Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_076955                                                              19     665
NP_006651                                                              17    2528
XP_005260350                                                           17    4312
XP_006723770                                                           17    4312
NP_542406                                                              17    4312
NP_001073291                                                           16    5631
NP_000417                                                              16    5631
NP_001138883                                                           16    5631
XP_005267039                                                           16    5631
XP_005267038                                                           16    5631
XP_006714236                                                           16    5631
XP_005262948                                                           16    5631
XP_006714235                                                           16    5631
NP_689988                                                              16    5631
NP_620410                                                              16    5631
NP_631960                                                              16    5631
NP_997320                                                              16    7355
XP_005253612                                                           16    7355
NP_065080                                                              15    9605
NP_001263308                                                           15    9605
NP_001263307                                                           15    9605
NP_001245245                                                           15    9605
NP_060568                                                              15    9605
NP_001245244                                                           15    9605
NP_620155                                                              15    9605
NP_065937                                                              15    9605
NP_001157936                                                           15    9605
XP_005271698                                                           15    9605
XP_005271696                                                           15    9605
XP_005271695                                                           15    9605
XP_005271694                                                           15    9605
XP_005271693                                                           15    9605
XP_005271690                                                           15    9605
XP_005271689                                                           15    9605
XP_005271688                                                           15    9605
XP_005271687                                                           15    9605
XP_006717791                                                           15    9605
XP_006717790                                                           15    9605
XP_006717789                                                           15    9605
XP_005247237                                                           15    9605
XP_006713587                                                           15    9605
XP_005247233                                                           15    9605
XP_006713586                                                           15    9605
XP_006713270                                                           15    9605
XP_006712770                                                           15    9605
XP_006712325                                                           15    9605
>NP_076955
          Length = 102

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  TEKTNILL 8
          TEKTNILL
Sbjct: 49 TEKTNILL 56
>NP_006651
          Length = 633

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   EKTNILLL 9
           EK+NILLL
Sbjct: 285 EKSNILLL 292
>XP_005260350
          Length = 289

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EKTNILLL 9
          EKT ILLL
Sbjct: 13 EKTGILLL 20
>XP_006723770
          Length = 350

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   EKTNILLL 9
           EKT ILLL
Sbjct: 103 EKTGILLL 110
>NP_542406
          Length = 379

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   EKTNILLL 9
           EKT ILLL
Sbjct: 103 EKTGILLL 110
>NP_001073291
          Length = 3118

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKTNILLL 9
           E TN+LLL
Sbjct: 648 EHTNVLLL 655
>NP_000417
          Length = 3122

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKTNILLL 9
           E TN+LLL
Sbjct: 648 EHTNVLLL 655
>NP_001138883
          Length = 796

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KTNILLL 9
           KTNILL+
Sbjct: 538 KTNILLI 544
>XP_005267039
          Length = 3206

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKTNILLL 9
           E TN+LLL
Sbjct: 648 EHTNVLLL 655
>XP_005267038
          Length = 3210

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKTNILLL 9
           E TN+LLL
Sbjct: 648 EHTNVLLL 655
>XP_006714236
          Length = 771

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KTNILLL 9
           KTNILL+
Sbjct: 505 KTNILLI 511
>XP_005262948
          Length = 836

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KTNILLL 9
           KTNILL+
Sbjct: 575 KTNILLI 581
>XP_006714235
          Length = 841

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KTNILLL 9
           KTNILL+
Sbjct: 575 KTNILLI 581
>NP_689988
          Length = 833

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KTNILLL 9
           KTNILL+
Sbjct: 575 KTNILLI 581
>NP_620410
          Length = 241

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TEKTNILLL 9
          +EKTN+ LL
Sbjct: 87 SEKTNLSLL 95
>NP_631960
          Length = 185

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TEKTNILLL 9
          +EKTN+ LL
Sbjct: 87 SEKTNLSLL 95
>NP_997320
          Length = 4471

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    TEKTNILLL 9
            +E+TNI+L+
Sbjct: 2473 SEETNIVLM 2481
>XP_005253612
          Length = 4589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    TEKTNILLL 9
            +E+TNI+L+
Sbjct: 2591 SEETNIVLM 2599
>NP_065080
          Length = 299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TEKTNILLL 9
          T  TN+LLL
Sbjct: 76 TAYTNVLLL 84
>NP_001263308
          Length = 256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TEKTNILLL 9
          T  TN+LLL
Sbjct: 72 TAYTNVLLL 80
>NP_001263307
          Length = 282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TEKTNILLL 9
          T  TN+LLL
Sbjct: 59 TAYTNVLLL 67
>NP_001245245
          Length = 883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TEKTNILL 8
           TE+ N+LL
Sbjct: 731 TEQANVLL 738
>NP_060568
          Length = 883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TEKTNILL 8
           TE+ N+LL
Sbjct: 731 TEQANVLL 738
>NP_001245244
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TEKTNILL 8
           TE+ N+LL
Sbjct: 762 TEQANVLL 769
>NP_620155
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  KTNILL 8
          KTNILL
Sbjct: 65 KTNILL 70
>NP_065937
          Length = 1077

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TEKTNILLL 9
           TEK NI+ +
Sbjct: 207 TEKRNIMFM 215
>NP_001157936
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  KTNILL 8
          KTNILL
Sbjct: 65 KTNILL 70
>XP_005271698
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  TEKTNILLL 9
          TEK NI+ +
Sbjct: 82 TEKRNIMFM 90
>XP_005271696
          Length = 1045

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TEKTNILLL 9
           TEK NI+ +
Sbjct: 207 TEKRNIMFM 215
>XP_005271695
          Length = 1046

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TEKTNILLL 9
           TEK NI+ +
Sbjct: 207 TEKRNIMFM 215
>XP_005271694
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TEKTNILLL 9
           TEK NI+ +
Sbjct: 207 TEKRNIMFM 215
>XP_005271693
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TEKTNILLL 9
           TEK NI+ +
Sbjct: 207 TEKRNIMFM 215
>XP_005271690
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TEKTNILLL 9
           TEK NI+ +
Sbjct: 185 TEKRNIMFM 193
>XP_005271689
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TEKTNILLL 9
           TEK NI+ +
Sbjct: 204 TEKRNIMFM 212
>XP_005271688
          Length = 1139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TEKTNILLL 9
           TEK NI+ +
Sbjct: 207 TEKRNIMFM 215
>XP_005271687
          Length = 1140

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TEKTNILLL 9
           TEK NI+ +
Sbjct: 207 TEKRNIMFM 215
>XP_006717791
          Length = 1210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  EKTNILLL 9
          +KTNIL L
Sbjct: 19 KKTNILCL 26
>XP_006717790
          Length = 1255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  EKTNILLL 9
          +KTNIL L
Sbjct: 19 KKTNILCL 26
>XP_006717789
          Length = 1261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  EKTNILLL 9
          +KTNIL L
Sbjct: 19 KKTNILCL 26
>XP_005247237
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TEKTNILL 8
           TE+ N+LL
Sbjct: 561 TEQANVLL 568
>XP_006713587
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TEKTNILL 8
           TE+ N+LL
Sbjct: 762 TEQANVLL 769
>XP_005247233
          Length = 927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TEKTNILL 8
           TE+ N+LL
Sbjct: 731 TEQANVLL 738
>XP_006713586
          Length = 958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TEKTNILL 8
           TE+ N+LL
Sbjct: 762 TEQANVLL 769
>XP_006713270
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TEKTNILLL 9
           T  TN+LLL
Sbjct: 133 TAYTNVLLL 141
>XP_006712770
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  KTNILL 8
          KTNILL
Sbjct: 65 KTNILL 70
>XP_006712325
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  KTNILL 8
          KTNILL
Sbjct: 65 KTNILL 70
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.134    0.323 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 427,315
Number of extensions: 760
Number of successful extensions: 46
Number of sequences better than 10000.0: 46
Number of HSP's gapped: 46
Number of HSP's successfully gapped: 46
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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