Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_057652                                                              16    7355
NP_001245233                                                           16    7355
XP_006712899                                                           16    7355
XP_005263899                                                           16    7355
XP_006712898                                                           16    7355
XP_005263897                                                           16    7355
XP_006712896                                                           16    7355
XP_006712893                                                           16    7355
XP_006712892                                                           16    7355
XP_005263892                                                           16    7355
XP_006712891                                                           16    7355
NP_001186681                                                           15    9605
NP_001129524                                                           15    9605
NP_689572                                                              15    9605
NP_001186682                                                           15    9605
XP_006723073                                                           15    9605
XP_006723072                                                           15    9605
XP_005258564                                                           15    9605
XP_005258563                                                           15    9605
XP_005258562                                                           15    9605
>NP_057652
          Length = 469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TAIFSTT 7
           +AIFSTT
Sbjct: 232 SAIFSTT 238
>NP_001245233
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAIFSTTRL 9
           TAI S+TRL
Sbjct: 110 TAINSSTRL 118
>XP_006712899
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAIFSTTRL 9
           TAI S+TRL
Sbjct: 110 TAINSSTRL 118
>XP_005263899
          Length = 356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAIFSTTRL 9
           TAI S+TRL
Sbjct: 110 TAINSSTRL 118
>XP_006712898
          Length = 360

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAIFSTTRL 9
           TAI S+TRL
Sbjct: 110 TAINSSTRL 118
>XP_005263897
          Length = 422

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAIFSTTRL 9
           TAI S+TRL
Sbjct: 110 TAINSSTRL 118
>XP_006712896
          Length = 426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAIFSTTRL 9
           TAI S+TRL
Sbjct: 110 TAINSSTRL 118
>XP_006712893
          Length = 314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAIFSTTRL 9
           TAI S+TRL
Sbjct: 110 TAINSSTRL 118
>XP_006712892
          Length = 338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAIFSTTRL 9
           TAI S+TRL
Sbjct: 110 TAINSSTRL 118
>XP_005263892
          Length = 354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAIFSTTRL 9
           TAI S+TRL
Sbjct: 110 TAINSSTRL 118
>XP_006712891
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAIFSTTRL 9
           TAI S+TRL
Sbjct: 110 TAINSSTRL 118
>NP_001186681
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IFSTTRL 9
           IF+TTR+
Sbjct: 310 IFNTTRI 316
>NP_001129524
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IFSTTRL 9
           IF+TTR+
Sbjct: 299 IFNTTRI 305
>NP_689572
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IFSTTRL 9
           IF+TTR+
Sbjct: 310 IFNTTRI 316
>NP_001186682
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IFSTTRL 9
           IF+TTR+
Sbjct: 310 IFNTTRI 316
>XP_006723073
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IFSTTRL 9
           IF+TTR+
Sbjct: 310 IFNTTRI 316
>XP_006723072
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IFSTTRL 9
           IF+TTR+
Sbjct: 181 IFNTTRI 187
>XP_005258564
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IFSTTRL 9
           IF+TTR+
Sbjct: 310 IFNTTRI 316
>XP_005258563
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IFSTTRL 9
           IF+TTR+
Sbjct: 310 IFNTTRI 316
>XP_005258562
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IFSTTRL 9
           IF+TTR+
Sbjct: 310 IFNTTRI 316
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.129    0.329 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 302,131
Number of extensions: 309
Number of successful extensions: 20
Number of sequences better than 10000.0: 20
Number of HSP's gapped: 20
Number of HSP's successfully gapped: 20
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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