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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003290                                                              18    1135
NP_001191111                                                           16    7355
NP_001191112                                                           16    7355
NP_002488                                                              16    7355
XP_005273204                                                           16    7355
NP_001007594                                                           15    9605
NP_001254657                                                           15    9605
NP_004919                                                              15    9605
NP_001258369                                                           15    9605
NP_001258371                                                           15    9605
NP_001258370                                                           15    9605
NP_443204                                                              15    9605
XP_006724116                                                           15    9605
XP_006724115                                                           15    9605
XP_006724114                                                           15    9605

>NP_003290
          Length = 803

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TAITLVLKE 9
           T ITLVLKE
Sbjct: 245 TTITLVLKE 253



>NP_001191111
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TAITLVLKE 9
           T +TL LKE
Sbjct: 118 TQLTLALKE 126



>NP_001191112
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TAITLVLKE 9
           T +TL LKE
Sbjct: 118 TQLTLALKE 126



>NP_002488
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TAITLVLKE 9
           T +TL LKE
Sbjct: 118 TQLTLALKE 126



>XP_005273204
          Length = 437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TAITLVLKE 9
           T +TL LKE
Sbjct: 118 TQLTLALKE 126



>NP_001007594
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TAITLVLKE 9
           TAI L LKE
Sbjct: 99  TAINLGLKE 107



>NP_001254657
          Length = 262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TAITLVLKE 9
          +AIT +LKE
Sbjct: 25 SAITEILKE 33



>NP_004919
          Length = 256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TAITLVLKE 9
           TAI L+L+E
Sbjct: 218 TAILLLLRE 226



>NP_001258369
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TAITLVLKE 9
           TAI L+L+E
Sbjct: 217 TAILLLLRE 225



>NP_001258371
          Length = 214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TAITLVLKE 9
           TAI L+L+E
Sbjct: 176 TAILLLLRE 184



>NP_001258370
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TAITLVLKE 9
           TAI L+L+E
Sbjct: 337 TAILLLLRE 345



>NP_443204
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TAITLVLKE 9
           T  TLVLKE
Sbjct: 141 TLDTLVLKE 149



>XP_006724116
          Length = 148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TAITLVLKE 9
           TAI L+L+E
Sbjct: 110 TAILLLLRE 118



>XP_006724115
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TAITLVLKE 9
           TAI L+L+E
Sbjct: 242 TAILLLLRE 250



>XP_006724114
          Length = 281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TAITLVLKE 9
           TAI L+L+E
Sbjct: 243 TAILLLLRE 251



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.130    0.301 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 348,882
Number of extensions: 380
Number of successful extensions: 15
Number of sequences better than 10000.0: 15
Number of HSP's gapped: 15
Number of HSP's successfully gapped: 15
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)