Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1135
NP_671714                                                              18    1135
XP_006715890                                                           18    1135
XP_005250160                                                           18    1135
XP_005250159                                                           18    1135
NP_036367                                                              17    3301
XP_005265029                                                           17    3301
XP_005265028                                                           17    3301
XP_005265027                                                           17    3301
XP_005265026                                                           17    3301
XP_005265025                                                           17    3301
XP_005265024                                                           17    3301
XP_006713097                                                           17    3301
NP_001171940                                                           16    5631
NP_689512                                                              16    5631
NP_054777                                                              16    5631
XP_005261969                                                           16    5631
NP_000072                                                              16    7355
XP_005273087                                                           16    7355
XP_006711794                                                           16    7355
XP_005273086                                                           16    7355
XP_005273085                                                           16    7355
XP_005273084                                                           16    7355
NP_036603                                                              15    9605
>NP_005742
          Length = 3907

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TELSQRLV 8
            TELSQRLV
Sbjct: 1819 TELSQRLV 1826
>NP_671714
          Length = 3899

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TELSQRLV 8
            TELSQRLV
Sbjct: 1819 TELSQRLV 1826
>XP_006715890
          Length = 3860

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TELSQRLV 8
            TELSQRLV
Sbjct: 1772 TELSQRLV 1779
>XP_005250160
          Length = 3939

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TELSQRLV 8
            TELSQRLV
Sbjct: 1851 TELSQRLV 1858
>XP_005250159
          Length = 3952

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TELSQRLV 8
            TELSQRLV
Sbjct: 1851 TELSQRLV 1858
>NP_036367
          Length = 1279

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TELSQRLVM 9
           T L+QRL+M
Sbjct: 513 TRLAQRLIM 521
>XP_005265029
          Length = 886

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TELSQRLVM 9
           T L+QRL+M
Sbjct: 121 TRLAQRLIM 129
>XP_005265028
          Length = 887

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TELSQRLVM 9
           T L+QRL+M
Sbjct: 121 TRLAQRLIM 129
>XP_005265027
          Length = 887

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TELSQRLVM 9
           T L+QRL+M
Sbjct: 121 TRLAQRLIM 129
>XP_005265026
          Length = 1023

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TELSQRLVM 9
           T L+QRL+M
Sbjct: 258 TRLAQRLIM 266
>XP_005265025
          Length = 1024

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TELSQRLVM 9
           T L+QRL+M
Sbjct: 258 TRLAQRLIM 266
>XP_005265024
          Length = 1278

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TELSQRLVM 9
           T L+QRL+M
Sbjct: 513 TRLAQRLIM 521
>XP_006713097
          Length = 1279

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TELSQRLVM 9
           T L+QRL+M
Sbjct: 513 TRLAQRLIM 521
>NP_001171940
          Length = 606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TELSQRL 7
           TELSQR+
Sbjct: 490 TELSQRI 496
>NP_689512
          Length = 605

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TELSQRL 7
           TELSQR+
Sbjct: 489 TELSQRI 495
>NP_054777
          Length = 423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  TELSQRL 7
          TE+SQRL
Sbjct: 77 TEMSQRL 83
>XP_005261969
          Length = 579

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TELSQRL 7
           TELSQR+
Sbjct: 463 TELSQRI 469
>NP_000072
          Length = 3801

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TELSQRL 7
            TEL+QRL
Sbjct: 2637 TELAQRL 2643
>XP_005273087
          Length = 2788

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TELSQRL 7
            TEL+QRL
Sbjct: 2637 TELAQRL 2643
>XP_006711794
          Length = 3022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TELSQRL 7
            TEL+QRL
Sbjct: 1858 TELAQRL 1864
>XP_005273086
          Length = 3264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TELSQRL 7
            TEL+QRL
Sbjct: 2637 TELAQRL 2643
>XP_005273085
          Length = 3755

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TELSQRL 7
            TEL+QRL
Sbjct: 2591 TELAQRL 2597
>XP_005273084
          Length = 3801

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TELSQRL 7
            TEL+QRL
Sbjct: 2637 TELAQRL 2643
>NP_036603
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TELSQR 6
           TELSQR
Sbjct: 775 TELSQR 780
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.127    0.293 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 297,145
Number of extensions: 420
Number of successful extensions: 24
Number of sequences better than 10000.0: 24
Number of HSP's gapped: 24
Number of HSP's successfully gapped: 24
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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