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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              20     390
XP_006718908                                                           20     390
XP_005271621                                                           20     390
XP_006718907                                                           20     390
XP_006718906                                                           20     390
XP_005271619                                                           20     390
XP_005271618                                                           20     390
NP_057526                                                              16    5631
NP_001185470                                                           16    5631
NP_001035548                                                           16    5631
NP_443116                                                              16    5631
NP_001128635                                                           16    5631
XP_005258534                                                           16    5631
XP_005258533                                                           16    5631
XP_005272073                                                           16    5631
XP_005272072                                                           16    5631
NP_073600                                                              16    7355
NP_001128567                                                           16    7355
NP_001787                                                              15    9605
NP_006718                                                              15    9605
XP_005260860                                                           15    9605
XP_005260859                                                           15    9605
XP_005260858                                                           15    9605
XP_005260857                                                           15    9605
XP_006723671                                                           15    9605
XP_006723670                                                           15    9605
XP_005260854                                                           15    9605
XP_006723669                                                           15    9605
XP_005266741                                                           15    9605
XP_005266739                                                           15    9605
XP_005255817                                                           15    9605
XP_005255816                                                           15    9605
NP_071927                                                              15    9605
NP_114097                                                              15    9605

>NP_000042
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    YTVKVQRE 9
            YTVKVQRE
Sbjct: 2437 YTVKVQRE 2444



>XP_006718908
          Length = 1708

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    YTVKVQRE 9
            YTVKVQRE
Sbjct: 1089 YTVKVQRE 1096



>XP_005271621
          Length = 2708

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    YTVKVQRE 9
            YTVKVQRE
Sbjct: 2089 YTVKVQRE 2096



>XP_006718907
          Length = 3050

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    YTVKVQRE 9
            YTVKVQRE
Sbjct: 2431 YTVKVQRE 2438



>XP_006718906
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    YTVKVQRE 9
            YTVKVQRE
Sbjct: 2437 YTVKVQRE 2444



>XP_005271619
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    YTVKVQRE 9
            YTVKVQRE
Sbjct: 2437 YTVKVQRE 2444



>XP_005271618
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    YTVKVQRE 9
            YTVKVQRE
Sbjct: 2437 YTVKVQRE 2444



>NP_057526
          Length = 948

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SYTVKVQRE 9
           S+++K++RE
Sbjct: 202 SFSIKIRRE 210



>NP_001185470
          Length = 941

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SYTVKVQRE 9
           S+++K++RE
Sbjct: 202 SFSIKIRRE 210



>NP_001035548
          Length = 941

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SYTVKVQRE 9
           S+++K++RE
Sbjct: 202 SFSIKIRRE 210



>NP_443116
          Length = 698

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SYTVKVQRE 9
          SY+++VQR+
Sbjct: 33 SYSLQVQRQ 41



>NP_001128635
          Length = 602

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SYTVKVQRE 9
          SY+++VQR+
Sbjct: 33 SYSLQVQRQ 41



>XP_005258534
          Length = 479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SYTVKVQRE 9
          SY+++VQR+
Sbjct: 57 SYSLQVQRQ 65



>XP_005258533
          Length = 706

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SYTVKVQRE 9
          SY+++VQR+
Sbjct: 57 SYSLQVQRQ 65



>XP_005272073
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SYTVKVQRE 9
           S+++K++RE
Sbjct: 202 SFSIKIRRE 210



>XP_005272072
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SYTVKVQRE 9
           S+++K++RE
Sbjct: 202 SFSIKIRRE 210



>NP_073600
          Length = 1204

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SYTVKVQR 8
            S+T KVQR
Sbjct: 1012 SHTYKVQR 1019



>NP_001128567
          Length = 1204

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SYTVKVQR 8
            S+T KVQR
Sbjct: 1012 SHTYKVQR 1019



>NP_001787
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYTVKVQ 7
           SYT+KV+
Sbjct: 350 SYTLKVE 356



>NP_006718
          Length = 788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   YTVKVQRE 9
           YT+KV+ E
Sbjct: 344 YTLKVEAE 351



>XP_005260860
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YTVKVQRE 9
           YT KVQ E
Sbjct: 95  YTAKVQVE 102



>XP_005260859
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YTVKVQRE 9
           YT KVQ E
Sbjct: 95  YTAKVQVE 102



>XP_005260858
          Length = 643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YTVKVQRE 9
           YT KVQ E
Sbjct: 95  YTAKVQVE 102



>XP_005260857
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YTVKVQRE 9
           YT KVQ E
Sbjct: 95  YTAKVQVE 102



>XP_006723671
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YTVKVQRE 9
           YT KVQ E
Sbjct: 95  YTAKVQVE 102



>XP_006723670
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YTVKVQRE 9
           YT KVQ E
Sbjct: 95  YTAKVQVE 102



>XP_005260854
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YTVKVQRE 9
           YT KVQ E
Sbjct: 95  YTAKVQVE 102



>XP_006723669
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YTVKVQRE 9
           YT KVQ E
Sbjct: 95  YTAKVQVE 102



>XP_005266741
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYTVKVQ 7
           SYT+KV+
Sbjct: 348 SYTLKVE 354



>XP_005266739
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYTVKVQ 7
           SYT+KV+
Sbjct: 348 SYTLKVE 354



>XP_005255817
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYTVKVQ 7
           SYT+KV+
Sbjct: 350 SYTLKVE 356



>XP_005255816
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYTVKVQ 7
           SYT+KV+
Sbjct: 350 SYTLKVE 356



>NP_071927
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YTVKVQRE 9
           YT KVQ E
Sbjct: 95  YTAKVQVE 102



>NP_114097
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYTVKVQ 7
           SYT+KV+
Sbjct: 348 SYTLKVE 354



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.119    0.293 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 429,490
Number of extensions: 659
Number of successful extensions: 34
Number of sequences better than 10000.0: 34
Number of HSP's gapped: 34
Number of HSP's successfully gapped: 34
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)