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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002430                                                              20     390
NP_001027454                                                           17    3301
XP_005269189                                                           17    3301
XP_005269187                                                           17    3301
NP_001025226                                                           17    4312
NP_001164                                                              17    4312
XP_005267693                                                           17    4312
XP_005267692                                                           17    4312
NP_036336                                                              16    5631
NP_005712                                                              16    7355
NP_852468                                                              16    7355
NP_598395                                                              16    7355
NP_001027455                                                           15    9605
NP_071504                                                              15    9605
NP_000911                                                              15    9605
NP_001035806                                                           15    9605
NP_683692                                                              15    9605
NP_001192246                                                           15    9605
XP_006718641                                                           15    9605
XP_005274089                                                           15    9605
XP_005274088                                                           15    9605
XP_006718640                                                           15    9605
XP_005248208                                                           15    9605
XP_005248207                                                           15    9605
XP_006714021                                                           15    9605
NP_892015                                                              15    9605

>NP_002430
          Length = 1137

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   AKVGDKTE 9
           AKVGDKTE
Sbjct: 694 AKVGDKTE 701



>NP_001027454
          Length = 454

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AKVGDKTE 9
           A+VG+KTE
Sbjct: 329 AEVGEKTE 336



>XP_005269189
          Length = 382

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AKVGDKTE 9
           A+VG+KTE
Sbjct: 257 AEVGEKTE 264



>XP_005269187
          Length = 414

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AKVGDKTE 9
           A+VG+KTE
Sbjct: 289 AEVGEKTE 296



>NP_001025226
          Length = 1502

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    AKVGDKTE 9
            AK+ DKTE
Sbjct: 1358 AKIPDKTE 1365



>NP_001164
          Length = 1501

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    AKVGDKTE 9
            AK+ DKTE
Sbjct: 1357 AKIPDKTE 1364



>XP_005267693
          Length = 1502

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    AKVGDKTE 9
            AK+ DKTE
Sbjct: 1358 AKIPDKTE 1365



>XP_005267692
          Length = 1502

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    AKVGDKTE 9
            AK+ DKTE
Sbjct: 1358 AKIPDKTE 1365



>NP_036336
          Length = 822

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KVGDKTE 9
           KVG KTE
Sbjct: 119 KVGSKTE 125



>NP_005712
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TAKVGDKTE 9
          +AKVGD+ +
Sbjct: 40 SAKVGDQAQ 48



>NP_852468
          Length = 140

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TAKVGDKTE 9
          TAK+ D+T+
Sbjct: 39 TAKIEDETQ 47



>NP_598395
          Length = 200

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TAKVGDKTE 9
          TAK+ D+T+
Sbjct: 39 TAKIEDETQ 47



>NP_001027455
          Length = 345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KVGDKTE 9
           +VG+KTE
Sbjct: 221 QVGEKTE 227



>NP_071504
          Length = 1178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KVGDKTE 9
           K+GDK E
Sbjct: 148 KMGDKVE 154



>NP_000911
          Length = 1178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KVGDKTE 9
           K+GDK E
Sbjct: 148 KMGDKVE 154



>NP_001035806
          Length = 1178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KVGDKTE 9
           K+GDK E
Sbjct: 148 KMGDKVE 154



>NP_683692
          Length = 3051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KVGDKTE 9
           K GD+TE
Sbjct: 752 KTGDETE 758



>NP_001192246
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TAKVGDKT 8
           TAK G KT
Sbjct: 142 TAKPGSKT 149



>XP_006718641
          Length = 1178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KVGDKTE 9
           K+GDK E
Sbjct: 148 KMGDKVE 154



>XP_005274089
          Length = 1178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KVGDKTE 9
           K+GDK E
Sbjct: 148 KMGDKVE 154



>XP_005274088
          Length = 1178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KVGDKTE 9
           K+GDK E
Sbjct: 148 KMGDKVE 154



>XP_006718640
          Length = 1178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KVGDKTE 9
           K+GDK E
Sbjct: 148 KMGDKVE 154



>XP_005248208
          Length = 3097

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KVGDKTE 9
           K GD+TE
Sbjct: 752 KTGDETE 758



>XP_005248207
          Length = 3098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KVGDKTE 9
           K GD+TE
Sbjct: 752 KTGDETE 758



>XP_006714021
          Length = 3112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KVGDKTE 9
           K GD+TE
Sbjct: 752 KTGDETE 758



>NP_892015
          Length = 269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TAKVGDKT 8
           TAK G KT
Sbjct: 141 TAKPGSKT 148



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.292    0.114    0.287 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 503,342
Number of extensions: 719
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)