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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004110                                                              18    1482
NP_055832                                                              16    5631
NP_963920                                                              16    5631
NP_963918                                                              16    5631
XP_005270706                                                           16    5631
XP_005270705                                                           16    5631
NP_057687                                                              15    9605
NP_001275750                                                           15    9605
NP_001095271                                                           15    9605
NP_001095270                                                           15    9605
NP_003866                                                              15    9605
NP_001275752                                                           15    9605
NP_477518                                                              15    9605
XP_006714712                                                           15    9605
XP_005272064                                                           15    9605
XP_006714711                                                           15    9605
XP_006714710                                                           15    9605
XP_005270491                                                           15    9605

>NP_004110
          Length = 993

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVLKMMTQL 9
           S LKMMTQL
Sbjct: 660 SELKMMTQL 668



>NP_055832
          Length = 942

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVLKMMTQL 9
           S LK+MT+L
Sbjct: 231 SYLKLMTEL 239



>NP_963920
          Length = 828

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVLKMMTQL 9
           S LK+MT+L
Sbjct: 231 SYLKLMTEL 239



>NP_963918
          Length = 911

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVLKMMTQL 9
           S LK+MT+L
Sbjct: 200 SYLKLMTEL 208



>XP_005270706
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVLKMMTQL 9
           S LK+MT+L
Sbjct: 231 SYLKLMTEL 239



>XP_005270705
          Length = 934

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVLKMMTQL 9
           S LK+MT+L
Sbjct: 231 SYLKLMTEL 239



>NP_057687
          Length = 915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLKMMTQL 9
           VLK MT+L
Sbjct: 606 VLKWMTEL 613



>NP_001275750
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLKMMTQL 9
           VLKM TQ+
Sbjct: 114 VLKMETQM 121



>NP_001095271
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLKMMTQL 9
           VLK MT+L
Sbjct: 510 VLKWMTEL 517



>NP_001095270
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLKMMTQL 9
           VLK MT+L
Sbjct: 606 VLKWMTEL 613



>NP_003866
          Length = 693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VLKMMTQL 9
           VLKM+T++
Sbjct: 662 VLKMVTEI 669



>NP_001275752
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  VLKMMTQL 9
          VLKM TQ+
Sbjct: 19 VLKMETQM 26



>NP_477518
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLKMMTQL 9
           VLKM TQ+
Sbjct: 94  VLKMETQM 101



>XP_006714712
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLKMMTQL 9
           VLK MT+L
Sbjct: 510 VLKWMTEL 517



>XP_005272064
          Length = 909

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLKMMTQL 9
           VLK MT+L
Sbjct: 628 VLKWMTEL 635



>XP_006714711
          Length = 937

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLKMMTQL 9
           VLK MT+L
Sbjct: 628 VLKWMTEL 635



>XP_006714710
          Length = 937

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLKMMTQL 9
           VLK MT+L
Sbjct: 628 VLKWMTEL 635



>XP_005270491
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  VLKMMTQL 9
          VLKM TQ+
Sbjct: 19 VLKMETQM 26



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.126    0.289 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 243,091
Number of extensions: 273
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)