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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001121782                                                           16    7355
NP_004675                                                              16    7355
NP_542166                                                              16    7355
NP_056357                                                              16    7355
NP_001245135                                                           15    9605
NP_001245136                                                           15    9605
NP_005419                                                              15    9605
NP_003451                                                              15    9605
NP_001268451                                                           15    9605
NP_001268449                                                           15    9605
NP_877954                                                              15    9605
NP_001268450                                                           15    9605
NP_115874                                                              15    9605
NP_001277033                                                           15    9605
XP_005255619                                                           15    9605
NP_001005278                                                           15    9605
NP_001004454                                                           15    9605
NP_003688                                                              15    9605
NP_001005234                                                           15    9605

>NP_001121782
          Length = 664

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TEKRTISSA 9
           TE++T+S A
Sbjct: 311 TEEKTVSEA 319



>NP_004675
          Length = 664

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TEKRTISSA 9
           TE++T+S A
Sbjct: 311 TEEKTVSEA 319



>NP_542166
          Length = 1272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  TEKRTISS 8
          +E+RT+SS
Sbjct: 26 SERRTVSS 33



>NP_056357
          Length = 1272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  TEKRTISS 8
          +E+RT+SS
Sbjct: 26 SERRTVSS 33



>NP_001245135
          Length = 823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   EKRTIS 7
           EKRTIS
Sbjct: 747 EKRTIS 752



>NP_001245136
          Length = 813

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   EKRTIS 7
           EKRTIS
Sbjct: 737 EKRTIS 742



>NP_005419
          Length = 845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   EKRTIS 7
           EKRTIS
Sbjct: 769 EKRTIS 774



>NP_003451
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EKRTISS 8
           EKRT+S+
Sbjct: 738 EKRTVSN 744



>NP_001268451
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EKRTISSA 9
           ++RTISSA
Sbjct: 569 KQRTISSA 576



>NP_001268449
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EKRTISSA 9
           ++RTISSA
Sbjct: 616 KQRTISSA 623



>NP_877954
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EKRTISSA 9
           ++RTISSA
Sbjct: 600 KQRTISSA 607



>NP_001268450
          Length = 880

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EKRTISSA 9
           ++RTISSA
Sbjct: 656 KQRTISSA 663



>NP_115874
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EKRTISSA 9
           ++RTISSA
Sbjct: 616 KQRTISSA 623



>NP_001277033
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EKRTISS 8
           EKRT+S+
Sbjct: 729 EKRTVSN 735



>XP_005255619
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EKRTISS 8
           EKRT+S+
Sbjct: 827 EKRTVSN 833



>NP_001005278
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TEKRTISSA 9
          +EK+TIS A
Sbjct: 87 SEKKTISFA 95



>NP_001004454
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TEKRTISSA 9
          +EK+TIS A
Sbjct: 88 SEKKTISYA 96



>NP_003688
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TEKRTISSA 9
          +EK+TIS A
Sbjct: 87 SEKKTISFA 95



>NP_001005234
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TEKRTISSA 9
          +EK+TIS A
Sbjct: 87 SEKKTISYA 95



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.290    0.100    0.219 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 413,944
Number of extensions: 445
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)