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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              20     299
NP_003599                                                              17    3301
NP_003276                                                              17    4312
XP_005249698                                                           17    4312
NP_001129396                                                           17    4312
NP_000246                                                              16    5631
NP_689551                                                              16    5631
XP_005249200                                                           16    5631
NP_001129173                                                           16    7355
NP_001129172                                                           16    7355
NP_001129171                                                           16    7355
NP_663723                                                              16    7355
NP_003397                                                              16    7355
NP_001129174                                                           16    7355
NP_001125                                                              16    7355
NP_001181887                                                           16    7355
NP_036260                                                              16    7355
NP_066292                                                              16    7355
XP_005256682                                                           16    7355
XP_005276976                                                           16    7355
XP_005251120                                                           16    7355
XP_005251119                                                           16    7355
XP_005251118                                                           16    7355
XP_005251117                                                           16    7355
NP_065077                                                              15    9605
NP_071374                                                              15    9605
NP_001271200                                                           15    9605
NP_006819                                                              15    9605
NP_114141                                                              15    9605
NP_001073977                                                           15    9605
XP_006718987                                                           15    9605
XP_005251496                                                           15    9605
XP_005251482                                                           15    9605
XP_005251483                                                           15    9605
XP_005264750                                                           15    9605
NP_061720                                                              15    9605
NP_057114                                                              15    9605

>NP_443179
          Length = 2170

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SVTEQGRY 8
           SVTEQGRY
Sbjct: 442 SVTEQGRY 449



>NP_003599
          Length = 337

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VTEQGRYN 9
           VTE GRY+
Sbjct: 293 VTETGRYD 300



>NP_003276
          Length = 1358

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VTEQGRY 8
            +T QGRY
Sbjct: 1218 ITSQGRY 1224



>XP_005249698
          Length = 1044

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   VTEQGRYN 9
           + E+G+YN
Sbjct: 320 IVEEGKYN 327



>NP_001129396
          Length = 1590

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   VTEQGRYN 9
           + E+G+YN
Sbjct: 866 IVEEGKYN 873



>NP_000246
          Length = 750

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SVTEQGRYN 9
           S+TEQ  YN
Sbjct: 357 SLTEQDPYN 365



>NP_689551
          Length = 167

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VTEQGRY 8
           VT++GRY
Sbjct: 111 VTDKGRY 117



>XP_005249200
          Length = 750

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SVTEQGRYN 9
           S+TEQ  YN
Sbjct: 357 SLTEQDPYN 365



>NP_001129173
          Length = 245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SVTEQG 6
          SVTEQG
Sbjct: 28 SVTEQG 33



>NP_001129172
          Length = 245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SVTEQG 6
          SVTEQG
Sbjct: 28 SVTEQG 33



>NP_001129171
          Length = 245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SVTEQG 6
          SVTEQG
Sbjct: 28 SVTEQG 33



>NP_663723
          Length = 245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SVTEQG 6
          SVTEQG
Sbjct: 28 SVTEQG 33



>NP_003397
          Length = 245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SVTEQG 6
          SVTEQG
Sbjct: 28 SVTEQG 33



>NP_001129174
          Length = 245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SVTEQG 6
          SVTEQG
Sbjct: 28 SVTEQG 33



>NP_001125
          Length = 609

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVTEQGRYN 9
           S +E+GR+N
Sbjct: 115 SQSEEGRHN 123



>NP_001181887
          Length = 433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   VTEQGRY 8
           VTE+G Y
Sbjct: 237 VTEEGEY 243



>NP_036260
          Length = 919

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TEQGRYN 9
           TE GRY+
Sbjct: 669 TENGRYS 675



>NP_066292
          Length = 433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   VTEQGRY 8
           VTE+G Y
Sbjct: 237 VTEEGEY 243



>XP_005256682
          Length = 433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   VTEQGRY 8
           VTE+G Y
Sbjct: 237 VTEEGEY 243



>XP_005276976
          Length = 535

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   VTEQGRY 8
           VTE+G Y
Sbjct: 339 VTEEGEY 345



>XP_005251120
          Length = 245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SVTEQG 6
          SVTEQG
Sbjct: 28 SVTEQG 33



>XP_005251119
          Length = 245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SVTEQG 6
          SVTEQG
Sbjct: 28 SVTEQG 33



>XP_005251118
          Length = 245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SVTEQG 6
          SVTEQG
Sbjct: 28 SVTEQG 33



>XP_005251117
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SVTEQG 6
           SVTEQG
Sbjct: 167 SVTEQG 172



>NP_065077
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SVTEQGRY 8
           ++TE+GR+
Sbjct: 372 TMTEEGRF 379



>NP_071374
          Length = 111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SVTEQGRYN 9
          +VT+Q  YN
Sbjct: 15 NVTKQDNYN 23



>NP_001271200
          Length = 731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SVTEQGRYN 9
          +VT+Q  YN
Sbjct: 15 NVTKQDNYN 23



>NP_006819
          Length = 2202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SVTEQGRYN 9
          +VT+Q  YN
Sbjct: 15 NVTKQDNYN 23



>NP_114141
          Length = 5635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VTEQGRY 8
            VT+ GRY
Sbjct: 3775 VTDTGRY 3781



>NP_001073977
          Length = 607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   TEQGRYN 9
           T QG YN
Sbjct: 513 THQGSYN 519



>XP_006718987
          Length = 401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SVTEQGR 7
          SVT++GR
Sbjct: 16 SVTQEGR 22



>XP_005251496
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SVTEQGRYN 9
           ++ E G+YN
Sbjct: 641 TIYENGKYN 649



>XP_005251482
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SVTEQGRY 8
           ++TE+GR+
Sbjct: 372 TMTEEGRF 379



>XP_005251483
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SVTEQGRY 8
           ++TE+GR+
Sbjct: 372 TMTEEGRF 379



>XP_005264750
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVTEQGR 7
           SVT++GR
Sbjct: 527 SVTQEGR 533



>NP_061720
          Length = 4024

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    VTEQGRYN 9
            V E GR+N
Sbjct: 3786 VQEMGRFN 3793



>NP_057114
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVTEQGR 7
           SVT++GR
Sbjct: 527 SVTQEGR 533



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.120    0.322 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 573,757
Number of extensions: 891
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)