = 948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TESDATVKM 9
           T  D+T+KM
Sbjct: 679 TSQDSTLKM 687
>XP_005246247
          Length = 1417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   TESDATV 7
           TE DAT+
Sbjct: 962 TEKDATI 968
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.293    0.103    0.237 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 418,990
Number of extensions: 690
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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