Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           20     299
NP_036462                                                              20     299
NP_001243397                                                           20     299
XP_005269721                                                           20     299
NP_872363                                                              17    2528
XP_005271570                                                           17    2528
XP_005271569                                                           17    2528
XP_006718878                                                           17    2528
XP_005271568                                                           17    2528
NP_003292                                                              17    4312
NP_067629                                                              16    5631
NP_001003827                                                           16    5631
NP_001003819                                                           16    5631
NP_001804                                                              16    7355
NP_001273663                                                           16    7355
NP_055309                                                              16    7355
NP_945347                                                              16    7355
XP_006724029                                                           16    7355
XP_005260981                                                           16    7355
XP_006724028                                                           16    7355
XP_005260979                                                           16    7355
XP_005260978                                                           16    7355
XP_005260977                                                           16    7355
XP_006721103                                                           16    7355
XP_005255314                                                           16    7355
XP_006721102                                                           16    7355
XP_005255313                                                           16    7355
XP_005255312                                                           16    7355
XP_006721101                                                           16    7355
XP_005255311                                                           16    7355
XP_005255310                                                           16    7355
NP_005566                                                              15    9605
NP_787116                                                              15    9605
NP_001240628                                                           15    9605
NP_001092882                                                           15    9605
NP_006757                                                              15    9605
NP_001092883                                                           15    9605
NP_775821                                                              15    9605
NP_002130                                                              15    9605
NP_001156008                                                           15    9605
NP_001155907                                                           15    9605
NP_062556                                                              15    9605
NP_001240630                                                           15    9605
NP_001006600                                                           15    9605
NP_061165                                                              15    9605
NP_001240627                                                           15    9605
NP_001240626                                                           15    9605
XP_006717495                                                           15    9605
XP_006717494                                                           15    9605
XP_006717493                                                           15    9605
XP_006717492                                                           15    9605
XP_006717490                                                           15    9605
XP_006717489                                                           15    9605
XP_006717488                                                           15    9605
XP_006717487                                                           15    9605
XP_006717486                                                           15    9605
XP_005251455                                                           15    9605
XP_005251456                                                           15    9605
XP_005251454                                                           15    9605
XP_005273706                                                           15    9605
XP_006714723                                                           15    9605
XP_005248613                                                           15    9605
XP_005248612                                                           15    9605
XP_005248611                                                           15    9605
NP_001009894                                                           15    9605
>NP_001243398
          Length = 1781

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SVNMNMNT 8
            SVNMNMNT
Sbjct: 1689 SVNMNMNT 1696
>NP_036462
          Length = 2073

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SVNMNMNT 8
            SVNMNMNT
Sbjct: 1981 SVNMNMNT 1988
>NP_001243397
          Length = 1890

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SVNMNMNT 8
            SVNMNMNT
Sbjct: 1798 SVNMNMNT 1805
>XP_005269721
          Length = 2073

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SVNMNMNT 8
            SVNMNMNT
Sbjct: 1981 SVNMNMNT 1988
>NP_872363
          Length = 1499

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVNMNMN 7
           +VNMNMN
Sbjct: 775 NVNMNMN 781

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNMNMNTS 9
           ++NMNMN +
Sbjct: 769 NLNMNMNVN 777

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNMNMN 7
           ++NMNMN
Sbjct: 777 NMNMNMN 783
>XP_005271570
          Length = 1462

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVNMNMN 7
           +VNMNMN
Sbjct: 738 NVNMNMN 744

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNMNMNTS 9
           ++NMNMN +
Sbjct: 732 NLNMNMNVN 740

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNMNMN 7
           ++NMNMN
Sbjct: 740 NMNMNMN 746
>XP_005271569
          Length = 1462

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVNMNMN 7
           +VNMNMN
Sbjct: 738 NVNMNMN 744

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNMNMNTS 9
           ++NMNMN +
Sbjct: 732 NLNMNMNVN 740

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNMNMN 7
           ++NMNMN
Sbjct: 740 NMNMNMN 746
>XP_006718878
          Length = 1499

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVNMNMN 7
           +VNMNMN
Sbjct: 775 NVNMNMN 781

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNMNMNTS 9
           ++NMNMN +
Sbjct: 769 NLNMNMNVN 777

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNMNMN 7
           ++NMNMN
Sbjct: 777 NMNMNMN 783
>XP_005271568
          Length = 1499

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVNMNMN 7
           +VNMNMN
Sbjct: 775 NVNMNMN 781

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNMNMNTS 9
           ++NMNMN +
Sbjct: 769 NLNMNMNVN 777

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNMNMN 7
           ++NMNMN
Sbjct: 777 NMNMNMN 783
>NP_003292
          Length = 398

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNMNMNTS 9
           + N+N+NTS
Sbjct: 242 NTNLNVNTS 250
>NP_067629
          Length = 488

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNMNMN 7
           SVN+N+N
Sbjct: 307 SVNLNLN 313
>NP_001003827
          Length = 488

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNMNMN 7
           SVN+N+N
Sbjct: 307 SVNLNLN 313
>NP_001003819
          Length = 842

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNMNMN 7
           SVN+N+N
Sbjct: 661 SVNLNLN 667
>NP_001804
          Length = 2701

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SVNMNMNT 8
           +VNMN++T
Sbjct: 955 TVNMNIDT 962
>NP_001273663
          Length = 2580

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SVNMNMNT 8
           +VNMN++T
Sbjct: 930 TVNMNIDT 937
>NP_055309
          Length = 1962

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SVNMNMNT 8
            +VNM+MN+
Sbjct: 1520 NVNMDMNS 1527
>NP_945347
          Length = 481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SVNMNMNT 8
          S+N+N NT
Sbjct: 86 SLNVNFNT 93
>XP_006724029
          Length = 398

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SVNMNMNT 8
           S+N+N NT
Sbjct: 94  SLNVNFNT 101
>XP_005260981
          Length = 404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SVNMNMNT 8
           S+N+N NT
Sbjct: 94  SLNVNFNT 101
>XP_006724028
          Length = 404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SVNMNMNT 8
           S+N+N NT
Sbjct: 94  SLNVNFNT 101
>XP_005260979
          Length = 459

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SVNMNMNT 8
           S+N+N NT
Sbjct: 94  SLNVNFNT 101
>XP_005260978
          Length = 483

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SVNMNMNT 8
           S+N+N NT
Sbjct: 94  SLNVNFNT 101
>XP_005260977
          Length = 489

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SVNMNMNT 8
           S+N+N NT
Sbjct: 94  SLNVNFNT 101
>XP_006721103
          Length = 1597

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SVNMNMNT 8
            +VNM+MN+
Sbjct: 1488 NVNMDMNS 1495
>XP_005255314
          Length = 1709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SVNMNMNT 8
            +VNM+MN+
Sbjct: 1267 NVNMDMNS 1274
>XP_006721102
          Length = 1820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SVNMNMNT 8
            +VNM+MN+
Sbjct: 1378 NVNMDMNS 1385
>XP_005255313
          Length = 1822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SVNMNMNT 8
            +VNM+MN+
Sbjct: 1380 NVNMDMNS 1387
>XP_005255312
          Length = 1871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SVNMNMNT 8
            +VNM+MN+
Sbjct: 1429 NVNMDMNS 1436
>XP_006721101
          Length = 1907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SVNMNMNT 8
            +VNM+MN+
Sbjct: 1465 NVNMDMNS 1472
>XP_005255311
          Length = 1913

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SVNMNMNT 8
            +VNM+MN+
Sbjct: 1471 NVNMDMNS 1478
>XP_005255310
          Length = 1919

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SVNMNMNT 8
            +VNM+MN+
Sbjct: 1477 NVNMDMNS 1484
>NP_005566
          Length = 1025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   VNMNMN 7
           VN+NMN
Sbjct: 692 VNINMN 697
>NP_787116
          Length = 1011

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   VNMNMN 7
           VN+NMN
Sbjct: 678 VNINMN 683
>NP_001240628
          Length = 1419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   VNMNMN 7
           +NMN+N
Sbjct: 763 INMNLN 768
>NP_001092882
          Length = 2004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    NMNMNT 8
            +MNMNT
Sbjct: 1913 SMNMNT 1918
>NP_006757
          Length = 2004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    NMNMNT 8
            +MNMNT
Sbjct: 1913 SMNMNT 1918
>NP_001092883
          Length = 2004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    NMNMNT 8
            +MNMNT
Sbjct: 1913 SMNMNT 1918
>NP_775821
          Length = 1326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 MNMNTS 9
         MN+NTS
Sbjct: 1 MNLNTS 6
>NP_002130
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNMNMNTS 9
           S+N NM++S
Sbjct: 135 SMNFNMSSS 143
>NP_001156008
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNMNMNTS 9
           S+N NM++S
Sbjct: 135 SMNFNMSSS 143
>NP_001155907
          Length = 251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   SVNMNMN 7
           S+N NMN
Sbjct: 225 SLNQNMN 231
>NP_062556
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNMNMNTS 9
           S+N NM++S
Sbjct: 135 SMNFNMSSS 143
>NP_001240630
          Length = 1367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   VNMNMN 7
           +NMN+N
Sbjct: 759 INMNLN 764
>NP_001006600
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   VNMNMN 7
           +NMN+N
Sbjct: 763 INMNLN 768
>NP_061165
          Length = 1371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   VNMNMN 7
           +NMN+N
Sbjct: 763 INMNLN 768
>NP_001240627
          Length = 1346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   VNMNMN 7
           +NMN+N
Sbjct: 763 INMNLN 768
>NP_001240626
          Length = 1412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   VNMNMN 7
           +NMN+N
Sbjct: 763 INMNLN 768
>XP_006717495
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NMNMNTS 9
           NMN NT+
Sbjct: 773 NMNRNTT 779
>XP_006717494
          Length = 1571

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NMNMNTS 9
           NMN NT+
Sbjct: 272 NMNRNTT 278
>XP_006717493
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NMNMNTS 9
           NMN NT+
Sbjct: 311 NMNRNTT 317
>XP_006717492
          Length = 1635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NMNMNTS 9
           NMN NT+
Sbjct: 773 NMNRNTT 779
>XP_006717490
          Length = 1791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NMNMNTS 9
           NMN NT+
Sbjct: 492 NMNRNTT 498
>XP_006717489
          Length = 1945

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NMNMNTS 9
           NMN NT+
Sbjct: 773 NMNRNTT 779
>XP_006717488
          Length = 2031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NMNMNTS 9
           NMN NT+
Sbjct: 773 NMNRNTT 779
>XP_006717487
          Length = 2071

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NMNMNTS 9
           NMN NT+
Sbjct: 773 NMNRNTT 779
>XP_006717486
          Length = 2072

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NMNMNTS 9
           NMN NT+
Sbjct: 773 NMNRNTT 779
>XP_005251455
          Length = 1334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 MNMNTS 9
         MN+NTS
Sbjct: 1 MNLNTS 6
>XP_005251456
          Length = 1334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 MNMNTS 9
         MN+NTS
Sbjct: 1 MNLNTS 6
>XP_005251454
          Length = 1334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 MNMNTS 9
         MN+NTS
Sbjct: 1 MNLNTS 6
>XP_005273706
          Length = 1997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    NMNMNT 8
            +MNMNT
Sbjct: 1906 SMNMNT 1911
>XP_006714723
          Length = 1246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   VNMNMN 7
           +NMN+N
Sbjct: 763 INMNLN 768
>XP_005248613
          Length = 1391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   VNMNMN 7
           +NMN+N
Sbjct: 763 INMNLN 768
>XP_005248612
          Length = 1456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   VNMNMN 7
           +NMN+N
Sbjct: 759 INMNLN 764
>XP_005248611
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   VNMNMN 7
           +NMN+N
Sbjct: 763 INMNLN 768
>NP_001009894
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   VNMNMN 7
           +NMN+N
Sbjct: 287 INMNLN 292
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295   0.0986    0.237 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 397,023
Number of extensions: 663
Number of successful extensions: 75
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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