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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000213                                                              18    1135
NP_001087241                                                           18    1135
XP_005265799                                                           18    1135
XP_005265798                                                           18    1135
XP_005265797                                                           18    1135
NP_620132                                                              17    3301
NP_001166983                                                           17    3301
XP_005252359                                                           17    3301
NP_037484                                                              16    5631
NP_001074445                                                           16    5631
NP_055221                                                              16    5631
XP_005267010                                                           16    5631
NP_079285                                                              15    9605
NP_000055                                                              15    9605
NP_056125                                                              15    9605
NP_003706                                                              15    9605
NP_001276978                                                           15    9605
NP_003817                                                              15    9605
NP_065868                                                              15    9605
NP_077285                                                              15    9605
NP_001154999                                                           15    9605
XP_005273518                                                           15    9605
XP_006716381                                                           15    9605
XP_006714460                                                           15    9605
XP_006714459                                                           15    9605
XP_005265845                                                           15    9605
XP_006714118                                                           15    9605
XP_005247738                                                           15    9605
XP_005247737                                                           15    9605
XP_006713778                                                           15    9605

>NP_000213
          Length = 976

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VQLIEKQI 9
           VQLIEKQI
Sbjct: 921 VQLIEKQI 928



>NP_001087241
          Length = 972

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VQLIEKQI 9
           VQLIEKQI
Sbjct: 917 VQLIEKQI 924



>XP_005265799
          Length = 973

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VQLIEKQI 9
           VQLIEKQI
Sbjct: 918 VQLIEKQI 925



>XP_005265798
          Length = 976

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VQLIEKQI 9
           VQLIEKQI
Sbjct: 921 VQLIEKQI 928



>XP_005265797
          Length = 977

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VQLIEKQI 9
           VQLIEKQI
Sbjct: 922 VQLIEKQI 929



>NP_620132
          Length = 262

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SVQLIEKQI 9
           +++LIEKQI
Sbjct: 230 TIRLIEKQI 238



>NP_001166983
          Length = 210

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SVQLIEKQI 9
           +++LIEKQI
Sbjct: 178 TIRLIEKQI 186



>XP_005252359
          Length = 283

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SVQLIEKQI 9
           +++LIEKQI
Sbjct: 251 TIRLIEKQI 259



>NP_037484
          Length = 958

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLIEKQI 9
           QL+EKQI
Sbjct: 754 QLLEKQI 760



>NP_001074445
          Length = 958

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLIEKQI 9
           QL+EKQI
Sbjct: 754 QLLEKQI 760



>NP_055221
          Length = 557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVQLIEKQI 9
           S QL+EKQ+
Sbjct: 274 SDQLLEKQV 282



>XP_005267010
          Length = 958

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLIEKQI 9
           QL+EKQI
Sbjct: 754 QLLEKQI 760



>NP_079285
          Length = 1140

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VQLIEKQI 9
           V+L+EK+I
Sbjct: 925 VELLEKEI 932



>NP_000055
          Length = 1663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVQLIEKQI 9
           SVQL EK++
Sbjct: 672 SVQLTEKRM 680



>NP_056125
          Length = 1047

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVQLIEKQI 9
           SVQ +EK++
Sbjct: 165 SVQQVEKEL 173



>NP_003706
          Length = 962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLIEKQI 9
           QLIEK+I
Sbjct: 566 QLIEKRI 572



>NP_001276978
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLIEKQI 9
           QLIEK+I
Sbjct: 577 QLIEKRI 583



>NP_003817
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVQLIEK 7
           +VQLIEK
Sbjct: 94  AVQLIEK 100



>NP_065868
          Length = 936

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   QLIEKQ 8
           QLIEKQ
Sbjct: 561 QLIEKQ 566



>NP_077285
          Length = 429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VQLIEKQI 9
           VQ++E+QI
Sbjct: 296 VQMLEQQI 303



>NP_001154999
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VQLIEKQI 9
           VQ++E+QI
Sbjct: 189 VQMLEQQI 196



>XP_005273518
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVQLIEKQI 9
           SVQ +EK++
Sbjct: 165 SVQQVEKEL 173



>XP_006716381
          Length = 1014

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVQLIEKQI 9
           SVQ +EK++
Sbjct: 132 SVQQVEKEL 140



>XP_006714460
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLIEKQI 9
           QLIEK+I
Sbjct: 570 QLIEKRI 576



>XP_006714459
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLIEKQI 9
           QLIEK+I
Sbjct: 573 QLIEKRI 579



>XP_005265845
          Length = 783

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VQLIEKQI 9
           V+L+EK+I
Sbjct: 568 VELLEKEI 575



>XP_006714118
          Length = 1129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VQLIEKQI 9
           V+L+EK+I
Sbjct: 914 VELLEKEI 921



>XP_005247738
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   QLIEKQ 8
           QLIEKQ
Sbjct: 240 QLIEKQ 245



>XP_005247737
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   QLIEKQ 8
           QLIEKQ
Sbjct: 539 QLIEKQ 544



>XP_006713778
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   QLIEKQ 8
           QLIEKQ
Sbjct: 548 QLIEKQ 553



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.132    0.291 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 432,932
Number of extensions: 632
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)