Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              18    1135
NP_001035957                                                           18    1135
XP_006721990                                                           18    1135
XP_006721989                                                           18    1135
XP_005258041                                                           18    1135
XP_006721988                                                           18    1135
XP_006721987                                                           18    1135
XP_006721986                                                           18    1135
XP_005258040                                                           18    1135
XP_006721985                                                           18    1135
NP_003827                                                              18    1935
NP_001177385                                                           16    7355
NP_001177386                                                           16    7355
NP_006082                                                              16    7355
XP_005254182                                                           16    7355
XP_005254181                                                           16    7355
NP_001106819                                                           15    9605
NP_001106820                                                           15    9605
NP_001388                                                              15    9605
NP_001106818                                                           15    9605
XP_006722532                                                           15    9605
XP_006722517                                                           15    9605
XP_006710461                                                           15    9605
>NP_000258
          Length = 2818

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TATEALLEI 9
            T TEALLEI
Sbjct: 2183 TVTEALLEI 2191
>NP_001035957
          Length = 2839

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TATEALLEI 9
            T TEALLEI
Sbjct: 2204 TVTEALLEI 2212
>XP_006721990
          Length = 2823

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TATEALLEI 9
            T TEALLEI
Sbjct: 2214 TVTEALLEI 2222
>XP_006721989
          Length = 2823

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TATEALLEI 9
            T TEALLEI
Sbjct: 2214 TVTEALLEI 2222
>XP_005258041
          Length = 2836

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TATEALLEI 9
            T TEALLEI
Sbjct: 2183 TVTEALLEI 2191
>XP_006721988
          Length = 2846

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TATEALLEI 9
            T TEALLEI
Sbjct: 2193 TVTEALLEI 2201
>XP_006721987
          Length = 2849

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TATEALLEI 9
            T TEALLEI
Sbjct: 2214 TVTEALLEI 2222
>XP_006721986
          Length = 2854

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TATEALLEI 9
            T TEALLEI
Sbjct: 2201 TVTEALLEI 2209
>XP_005258040
          Length = 2857

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TATEALLEI 9
            T TEALLEI
Sbjct: 2204 TVTEALLEI 2212
>XP_006721985
          Length = 2867

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TATEALLEI 9
            T TEALLEI
Sbjct: 2214 TVTEALLEI 2222
>NP_003827
          Length = 383

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  TATEALLEI 9
          TATEALL +
Sbjct: 2  TATEALLRV 10
>NP_001177385
          Length = 475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TEALLEI 9
           TEALLE+
Sbjct: 122 TEALLEL 128
>NP_001177386
          Length = 475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TEALLEI 9
           TEALLE+
Sbjct: 122 TEALLEL 128
>NP_006082
          Length = 480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TEALLEI 9
           TEALLE+
Sbjct: 127 TEALLEL 133
>XP_005254182
          Length = 475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TEALLEI 9
           TEALLE+
Sbjct: 122 TEALLEL 128
>XP_005254181
          Length = 476

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TEALLEI 9
           TEALLE+
Sbjct: 123 TEALLEL 129
>NP_001106819
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ATEALLEI 9
           ATE +LEI
Sbjct: 448 ATEIILEI 455
>NP_001106820
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ATEALLEI 9
           ATE +LEI
Sbjct: 461 ATEIILEI 468
>NP_001388
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ATEALLEI 9
           ATE +LEI
Sbjct: 464 ATEIILEI 471
>NP_001106818
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ATEALLEI 9
           ATE +LEI
Sbjct: 452 ATEIILEI 459
>XP_006722532
          Length = 585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ATEALLEI 9
           +TEALL++
Sbjct: 471 STEALLQV 478
>XP_006722517
          Length = 673

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ATEALLEI 9
           +TEALL++
Sbjct: 527 STEALLQV 534
>XP_006710461
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ATEALLEI 9
           ATE +LEI
Sbjct: 447 ATEIILEI 454
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.121    0.273 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 330,225
Number of extensions: 432
Number of successful extensions: 23
Number of sequences better than 10000.0: 23
Number of HSP's gapped: 23
Number of HSP's successfully gapped: 23
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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