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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              19     869
NP_004064                                                              17    4312
NP_066015                                                              16    5631
XP_005258381                                                           16    5631
XP_006722580                                                           16    5631
XP_006722579                                                           16    5631
XP_005258380                                                           16    5631
NP_000333                                                              16    7355
XP_005257650                                                           16    7355
XP_005257649                                                           16    7355
NP_001127835                                                           15    9605
NP_001157745                                                           15    9605
NP_001153777                                                           15    9605
NP_001074010                                                           15    9605
NP_079136                                                              15    9605
XP_006721334                                                           15    9605
XP_005254311                                                           15    9605
XP_006720508                                                           15    9605
XP_006720507                                                           15    9605
XP_005254310                                                           15    9605
XP_005254309                                                           15    9605
XP_005254306                                                           15    9605
XP_005254305                                                           15    9605
XP_005254304                                                           15    9605
XP_005254303                                                           15    9605
XP_006720506                                                           15    9605
XP_005254302                                                           15    9605
XP_005254301                                                           15    9605
XP_006720505                                                           15    9605
XP_005254300                                                           15    9605

>NP_004251
          Length = 1208

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TDQALLSLL 9
           TDQALL+LL
Sbjct: 684 TDQALLTLL 692



>NP_004064
          Length = 646

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TDQALLSL 8
           TDQALL L
Sbjct: 569 TDQALLML 576



>NP_066015
          Length = 2579

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD  LLSLL
Sbjct: 2137 TDSPLLSLL 2145



>XP_005258381
          Length = 2224

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD  LLSLL
Sbjct: 1782 TDSPLLSLL 1790



>XP_006722580
          Length = 2532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD  LLSLL
Sbjct: 2090 TDSPLLSLL 2098



>XP_006722579
          Length = 2544

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD  LLSLL
Sbjct: 2137 TDSPLLSLL 2145



>XP_005258380
          Length = 2578

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD  LLSLL
Sbjct: 2136 TDSPLLSLL 2144



>NP_000333
          Length = 911

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TDQALLSLL 9
           ++QALLSL+
Sbjct: 328 SEQALLSLV 336



>XP_005257650
          Length = 846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TDQALLSLL 9
           ++QALLSL+
Sbjct: 263 SEQALLSLV 271



>XP_005257649
          Length = 911

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TDQALLSLL 9
           ++QALLSL+
Sbjct: 328 SEQALLSLV 336



>NP_001127835
          Length = 1227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DQALLSL 8
           DQALLS+
Sbjct: 385 DQALLSV 391



>NP_001157745
          Length = 3065

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 2819 TDETLTSLL 2827



>NP_001153777
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TDQALLS 7
           TDQ LLS
Sbjct: 433 TDQGLLS 439



>NP_001074010
          Length = 2856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 2610 TDETLTSLL 2618



>NP_079136
          Length = 449

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TDQALLS 7
           TDQ LLS
Sbjct: 409 TDQGLLS 415



>XP_006721334
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TDQALLS 7
           TDQ LLS
Sbjct: 436 TDQGLLS 442



>XP_005254311
          Length = 1627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 1381 TDETLTSLL 1389



>XP_006720508
          Length = 2658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 2412 TDETLTSLL 2420



>XP_006720507
          Length = 2763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 2517 TDETLTSLL 2525



>XP_005254310
          Length = 2906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 2660 TDETLTSLL 2668



>XP_005254309
          Length = 2956

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 2710 TDETLTSLL 2718



>XP_005254306
          Length = 3066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 2820 TDETLTSLL 2828



>XP_005254305
          Length = 3114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 2868 TDETLTSLL 2876



>XP_005254304
          Length = 3115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 2869 TDETLTSLL 2877



>XP_005254303
          Length = 3115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 2869 TDETLTSLL 2877



>XP_006720506
          Length = 3115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 2869 TDETLTSLL 2877



>XP_005254302
          Length = 3115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 2869 TDETLTSLL 2877



>XP_005254301
          Length = 3115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 2869 TDETLTSLL 2877



>XP_006720505
          Length = 3115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 2869 TDETLTSLL 2877



>XP_005254300
          Length = 3115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TDQALLSLL 9
            TD+ L SLL
Sbjct: 2869 TDETLTSLL 2877



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.133    0.315 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 321,158
Number of extensions: 492
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)