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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     509
XP_005262424                                                           20     509
NP_000192                                                              17    3301
NP_001011645                                                           17    4312
NP_000035                                                              17    4312
NP_891548                                                              16    7355
NP_001129627                                                           16    7355
NP_001129626                                                           16    7355
NP_001231118                                                           16    7355
NP_001231121                                                           16    7355
NP_055564                                                              16    7355
NP_001231119                                                           16    7355
NP_001231120                                                           16    7355
NP_001231122                                                           16    7355
NP_001278320                                                           16    7355
NP_001230361                                                           16    7355
NP_001230357                                                           16    7355
XP_005259931                                                           16    7355
XP_005259930                                                           16    7355
XP_006720406                                                           16    7355
XP_006720405                                                           16    7355
XP_006720404                                                           16    7355
XP_006720403                                                           16    7355
XP_006720402                                                           16    7355
XP_006720401                                                           16    7355
XP_006720400                                                           16    7355
XP_006720399                                                           16    7355
NP_078966                                                              15    9605
NP_006807                                                              15    9605
NP_055319                                                              15    9605
NP_001273990                                                           15    9605
NP_001273991                                                           15    9605

>NP_722576
          Length = 3080

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TDESTQRVT 9
           TDES QRVT
Sbjct: 871 TDESAQRVT 879



>XP_005262424
          Length = 2875

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TDESTQRVT 9
           TDES QRVT
Sbjct: 666 TDESAQRVT 674



>NP_000192
          Length = 532

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DESTQRVT 9
           DE TQR+T
Sbjct: 282 DEGTQRLT 289



>NP_001011645
          Length = 388

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TDESTQRVT 9
           T+E+TQ++T
Sbjct: 121 TEETTQKLT 129



>NP_000035
          Length = 920

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TDESTQRVT 9
           T+E+TQ++T
Sbjct: 653 TEETTQKLT 661



>NP_891548
          Length = 479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ESTQRVT 9
           E+TQR+T
Sbjct: 239 EATQRIT 245



>NP_001129627
          Length = 387

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ESTQRVT 9
           E+TQR+T
Sbjct: 147 EATQRIT 153



>NP_001129626
          Length = 486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ESTQRVT 9
           E+TQR+T
Sbjct: 246 EATQRIT 252



>NP_001231118
          Length = 1644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TDESTQRVT 9
           TD+  QRVT
Sbjct: 270 TDKHLQRVT 278



>NP_001231121
          Length = 1504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TDESTQRVT 9
           TD+  QRVT
Sbjct: 173 TDKHLQRVT 181



>NP_055564
          Length = 1472

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TDESTQRVT 9
           TD+  QRVT
Sbjct: 217 TDKHLQRVT 225



>NP_001231119
          Length = 1533

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TDESTQRVT 9
           TD+  QRVT
Sbjct: 202 TDKHLQRVT 210



>NP_001231120
          Length = 1463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TDESTQRVT 9
           TD+  QRVT
Sbjct: 132 TDKHLQRVT 140



>NP_001231122
          Length = 1347

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TDESTQRVT 9
          TD+  QRVT
Sbjct: 77 TDKHLQRVT 85



>NP_001278320
          Length = 325

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ESTQRVT 9
           E+TQR+T
Sbjct: 246 EATQRIT 252



>NP_001230361
          Length = 317

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ESTQRVT 9
           E+TQR+T
Sbjct: 246 EATQRIT 252



>NP_001230357
          Length = 486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ESTQRVT 9
           E+TQR+T
Sbjct: 246 EATQRIT 252



>XP_005259931
          Length = 716

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TDESTQRV 8
           TD ST+R+
Sbjct: 569 TDSSTRRI 576



>XP_005259930
          Length = 718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TDESTQRV 8
           TD ST+R+
Sbjct: 571 TDSSTRRI 578



>XP_006720406
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TDESTQRVT 9
           TD+  QRVT
Sbjct: 217 TDKHLQRVT 225



>XP_006720405
          Length = 1347

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TDESTQRVT 9
           TD+  QRVT
Sbjct: 217 TDKHLQRVT 225



>XP_006720404
          Length = 1477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TDESTQRVT 9
           TD+  QRVT
Sbjct: 217 TDKHLQRVT 225



>XP_006720403
          Length = 1486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TDESTQRVT 9
           TD+  QRVT
Sbjct: 217 TDKHLQRVT 225



>XP_006720402
          Length = 1487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TDESTQRVT 9
           TD+  QRVT
Sbjct: 217 TDKHLQRVT 225



>XP_006720401
          Length = 1504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TDESTQRVT 9
           TD+  QRVT
Sbjct: 217 TDKHLQRVT 225



>XP_006720400
          Length = 1526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TDESTQRVT 9
           TD+  QRVT
Sbjct: 217 TDKHLQRVT 225



>XP_006720399
          Length = 1548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TDESTQRVT 9
           TD+  QRVT
Sbjct: 217 TDKHLQRVT 225



>NP_078966
          Length = 14507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    STQRVT 9
            STQRVT
Sbjct: 1172 STQRVT 1177



>NP_006807
          Length = 356

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   DESTQRV 8
           DE+T+RV
Sbjct: 167 DETTERV 173



>NP_055319
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TDESTQRVT 9
          T+E T++VT
Sbjct: 91 TNEKTRKVT 99



>NP_001273990
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TDESTQRVT 9
           T+E T++VT
Sbjct: 105 TNEKTRKVT 113



>NP_001273991
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TDESTQRVT 9
          T+E T++VT
Sbjct: 91 TNEKTRKVT 99



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.292    0.104    0.247 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 485,519
Number of extensions: 903
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)