Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              18    1482
NP_001120972                                                           18    1482
XP_006716054                                                           18    1482
XP_006716053                                                           18    1482
XP_006716052                                                           18    1482
XP_006716051                                                           18    1482
NP_570843                                                              17    2528
NP_001128529                                                           17    2528
NP_001137357                                                           16    7355
NP_001137358                                                           16    7355
NP_001231921                                                           16    7355
NP_001231919                                                           16    7355
NP_002471                                                              16    7355
NP_060959                                                              16    7355
XP_005268948                                                           16    7355
XP_005268946                                                           16    7355
XP_005268944                                                           16    7355
XP_005268945                                                           16    7355
XP_005268943                                                           16    7355
XP_005268942                                                           16    7355
XP_005245394                                                           16    7355
XP_005245393                                                           16    7355
XP_006711515                                                           16    7355
XP_006711514                                                           16    7355
XP_006711513                                                           16    7355
NP_490647                                                              15    9605
NP_005485                                                              15    9605
NP_001244119                                                           15    9605
NP_742017                                                              15    9605
XP_006716259                                                           15    9605
XP_006716258                                                           15    9605
XP_005250789                                                           15    9605
XP_005250788                                                           15    9605
XP_005250787                                                           15    9605
XP_005250786                                                           15    9605
XP_006716257                                                           15    9605
XP_005250785                                                           15    9605
XP_005250784                                                           15    9605
XP_005250783                                                           15    9605
XP_006715886                                                           15    9605
XP_005249573                                                           15    9605
XP_005249572                                                           15    9605
>NP_000236
          Length = 1390

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVSSTTEMV 9
           SVS TTEMV
Sbjct: 988 SVSPTTEMV 996
>NP_001120972
          Length = 1408

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SVSSTTEMV 9
            SVS TTEMV
Sbjct: 1006 SVSPTTEMV 1014
>XP_006716054
          Length = 960

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVSSTTEMV 9
           SVS TTEMV
Sbjct: 558 SVSPTTEMV 566
>XP_006716053
          Length = 960

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVSSTTEMV 9
           SVS TTEMV
Sbjct: 558 SVSPTTEMV 566
>XP_006716052
          Length = 1409

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SVSSTTEMV 9
            SVS TTEMV
Sbjct: 1007 SVSPTTEMV 1015
>XP_006716051
          Length = 1427

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SVSSTTEMV 9
            SVS TTEMV
Sbjct: 1025 SVSPTTEMV 1033
>NP_570843
          Length = 581

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SVSSTTEM 8
           SVSSTTE+
Sbjct: 501 SVSSTTEL 508
>NP_001128529
          Length = 587

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SVSSTTEM 8
           SVSSTTE+
Sbjct: 507 SVSSTTEL 514
>NP_001137357
          Length = 1030

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SVSSTTEM 8
           +VSSTTE+
Sbjct: 655 TVSSTTEV 662
>NP_001137358
          Length = 943

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SVSSTTEM 8
           +VSSTTE+
Sbjct: 568 TVSSTTEV 575
>NP_001231921
          Length = 974

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SVSSTTEM 8
           +VSSTTE+
Sbjct: 599 TVSSTTEV 606
>NP_001231919
          Length = 995

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SVSSTTEM 8
           +VSSTTE+
Sbjct: 655 TVSSTTEV 662
>NP_002471
          Length = 1030

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SVSSTTEM 8
           +VSSTTE+
Sbjct: 655 TVSSTTEV 662
>NP_060959
          Length = 2964

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VSSTTEMV 9
           +SSTTE++
Sbjct: 585 LSSTTELI 592
>XP_005268948
          Length = 990

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SVSSTTEM 8
           +VSSTTE+
Sbjct: 599 TVSSTTEV 606
>XP_005268946
          Length = 999

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SVSSTTEM 8
           +VSSTTE+
Sbjct: 655 TVSSTTEV 662
>XP_005268944
          Length = 1005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SVSSTTEM 8
           +VSSTTE+
Sbjct: 655 TVSSTTEV 662
>XP_005268945
          Length = 1005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SVSSTTEM 8
           +VSSTTE+
Sbjct: 655 TVSSTTEV 662
>XP_005268943
          Length = 1034

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SVSSTTEM 8
           +VSSTTE+
Sbjct: 643 TVSSTTEV 650
>XP_005268942
          Length = 1046

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SVSSTTEM 8
           +VSSTTE+
Sbjct: 655 TVSSTTEV 662
>XP_005245394
          Length = 1741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VSSTTEMV 9
           +SSTTE++
Sbjct: 585 LSSTTELI 592
>XP_005245393
          Length = 2663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VSSTTEMV 9
           +SSTTE++
Sbjct: 585 LSSTTELI 592
>XP_006711515
          Length = 2904

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VSSTTEMV 9
           +SSTTE++
Sbjct: 585 LSSTTELI 592
>XP_006711514
          Length = 2964

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VSSTTEMV 9
           +SSTTE++
Sbjct: 585 LSSTTELI 592
>XP_006711513
          Length = 2964

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VSSTTEMV 9
           +SSTTE++
Sbjct: 585 LSSTTELI 592
>NP_490647
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SVSSTTEMV 9
           S+S++T+MV
Sbjct: 190 SISTSTKMV 198
>NP_005485
          Length = 241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SVSSTTEMV 9
           S+S++T+MV
Sbjct: 190 SISTSTKMV 198
>NP_001244119
          Length = 999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVSSTTE 7
           +VSSTTE
Sbjct: 899 NVSSTTE 905
>NP_742017
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVSSTTE 7
           +VSSTTE
Sbjct: 899 NVSSTTE 905
>XP_006716259
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVSSTTE 7
           +VSSTTE
Sbjct: 899 NVSSTTE 905
>XP_006716258
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVSSTTE 7
           +VSSTTE
Sbjct: 899 NVSSTTE 905
>XP_005250789
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVSSTTE 7
           +VSSTTE
Sbjct: 899 NVSSTTE 905
>XP_005250788
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVSSTTE 7
           +VSSTTE
Sbjct: 899 NVSSTTE 905
>XP_005250787
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVSSTTE 7
           +VSSTTE
Sbjct: 899 NVSSTTE 905
>XP_005250786
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVSSTTE 7
           +VSSTTE
Sbjct: 899 NVSSTTE 905
>XP_006716257
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVSSTTE 7
           +VSSTTE
Sbjct: 899 NVSSTTE 905
>XP_005250785
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVSSTTE 7
           +VSSTTE
Sbjct: 899 NVSSTTE 905
>XP_005250784
          Length = 1190

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SVSSTTE 7
            +VSSTTE
Sbjct: 1105 NVSSTTE 1111
>XP_005250783
          Length = 1249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SVSSTTE 7
            +VSSTTE
Sbjct: 1164 NVSSTTE 1170
>XP_006715886
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SVSSTTEMV 9
           S+S++T+MV
Sbjct: 190 SISTSTKMV 198
>XP_005249573
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SVSSTTEMV 9
           S+S++T+MV
Sbjct: 190 SISTSTKMV 198
>XP_005249572
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SVSSTTEMV 9
           S+S++T+MV
Sbjct: 190 SISTSTKMV 198
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.285   0.0926    0.191 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 292,274
Number of extensions: 481
Number of successful extensions: 42
Number of sequences better than 10000.0: 42
Number of HSP's gapped: 42
Number of HSP's successfully gapped: 42
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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