Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005179                                                              17    2528
XP_006722562                                                           17    3301
XP_006722561                                                           17    3301
XP_006722560                                                           17    3301
XP_006722559                                                           17    3301
XP_005266781                                                           17    3301
XP_006722558                                                           17    3301
XP_005266780                                                           17    3301
XP_005266779                                                           17    3301
NP_001127694                                                           17    3301
NP_150366                                                              17    3301
NP_060651                                                              17    3301
NP_055638                                                              15    9605
NP_998820                                                              15    9605
NP_001171914                                                           15    9605
NP_061852                                                              15    9605
NP_001006635                                                           15    9605
NP_060524                                                              15    9605
NP_001269323                                                           15    9605
XP_006721122                                                           15    9605
XP_006721120                                                           15    9605
XP_006719067                                                           15    9605
XP_006719066                                                           15    9605
XP_005253800                                                           15    9605
XP_005253798                                                           15    9605
XP_005253797                                                           15    9605
XP_005253796                                                           15    9605
XP_006719065                                                           15    9605
XP_006719064                                                           15    9605
XP_006719063                                                           15    9605
XP_006719062                                                           15    9605
XP_005253795                                                           15    9605
XP_005253794                                                           15    9605
XP_005253793                                                           15    9605
XP_005253792                                                           15    9605
XP_006719061                                                           15    9605
XP_005253791                                                           15    9605
XP_006717302                                                           15    9605
XP_005252200                                                           15    9605
XP_006717301                                                           15    9605
XP_005252199                                                           15    9605
XP_006717300                                                           15    9605
XP_005252196                                                           15    9605
XP_005252195                                                           15    9605
XP_005252194                                                           15    9605
>NP_005179
          Length = 906

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TASKAASDS 9
           TASKAAS S
Sbjct: 518 TASKAASGS 526
>XP_006722562
          Length = 1060

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TASKAASDS 9
           +A KAASDS
Sbjct: 278 SAKKAASDS 286
>XP_006722561
          Length = 1094

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TASKAASDS 9
           +A KAASDS
Sbjct: 278 SAKKAASDS 286
>XP_006722560
          Length = 1295

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TASKAASDS 9
           +A KAASDS
Sbjct: 278 SAKKAASDS 286
>XP_006722559
          Length = 1297

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TASKAASDS 9
           +A KAASDS
Sbjct: 278 SAKKAASDS 286
>XP_005266781
          Length = 1301

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TASKAASDS 9
           +A KAASDS
Sbjct: 278 SAKKAASDS 286
>XP_006722558
          Length = 1301

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TASKAASDS 9
           +A KAASDS
Sbjct: 278 SAKKAASDS 286
>XP_005266780
          Length = 1301

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TASKAASDS 9
           +A KAASDS
Sbjct: 278 SAKKAASDS 286
>XP_005266779
          Length = 1301

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TASKAASDS 9
           +A KAASDS
Sbjct: 278 SAKKAASDS 286
>NP_001127694
          Length = 471

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TASKAASDS 9
           TA KAASD+
Sbjct: 423 TAPKAASDA 431
>NP_150366
          Length = 471

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TASKAASDS 9
           TA KAASD+
Sbjct: 423 TAPKAASDA 431
>NP_060651
          Length = 1301

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TASKAASDS 9
           +A KAASDS
Sbjct: 278 SAKKAASDS 286
>NP_055638
          Length = 2134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1681 TASEAKSDT 1689
>NP_998820
          Length = 2634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 2181 TASEAKSDT 2189
>NP_001171914
          Length = 2642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 2189 TASEAKSDT 2197
>NP_061852
          Length = 2382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1929 TASEAKSDT 1937
>NP_001006635
          Length = 881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TASKAASDS 9
           TASK  +DS
Sbjct: 832 TASKIVTDS 840
>NP_060524
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TASKAASDS 9
           TASK  +DS
Sbjct: 754 TASKIVTDS 762
>NP_001269323
          Length = 2297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    TASKAASD 8
            TAS AASD
Sbjct: 2286 TASFAASD 2293
>XP_006721122
          Length = 804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TASKAASDS 9
           TASK  +DS
Sbjct: 755 TASKIVTDS 763
>XP_006721120
          Length = 880

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TASKAASDS 9
           TASK  +DS
Sbjct: 831 TASKIVTDS 839
>XP_006719067
          Length = 2228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1775 TASEAKSDT 1783
>XP_006719066
          Length = 2381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1928 TASEAKSDT 1936
>XP_005253800
          Length = 2013

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1522 TASEAKSDT 1530
>XP_005253798
          Length = 2145

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1654 TASEAKSDT 1662
>XP_005253797
          Length = 2146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1655 TASEAKSDT 1663
>XP_005253796
          Length = 2173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1682 TASEAKSDT 1690
>XP_006719065
          Length = 2174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1683 TASEAKSDT 1691
>XP_006719064
          Length = 2229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1776 TASEAKSDT 1784
>XP_006719063
          Length = 2266

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1775 TASEAKSDT 1783
>XP_006719062
          Length = 2267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1776 TASEAKSDT 1784
>XP_005253795
          Length = 2280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1929 TASEAKSDT 1937
>XP_005253794
          Length = 2391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1900 TASEAKSDT 1908
>XP_005253793
          Length = 2392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1901 TASEAKSDT 1909
>XP_005253792
          Length = 2419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1928 TASEAKSDT 1936
>XP_006719061
          Length = 2419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1928 TASEAKSDT 1936
>XP_005253791
          Length = 2420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TASKAASDS 9
            TAS+A SD+
Sbjct: 1929 TASEAKSDT 1937
>XP_006717302
          Length = 2148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    TASKAASD 8
            TAS AASD
Sbjct: 2137 TASFAASD 2144
>XP_005252200
          Length = 2208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    TASKAASD 8
            TAS AASD
Sbjct: 2197 TASFAASD 2204
>XP_006717301
          Length = 2212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    TASKAASD 8
            TAS AASD
Sbjct: 2201 TASFAASD 2208
>XP_005252199
          Length = 2215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    TASKAASD 8
            TAS AASD
Sbjct: 2204 TASFAASD 2211
>XP_006717300
          Length = 2227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    TASKAASD 8
            TAS AASD
Sbjct: 2216 TASFAASD 2223
>XP_005252196
          Length = 2242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    TASKAASD 8
            TAS AASD
Sbjct: 2231 TASFAASD 2238
>XP_005252195
          Length = 2259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    TASKAASD 8
            TAS AASD
Sbjct: 2248 TASFAASD 2255
>XP_005252194
          Length = 2260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    TASKAASD 8
            TAS AASD
Sbjct: 2249 TASFAASD 2256
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.270   0.0808    0.169 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 213,671
Number of extensions: 189
Number of successful extensions: 45
Number of sequences better than 10000.0: 45
Number of HSP's gapped: 45
Number of HSP's successfully gapped: 45
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.5 bits)
S2: 28 (15.4 bits)

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