Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1135
XP_006716142                                                           18    1135
XP_005250088                                                           18    1135
XP_006716141                                                           18    1135
XP_005250085                                                           18    1135
XP_006716140                                                           18    1135
XP_005250084                                                           18    1135
XP_005250083                                                           18    1135
XP_005250082                                                           18    1135
NP_001005163                                                           17    3301
NP_001092880                                                           16    5631
NP_001092881                                                           16    5631
NP_055525                                                              16    5631
NP_001171656                                                           16    5631
XP_005247977                                                           15    9605
NP_055594                                                              15    9605
NP_001005289                                                           15    9605
>NP_733751
          Length = 4911

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TDSVLIAVS 9
           TDS+LIAVS
Sbjct: 598 TDSLLIAVS 606
>XP_006716142
          Length = 4927

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TDSVLIAVS 9
           TDS+LIAVS
Sbjct: 599 TDSLLIAVS 607
>XP_005250088
          Length = 4928

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TDSVLIAVS 9
           TDS+LIAVS
Sbjct: 599 TDSLLIAVS 607
>XP_006716141
          Length = 4959

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TDSVLIAVS 9
           TDS+LIAVS
Sbjct: 599 TDSLLIAVS 607
>XP_005250085
          Length = 4979

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TDSVLIAVS 9
           TDS+LIAVS
Sbjct: 599 TDSLLIAVS 607
>XP_006716140
          Length = 4982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TDSVLIAVS 9
           TDS+LIAVS
Sbjct: 599 TDSLLIAVS 607
>XP_005250084
          Length = 4982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TDSVLIAVS 9
           TDS+LIAVS
Sbjct: 599 TDSLLIAVS 607
>XP_005250083
          Length = 4982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TDSVLIAVS 9
           TDS+LIAVS
Sbjct: 598 TDSLLIAVS 606
>XP_005250082
          Length = 4983

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TDSVLIAVS 9
           TDS+LIAVS
Sbjct: 599 TDSLLIAVS 607
>NP_001005163
          Length = 318

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DSVLIAVS 9
           DS+LIA+S
Sbjct: 213 DSILIAIS 220
>NP_001092880
          Length = 1395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TDSVLIA 7
           TDSVL+A
Sbjct: 124 TDSVLVA 130
>NP_001092881
          Length = 1395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TDSVLIA 7
           TDSVL+A
Sbjct: 124 TDSVLVA 130
>NP_055525
          Length = 1395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TDSVLIA 7
           TDSVL+A
Sbjct: 124 TDSVLVA 130
>NP_001171656
          Length = 1395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TDSVLIA 7
           TDSVL+A
Sbjct: 124 TDSVLVA 130
>XP_005247977
          Length = 756

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TDSVLIAVS 9
           TDS L AVS
Sbjct: 242 TDSSLTAVS 250
>NP_055594
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TDSVLIAVS 9
           TDS L AVS
Sbjct: 242 TDSSLTAVS 250
>NP_001005289
          Length = 320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TDSVLIAVS 9
           +D +LIAVS
Sbjct: 217 SDVILIAVS 225
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.123    0.280 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 317,550
Number of extensions: 333
Number of successful extensions: 17
Number of sequences better than 10000.0: 17
Number of HSP's gapped: 17
Number of HSP's successfully gapped: 17
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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