Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138389                                                           18    1135
NP_001138386                                                           18    1135
NP_000132                                                              18    1135
NP_075259                                                              18    1135
NP_001138385                                                           18    1135
XP_006717776                                                           18    1135
XP_006717773                                                           18    1135
XP_006717772                                                           18    1135
XP_006717771                                                           18    1135
NP_001162593                                                           17    3301
NP_002016                                                              17    3301
NP_001162594                                                           17    3301
NP_001162595                                                           17    3301
NP_001162596                                                           17    3301
NP_001164099                                                           17    3301
NP_000381                                                              17    4312
XP_006724678                                                           17    4312
NP_001278340                                                           16    5631
NP_620305                                                              16    5631
NP_115571                                                              16    5631
XP_006724107                                                           16    5631
XP_006724106                                                           16    5631
NP_000074                                                              16    7355
NP_005261                                                              16    7355
NP_055559                                                              16    7355
NP_001127853                                                           16    7355
NP_001138508                                                           16    7355
NP_031383                                                              16    7355
XP_005258187                                                           16    7355
XP_005265671                                                           16    7355
XP_005265670                                                           16    7355
XP_005265669                                                           16    7355
XP_006713493                                                           16    7355
XP_006713492                                                           16    7355
XP_005265668                                                           16    7355
XP_006712486                                                           16    7355
XP_006712485                                                           16    7355
NP_001073678                                                           16    7355
NP_060855                                                              15    9605
NP_056996                                                              15    9605
NP_001107018                                                           15    9605
NP_001269461                                                           15    9605
NP_056154                                                              15    9605
NP_001269460                                                           15    9605
NP_001107019                                                           15    9605
NP_057441                                                              15    9605
NP_055445                                                              15    9605
NP_852107                                                              15    9605
XP_006723822                                                           15    9605
XP_006723022                                                           15    9605
XP_005255053                                                           15    9605
XP_005267468                                                           15    9605
XP_005267467                                                           15    9605
XP_005250985                                                           15    9605
XP_006716634                                                           15    9605
NP_055765                                                              15    9605
NP_001116801                                                           15    9605
>NP_001138389
          Length = 705

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TASSTVDSE 9
           TAS TVDSE
Sbjct: 108 TASRTVDSE 116
>NP_001138386
          Length = 709

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TASSTVDSE 9
           TAS TVDSE
Sbjct: 108 TASRTVDSE 116
>NP_000132
          Length = 821

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TASSTVDSE 9
           TAS TVDSE
Sbjct: 108 TASRTVDSE 116
>NP_075259
          Length = 822

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TASSTVDSE 9
           TAS TVDSE
Sbjct: 108 TASRTVDSE 116
>NP_001138385
          Length = 769

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TASSTVDSE 9
           TAS TVDSE
Sbjct: 108 TASRTVDSE 116
>XP_006717776
          Length = 806

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TASSTVDSE 9
           TAS TVDSE
Sbjct: 127 TASRTVDSE 135
>XP_006717773
          Length = 807

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TASSTVDSE 9
           TAS TVDSE
Sbjct: 127 TASRTVDSE 135
>XP_006717772
          Length = 838

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TASSTVDSE 9
           TAS TVDSE
Sbjct: 127 TASRTVDSE 135
>XP_006717771
          Length = 839

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TASSTVDSE 9
           TAS TVDSE
Sbjct: 127 TASRTVDSE 135
>NP_001162593
          Length = 1276

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TASSTVDSE 9
           T SST DSE
Sbjct: 467 TESSTTDSE 475
>NP_002016
          Length = 1311

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TASSTVDSE 9
           T SST DSE
Sbjct: 500 TESSTTDSE 508
>NP_001162594
          Length = 1301

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TASSTVDSE 9
           T SST DSE
Sbjct: 490 TESSTTDSE 498
>NP_001162595
          Length = 1276

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TASSTVDSE 9
           T SST DSE
Sbjct: 465 TESSTTDSE 473
>NP_001162596
          Length = 1272

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TASSTVDSE 9
           T SST DSE
Sbjct: 461 TESSTTDSE 469
>NP_001164099
          Length = 952

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TASSTVDSE 9
           T SST DSE
Sbjct: 141 TESSTTDSE 149
>NP_000381
          Length = 653

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TASSTVD 7
           TASST+D
Sbjct: 347 TASSTID 353
>XP_006724678
          Length = 632

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TASSTVD 7
           TASST+D
Sbjct: 326 TASSTID 332
>NP_001278340
          Length = 2108

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ASSTVDSE 9
           ASST+DS+
Sbjct: 757 ASSTMDSQ 764
>NP_620305
          Length = 2426

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ASSTVDSE 9
           ASST+DS+
Sbjct: 757 ASSTMDSQ 764
>NP_115571
          Length = 2303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ASSTVDSE 9
           ASST+DS+
Sbjct: 757 ASSTMDSQ 764
>XP_006724107
          Length = 2298

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ASSTVDSE 9
           ASST+DS+
Sbjct: 757 ASSTMDSQ 764
>XP_006724106
          Length = 2459

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ASSTVDSE 9
           ASST+DS+
Sbjct: 757 ASSTMDSQ 764
>NP_000074
          Length = 988

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ASSTVDSE 9
          +SSTVDS+
Sbjct: 84 SSSTVDSK 91
>NP_005261
          Length = 1586

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SSTVDSE 9
            SSTVDS+
Sbjct: 1497 SSTVDSQ 1503
>NP_055559
          Length = 795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SSTVDSE 9
          SST+DSE
Sbjct: 43 SSTLDSE 49
>NP_001127853
          Length = 817

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SSTVDSE 9
          SST+DSE
Sbjct: 43 SSTLDSE 49
>NP_001138508
          Length = 737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TASSTVDS 8
           TASS VDS
Sbjct: 602 TASSYVDS 609
>NP_031383
          Length = 738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TASSTVDS 8
           TASS VDS
Sbjct: 603 TASSYVDS 610
>XP_005258187
          Length = 621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TASSTVDS 8
           TASS VDS
Sbjct: 367 TASSFVDS 374
>XP_005265671
          Length = 795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SSTVDSE 9
          SST+DSE
Sbjct: 43 SSTLDSE 49
>XP_005265670
          Length = 817

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SSTVDSE 9
          SST+DSE
Sbjct: 43 SSTLDSE 49
>XP_005265669
          Length = 817

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SSTVDSE 9
          SST+DSE
Sbjct: 43 SSTLDSE 49
>XP_006713493
          Length = 817

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SSTVDSE 9
          SST+DSE
Sbjct: 43 SSTLDSE 49
>XP_006713492
          Length = 817

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SSTVDSE 9
          SST+DSE
Sbjct: 43 SSTLDSE 49
>XP_005265668
          Length = 817

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SSTVDSE 9
          SST+DSE
Sbjct: 43 SSTLDSE 49
>XP_006712486
          Length = 1504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SSTVDSE 9
            SSTVDS+
Sbjct: 1415 SSTVDSQ 1421
>XP_006712485
          Length = 1569

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SSTVDSE 9
            SSTVDS+
Sbjct: 1480 SSTVDSQ 1486
>NP_001073678
          Length = 621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TASSTVDS 8
           TASS VDS
Sbjct: 367 TASSFVDS 374
>NP_060855
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SSTVDSE 9
           SST DSE
Sbjct: 339 SSTADSE 345
>NP_056996
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TASSTVDSE 9
            T SST+D E
Sbjct: 1079 THSSTLDEE 1087
>NP_001107018
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ASSTVDSE 9
           +SST DSE
Sbjct: 242 SSSTFDSE 249
>NP_001269461
          Length = 1102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SSTVDSE 9
            +ST+DSE
Sbjct: 1066 NSTIDSE 1072
>NP_056154
          Length = 1102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SSTVDSE 9
            +ST+DSE
Sbjct: 1066 NSTIDSE 1072
>NP_001269460
          Length = 1102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SSTVDSE 9
            +ST+DSE
Sbjct: 1066 NSTIDSE 1072
>NP_001107019
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ASSTVDSE 9
          +SST DSE
Sbjct: 82 SSSTFDSE 89
>NP_057441
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ASSTVDSE 9
           +SST DSE
Sbjct: 242 SSSTFDSE 249
>NP_055445
          Length = 1267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TASSTVD 7
           TASST D
Sbjct: 838 TASSTAD 844
>NP_852107
          Length = 1102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SSTVDSE 9
            +ST+DSE
Sbjct: 1066 NSTIDSE 1072
>XP_006723822
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SSTVDSE 9
            +ST+DSE
Sbjct: 1075 NSTIDSE 1081
>XP_006723022
          Length = 130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  SSTVDSE 9
          SSTVD E
Sbjct: 36 SSTVDGE 42
>XP_005255053
          Length = 1267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TASSTVD 7
           TASST D
Sbjct: 838 TASSTAD 844
>XP_005267468
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSTVDSE 9
           SSTV+SE
Sbjct: 304 SSTVESE 310
>XP_005267467
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSTVDSE 9
           SSTV+SE
Sbjct: 304 SSTVESE 310
>XP_005250985
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TASSTVDSE 9
            T SST+D E
Sbjct: 1079 THSSTLDEE 1087
>XP_006716634
          Length = 1420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TASSTVDSE 9
            T SST+D E
Sbjct: 1093 THSSTLDEE 1101
>NP_055765
          Length = 644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSTVDSE 9
           SSTV+SE
Sbjct: 304 SSTVESE 310
>NP_001116801
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSTVDSE 9
           SSTV+SE
Sbjct: 304 SSTVESE 310
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.270   0.0868    0.184 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 368,922
Number of extensions: 401
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.4 bits)
S2: 28 (15.4 bits)

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