Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              20     509
XP_006718908                                                           20     509
XP_005271621                                                           20     509
XP_006718907                                                           20     509
XP_006718906                                                           20     509
XP_005271619                                                           20     509
XP_005271618                                                           20     509
NP_443084                                                              17    3301
NP_775764                                                              16    7355
NP_079002                                                              16    7355
NP_068749                                                              16    7355
NP_001257514                                                           16    7355
NP_001257513                                                           16    7355
XP_005250581                                                           16    7355
NP_001152994                                                           15    9605
NP_001092739                                                           15    9605
NP_001070146                                                           15    9605
NP_112495                                                              15    9605
NP_001254645                                                           15    9605
NP_001274462                                                           15    9605
NP_001138876                                                           15    9605
NP_001164376                                                           15    9605
NP_001124385                                                           15    9605
NP_001274463                                                           15    9605
NP_001274461                                                           15    9605
NP_149973                                                              15    9605
NP_001070817                                                           15    9605
NP_001265874                                                           15    9605
NP_060962                                                              15    9605
NP_009084                                                              15    9605
NP_001230967                                                           15    9605
NP_009070                                                              15    9605
NP_689839                                                              15    9605
XP_005260203                                                           15    9605
XP_006722813                                                           15    9605
XP_006722795                                                           15    9605
XP_006722794                                                           15    9605
XP_005259922                                                           15    9605
XP_005259921                                                           15    9605
XP_005255179                                                           15    9605
XP_006716431                                                           15    9605
XP_006716167                                                           15    9605
XP_006716022                                                           15    9605
XP_006715924                                                           15    9605
XP_006715904                                                           15    9605
XP_006715903                                                           15    9605
NP_848653                                                              15    9605
NP_066971                                                              15    9605
>NP_000042
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SYQKIILAI 9
            SYQKI+LAI
Sbjct: 1414 SYQKILLAI 1422
>XP_006718908
          Length = 1708

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  SYQKIILAI 9
          SYQKI+LAI
Sbjct: 66 SYQKILLAI 74
>XP_005271621
          Length = 2708

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SYQKIILAI 9
            SYQKI+LAI
Sbjct: 1066 SYQKILLAI 1074
>XP_006718907
          Length = 3050

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SYQKIILAI 9
            SYQKI+LAI
Sbjct: 1408 SYQKILLAI 1416
>XP_006718906
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SYQKIILAI 9
            SYQKI+LAI
Sbjct: 1414 SYQKILLAI 1422
>XP_005271619
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SYQKIILAI 9
            SYQKI+LAI
Sbjct: 1414 SYQKILLAI 1422
>XP_005271618
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SYQKIILAI 9
            SYQKI+LAI
Sbjct: 1414 SYQKILLAI 1422
>NP_443084
          Length = 463

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           SYQK+IL
Sbjct: 103 SYQKVIL 109
>NP_775764
          Length = 773

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  YQKIIL 7
          YQKIIL
Sbjct: 90 YQKIIL 95
>NP_079002
          Length = 822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   YQKIIL 7
           YQKIIL
Sbjct: 696 YQKIIL 701
>NP_068749
          Length = 792

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   YQKIILA 8
           YQ+IILA
Sbjct: 687 YQEIILA 693
>NP_001257514
          Length = 830

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   YQKIIL 7
           YQKIIL
Sbjct: 704 YQKIIL 709
>NP_001257513
          Length = 781

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   YQKIIL 7
           YQKIIL
Sbjct: 655 YQKIIL 660
>XP_005250581
          Length = 451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   YQKIILA 8
           YQ+IILA
Sbjct: 346 YQEIILA 352
>NP_001152994
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 94  SFQKVIL 100
>NP_001092739
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 94  SFQKVIL 100
>NP_001070146
          Length = 774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 103 SFQKVIL 109
>NP_112495
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 94  SFQKVIL 100
>NP_001254645
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 94  SFQKVIL 100
>NP_001274462
          Length = 510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SYQKIIL 7
          S+QK+IL
Sbjct: 18 SFQKVIL 24
>NP_001138876
          Length = 412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SYQKIIL 7
          S+QK+IL
Sbjct: 62 SFQKVIL 68
>NP_001164376
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 94  SFQKVIL 100
>NP_001124385
          Length = 126

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 94  SFQKVIL 100
>NP_001274463
          Length = 510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SYQKIIL 7
          S+QK+IL
Sbjct: 18 SFQKVIL 24
>NP_001274461
          Length = 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SYQKIIL 7
          S+QK+IL
Sbjct: 62 SFQKVIL 68
>NP_149973
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 94  SFQKVIL 100
>NP_001070817
          Length = 466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SYQKIIL 7
          S+QK+IL
Sbjct: 62 SFQKVIL 68
>NP_001265874
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   SYQKII 6
           SYQK+I
Sbjct: 300 SYQKVI 305
>NP_060962
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   SYQKII 6
           SYQK+I
Sbjct: 289 SYQKVI 294
>NP_009084
          Length = 1280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 94  SFQKVIL 100
>NP_001230967
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 94  SFQKVIL 100
>NP_009070
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SYQKIIL 7
          S+QK+IL
Sbjct: 25 SFQKVIL 31
>NP_689839
          Length = 586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 94  SFQKVIL 100
>XP_005260203
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SYQKIIL 7
          S+QK+IL
Sbjct: 18 SFQKVIL 24
>XP_006722813
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 94  SFQKVIL 100
>XP_006722795
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 104 SFQKVIL 110
>XP_006722794
          Length = 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 104 SFQKVIL 110
>XP_005259922
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SYQKIIL 7
          S+QK+IL
Sbjct: 30 SFQKVIL 36
>XP_005259921
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 104 SFQKVIL 110
>XP_005255179
          Length = 128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 96  SFQKVIL 102
>XP_006716431
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   SYQKII 6
           SYQK+I
Sbjct: 289 SYQKVI 294
>XP_006716167
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 94  SFQKVIL 100
>XP_006716022
          Length = 489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SYQKIIL 7
          S+QK+IL
Sbjct: 62 SFQKVIL 68
>XP_006715924
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 94  SFQKVIL 100
>XP_006715904
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SYQKIIL 7
          S+QK+IL
Sbjct: 62 SFQKVIL 68
>XP_006715903
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SYQKIIL 7
          S+QK+IL
Sbjct: 62 SFQKVIL 68
>NP_848653
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 103 SFQKVIL 109
>NP_066971
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SYQKIIL 7
           S+QK+IL
Sbjct: 127 SFQKVIL 133
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.144    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 390,785
Number of extensions: 664
Number of successful extensions: 48
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 48
Number of HSP's successfully gapped: 48
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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