Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              20     299
NP_001035957                                                           20     299
XP_006721990                                                           20     299
XP_006721989                                                           20     299
XP_005258041                                                           20     299
XP_006721988                                                           20     299
XP_006721987                                                           20     299
XP_006721986                                                           20     299
XP_005258040                                                           20     299
XP_006721985                                                           20     299
NP_112586                                                              18    1135
NP_004902                                                              17    4312
XP_006716248                                                           17    4312
NP_001269645                                                           16    5631
NP_036579                                                              16    5631
NP_001269646                                                           16    5631
NP_001269647                                                           16    5631
NP_061146                                                              16    5631
NP_954872                                                              16    5631
NP_872409                                                              16    5631
XP_006718595                                                           16    5631
XP_005250173                                                           16    5631
NP_892006                                                              16    7355
NP_149062                                                              16    7355
NP_065837                                                              16    7355
XP_005256125                                                           16    7355
XP_005256123                                                           16    7355
XP_005256124                                                           16    7355
XP_005256122                                                           16    7355
XP_005256121                                                           16    7355
XP_006715488                                                           16    7355
XP_006715487                                                           16    7355
XP_006715486                                                           16    7355
XP_006715485                                                           16    7355
XP_006715484                                                           16    7355
XP_006715483                                                           16    7355
XP_006715482                                                           16    7355
XP_006715481                                                           16    7355
XP_006715480                                                           16    7355
XP_006715479                                                           16    7355
XP_006715478                                                           16    7355
XP_006715477                                                           16    7355
XP_006715476                                                           16    7355
XP_006715475                                                           16    7355
XP_006715474                                                           16    7355
XP_006715473                                                           16    7355
XP_006715472                                                           16    7355
XP_006715471                                                           16    7355
XP_006715470                                                           16    7355
NP_066964                                                              15    9605
NP_001015887                                                           15    9605
NP_689751                                                              15    9605
XP_006713580                                                           15    9605
XP_006713579                                                           15    9605
XP_005246894                                                           15    9605
XP_005246893                                                           15    9605
NP_008955                                                              15    9605
>NP_000258
          Length = 2818

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TDLAQRFAF 9
            T+LAQRFAF
Sbjct: 2209 TELAQRFAF 2217
>NP_001035957
          Length = 2839

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TDLAQRFAF 9
            T+LAQRFAF
Sbjct: 2230 TELAQRFAF 2238
>XP_006721990
          Length = 2823

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TDLAQRFAF 9
            T+LAQRFAF
Sbjct: 2240 TELAQRFAF 2248
>XP_006721989
          Length = 2823

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TDLAQRFAF 9
            T+LAQRFAF
Sbjct: 2240 TELAQRFAF 2248
>XP_005258041
          Length = 2836

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TDLAQRFAF 9
            T+LAQRFAF
Sbjct: 2209 TELAQRFAF 2217
>XP_006721988
          Length = 2846

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TDLAQRFAF 9
            T+LAQRFAF
Sbjct: 2219 TELAQRFAF 2227
>XP_006721987
          Length = 2849

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TDLAQRFAF 9
            T+LAQRFAF
Sbjct: 2240 TELAQRFAF 2248
>XP_006721986
          Length = 2854

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TDLAQRFAF 9
            T+LAQRFAF
Sbjct: 2227 TELAQRFAF 2235
>XP_005258040
          Length = 2857

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TDLAQRFAF 9
            T+LAQRFAF
Sbjct: 2230 TELAQRFAF 2238
>XP_006721985
          Length = 2867

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TDLAQRFAF 9
            T+LAQRFAF
Sbjct: 2240 TELAQRFAF 2248
>NP_112586
          Length = 229

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   TDLAQRFA 8
           TDLAQ+FA
Sbjct: 160 TDLAQKFA 167
>NP_004902
          Length = 645

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TDLAQRF 7
           TDLA+RF
Sbjct: 241 TDLAKRF 247
>XP_006716248
          Length = 646

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TDLAQRF 7
           TDLA+RF
Sbjct: 241 TDLAKRF 247
>NP_001269645
          Length = 1225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DLAQRFA 8
           DLA+RFA
Sbjct: 959 DLARRFA 965
>NP_036579
          Length = 1225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DLAQRFA 8
           DLA+RFA
Sbjct: 959 DLARRFA 965
>NP_001269646
          Length = 1226

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DLAQRFA 8
           DLA+RFA
Sbjct: 959 DLARRFA 965
>NP_001269647
          Length = 1167

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DLAQRFA 8
           DLA+RFA
Sbjct: 901 DLARRFA 907
>NP_061146
          Length = 852

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           DLAQ+F +
Sbjct: 235 DLAQKFGY 242
>NP_954872
          Length = 799

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           DLAQ+F +
Sbjct: 235 DLAQKFGY 242
>NP_872409
          Length = 389

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAQRF 7
           DLAQRF
Sbjct: 206 DLAQRF 211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TDLAQRFA 8
           +D+A+RFA
Sbjct: 307 SDVAKRFA 314
>XP_006718595
          Length = 505

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAQRF 7
           DLAQRF
Sbjct: 206 DLAQRF 211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TDLAQRFA 8
           +D+A+RFA
Sbjct: 307 SDVAKRFA 314
>XP_005250173
          Length = 1222

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DLAQRFA 8
           DLA+RFA
Sbjct: 959 DLARRFA 965
>NP_892006
          Length = 8797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 484 DMAERFHF 491
>NP_149062
          Length = 8749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 491 DMAERFHF 498
>NP_065837
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TDLAQR 6
           TDLAQR
Sbjct: 439 TDLAQR 444
>XP_005256125
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TDLAQR 6
           TDLAQR
Sbjct: 439 TDLAQR 444
>XP_005256123
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TDLAQR 6
           TDLAQR
Sbjct: 439 TDLAQR 444
>XP_005256124
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TDLAQR 6
           TDLAQR
Sbjct: 439 TDLAQR 444
>XP_005256122
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TDLAQR 6
           TDLAQR
Sbjct: 439 TDLAQR 444
>XP_005256121
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TDLAQR 6
           TDLAQR
Sbjct: 439 TDLAQR 444
>XP_006715488
          Length = 8721

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 491 DMAERFHF 498
>XP_006715487
          Length = 8744

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 491 DMAERFHF 498
>XP_006715486
          Length = 8758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 491 DMAERFHF 498
>XP_006715485
          Length = 8793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 491 DMAERFHF 498
>XP_006715484
          Length = 8794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 491 DMAERFHF 498
>XP_006715483
          Length = 8795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 491 DMAERFHF 498
>XP_006715482
          Length = 8797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 484 DMAERFHF 491
>XP_006715481
          Length = 8799

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 444 DMAERFHF 451
>XP_006715480
          Length = 8799

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 491 DMAERFHF 498
>XP_006715479
          Length = 8804

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 491 DMAERFHF 498
>XP_006715478
          Length = 8809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 491 DMAERFHF 498
>XP_006715477
          Length = 8822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 467 DMAERFHF 474
>XP_006715476
          Length = 8823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 491 DMAERFHF 498
>XP_006715475
          Length = 8827

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 491 DMAERFHF 498
>XP_006715474
          Length = 8829

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 474 DMAERFHF 481
>XP_006715473
          Length = 8832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 491 DMAERFHF 498
>XP_006715472
          Length = 8839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 484 DMAERFHF 491
>XP_006715471
          Length = 8842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 491 DMAERFHF 498
>XP_006715470
          Length = 8846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DLAQRFAF 9
           D+A+RF F
Sbjct: 491 DMAERFHF 498
>NP_066964
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TDLAQRFA 8
           TDL+ RF+
Sbjct: 136 TDLSSRFS 143
>NP_001015887
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TDLAQRFAF 9
           +DL Q F+F
Sbjct: 339 SDLGQSFSF 347
>NP_689751
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TDLAQRFAF 9
           +DL Q F+F
Sbjct: 338 SDLGQSFSF 346
>XP_006713580
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TDLAQRFAF 9
           +DL Q F+F
Sbjct: 280 SDLGQSFSF 288
>XP_006713579
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TDLAQRFAF 9
           +DL Q F+F
Sbjct: 310 SDLGQSFSF 318
>XP_005246894
          Length = 449

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TDLAQRFA 8
           TDL+ RF+
Sbjct: 231 TDLSSRFS 238
>XP_005246893
          Length = 827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TDLAQRFA 8
           TDL+ RF+
Sbjct: 231 TDLSSRFS 238
>NP_008955
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   DLAQRFAF 9
           D+A  FAF
Sbjct: 217 DMADHFAF 224
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.343    0.142    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 347,095
Number of extensions: 629
Number of successful extensions: 59
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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