Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           19     869
NP_036462                                                              19     869
NP_001243397                                                           19     869
XP_005269721                                                           19     869
NP_619542                                                              16    5631
NP_009003                                                              16    5631
NP_001269485                                                           16    5631
NP_001269486                                                           16    5631
NP_001269487                                                           16    5631
XP_005274600                                                           16    5631
XP_005247137                                                           16    5631
NP_060499                                                              16    5631
NP_689697                                                              16    7355
XP_005258621                                                           16    7355
XP_006723112                                                           16    7355
XP_006723111                                                           16    7355
XP_006723110                                                           16    7355
XP_006723109                                                           16    7355
NP_659422                                                              16    7355
NP_071923                                                              16    7355
NP_001274174                                                           15    9605
NP_001091884                                                           15    9605
NP_036418                                                              15    9605
NP_001135891                                                           15    9605
NP_001019907                                                           15    9605
NP_001135897                                                           15    9605
NP_001135893                                                           15    9605
NP_001135898                                                           15    9605
NP_940886                                                              15    9605
NP_079516                                                              15    9605
NP_001135895                                                           15    9605
NP_001135892                                                           15    9605
NP_001135894                                                           15    9605
NP_001135904                                                           15    9605
NP_001135903                                                           15    9605
NP_001135902                                                           15    9605
NP_001135901                                                           15    9605
NP_001135899                                                           15    9605
NP_001135890                                                           15    9605
NP_008896                                                              15    9605
NP_787084                                                              15    9605
XP_005258398                                                           15    9605
XP_005254757                                                           15    9605
XP_005254756                                                           15    9605
XP_006719430                                                           15    9605
XP_006719429                                                           15    9605
XP_006719428                                                           15    9605
XP_005253933                                                           15    9605
XP_005265070                                                           15    9605
XP_005265069                                                           15    9605
XP_005265068                                                           15    9605
NP_001135896                                                           15    9605
NP_001135900                                                           15    9605
NP_001084                                                              15    9605
YP_003024038                                                           15    9605
>NP_001243398
          Length = 1781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SYANSASL 8
            SYANSASL
Sbjct: 1550 SYANSASL 1557
>NP_036462
          Length = 2073

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SYANSASL 8
            SYANSASL
Sbjct: 1842 SYANSASL 1849
>NP_001243397
          Length = 1890

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SYANSASL 8
            SYANSASL
Sbjct: 1659 SYANSASL 1666
>XP_005269721
          Length = 2073

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SYANSASL 8
            SYANSASL
Sbjct: 1842 SYANSASL 1849
>NP_619542
          Length = 1041

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SYANSAS 7
           SYANS+S
Sbjct: 440 SYANSSS 446
>NP_009003
          Length = 414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  YANSASLF 9
          YAN  SLF
Sbjct: 88 YANRTSLF 95
>NP_001269485
          Length = 414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  YANSASLF 9
          YAN  SLF
Sbjct: 88 YANRTSLF 95
>NP_001269486
          Length = 414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  YANSASLF 9
          YAN  SLF
Sbjct: 88 YANRTSLF 95
>NP_001269487
          Length = 397

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  YANSASLF 9
          YAN  SLF
Sbjct: 88 YANRTSLF 95
>XP_005274600
          Length = 1059

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SYANSAS 7
           SYANS+S
Sbjct: 458 SYANSSS 464
>XP_005247137
          Length = 414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  YANSASLF 9
          YAN  SLF
Sbjct: 88 YANRTSLF 95
>NP_060499
          Length = 272

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SYANSASLF 9
          +Y NS SLF
Sbjct: 9  AYVNSHSLF 17
>NP_689697
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SYANSASLF 9
           SY NS+S F
Sbjct: 173 SYGNSSSHF 181
>XP_005258621
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SYANSASLF 9
          SY NS+S F
Sbjct: 14 SYGNSSSHF 22
>XP_006723112
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SYANSASLF 9
           SY NS+S F
Sbjct: 173 SYGNSSSHF 181
>XP_006723111
          Length = 710

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SYANSASLF 9
           SY NS+S F
Sbjct: 197 SYGNSSSHF 205
>XP_006723110
          Length = 710

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SYANSASLF 9
           SY NS+S F
Sbjct: 197 SYGNSSSHF 205
>XP_006723109
          Length = 710

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SYANSASLF 9
           SY NS+S F
Sbjct: 197 SYGNSSSHF 205
>NP_659422
          Length = 781

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SYANSASL 8
           SY NSA L
Sbjct: 181 SYGNSAKL 188
>NP_071923
          Length = 819

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SYANSASL 8
           SY NSA L
Sbjct: 181 SYGNSAKL 188
>NP_001274174
          Length = 157

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SYANSASL 8
          +YAN ASL
Sbjct: 43 NYANVASL 50
>NP_001091884
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SYANSASL 8
          +YAN ASL
Sbjct: 43 NYANVASL 50
>NP_036418
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_001135891
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_001019907
          Length = 534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SYANSASLF 9
          +YAN  +LF
Sbjct: 88 AYANRTALF 96

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SYANSASLF 9
           +YAN  +LF
Sbjct: 306 AYANRTALF 314
>NP_001135897
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_001135893
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_001135898
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_940886
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SYANSASL 8
          +YAN ASL
Sbjct: 43 NYANVASL 50
>NP_079516
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SYANSASLF 9
          +YAN  +LF
Sbjct: 88 AYANRTALF 96
>NP_001135895
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_001135892
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_001135894
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_001135904
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_001135903
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_001135902
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_001135901
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_001135899
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_001135890
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_008896
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SYANSASLF 9
           SY+ S++LF
Sbjct: 343 SYSQSSNLF 351
>NP_787084
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SYANSASL 8
          +YAN ASL
Sbjct: 43 NYANVASL 50
>XP_005258398
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SYANSASLF 9
           SY+ S++LF
Sbjct: 343 SYSQSSNLF 351
>XP_005254757
          Length = 534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SYANSASLF 9
          +YAN  +LF
Sbjct: 88 AYANRTALF 96

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SYANSASLF 9
           +YAN  +LF
Sbjct: 306 AYANRTALF 314
>XP_005254756
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SYANSASLF 9
           +YAN  +LF
Sbjct: 111 AYANRTALF 119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SYANSASLF 9
           +YAN  +LF
Sbjct: 329 AYANRTALF 337
>XP_006719430
          Length = 2256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   YANSASLF 9
           Y N+ SLF
Sbjct: 308 YGNAVSLF 315
>XP_006719429
          Length = 2395

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   YANSASLF 9
           Y N+ SLF
Sbjct: 510 YGNAVSLF 517
>XP_006719428
          Length = 2458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   YANSASLF 9
           Y N+ SLF
Sbjct: 510 YGNAVSLF 517
>XP_005253933
          Length = 2458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   YANSASLF 9
           Y N+ SLF
Sbjct: 510 YGNAVSLF 517
>XP_005265070
          Length = 384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SYANSASL 8
          +YAN ASL
Sbjct: 43 NYANVASL 50
>XP_005265069
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SYANSASL 8
          +YAN ASL
Sbjct: 43 NYANVASL 50
>XP_005265068
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SYANSASL 8
          +YAN ASL
Sbjct: 43 NYANVASL 50
>NP_001135896
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_001135900
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NSASLF 9
           NSASLF
Sbjct: 266 NSASLF 271
>NP_001084
          Length = 2458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   YANSASLF 9
           Y N+ SLF
Sbjct: 510 YGNAVSLF 517
>YP_003024038
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  YANSASLF 9
          +AN AS+F
Sbjct: 83 HANGASMF 90
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.113    0.287 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 340,832
Number of extensions: 362
Number of successful extensions: 58
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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