Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     665
XP_005262424                                                           19     665
NP_036292                                                              17    3301
NP_001265645                                                           17    3301
XP_005266987                                                           17    3301
XP_006715521                                                           17    3301
NP_001273331                                                           16    5631
NP_000237                                                              16    5631
XP_006720946                                                           16    5631
XP_005255380                                                           16    5631
XP_006720945                                                           16    5631
XP_006720944                                                           16    5631
XP_005255378                                                           16    5631
XP_005255377                                                           16    5631
XP_006720943                                                           16    5631
NP_002438                                                              15    9605
NP_001231866                                                           15    9605
NP_001258978                                                           15    9605
NP_057376                                                              15    9605
NP_004332                                                              15    9605
NP_005087                                                              15    9605
NP_001164634                                                           15    9605
NP_001164633                                                           15    9605
NP_963893                                                              15    9605
NP_775862                                                              15    9605
XP_005262367                                                           15    9605
XP_006724778                                                           15    9605
XP_005262366                                                           15    9605
XP_005268859                                                           15    9605
XP_006717649                                                           15    9605
XP_006717648                                                           15    9605
XP_006717645                                                           15    9605
XP_006717642                                                           15    9605
XP_006717640                                                           15    9605
XP_006717639                                                           15    9605
XP_006717638                                                           15    9605
XP_006717637                                                           15    9605
XP_006717636                                                           15    9605
XP_006717635                                                           15    9605
XP_006717634                                                           15    9605
XP_006717633                                                           15    9605
XP_006717632                                                           15    9605
XP_006717631                                                           15    9605
XP_005269471                                                           15    9605
XP_006717630                                                           15    9605
XP_006717629                                                           15    9605
XP_005269469                                                           15    9605
XP_005269468                                                           15    9605
XP_006717628                                                           15    9605
XP_006717627                                                           15    9605
XP_006717626                                                           15    9605
XP_006717625                                                           15    9605
XP_006717624                                                           15    9605
XP_005269463                                                           15    9605
XP_005269461                                                           15    9605
XP_006717623                                                           15    9605
XP_005269462                                                           15    9605
XP_005265227                                                           15    9605
XP_005264615                                                           15    9605
XP_006712164                                                           15    9605
XP_005264614                                                           15    9605
XP_005264613                                                           15    9605
XP_005264612                                                           15    9605
>NP_722576
          Length = 3080

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VLGTRMTS 9
            VLGTRMTS
Sbjct: 1865 VLGTRMTS 1872
>XP_005262424
          Length = 2875

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VLGTRMTS 9
            VLGTRMTS
Sbjct: 1660 VLGTRMTS 1667
>NP_036292
          Length = 621

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           +LGTRM S
Sbjct: 566 ILGTRMVS 573
>NP_001265645
          Length = 621

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           +LGTRM S
Sbjct: 566 ILGTRMVS 573
>XP_005266987
          Length = 597

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           +LGTRM S
Sbjct: 542 ILGTRMVS 549
>XP_006715521
          Length = 621

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           +LGTRM S
Sbjct: 566 ILGTRMVS 573
>NP_001273331
          Length = 1131

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S LGTR+T
Sbjct: 835 SFLGTRLT 842
>NP_000237
          Length = 1130

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S LGTR+T
Sbjct: 834 SFLGTRLT 841
>XP_006720946
          Length = 1081

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S LGTR+T
Sbjct: 785 SFLGTRLT 792
>XP_005255380
          Length = 1082

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S LGTR+T
Sbjct: 786 SFLGTRLT 793
>XP_006720945
          Length = 1096

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S LGTR+T
Sbjct: 800 SFLGTRLT 807
>XP_006720944
          Length = 1097

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S LGTR+T
Sbjct: 801 SFLGTRLT 808
>XP_005255378
          Length = 1145

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S LGTR+T
Sbjct: 849 SFLGTRLT 856
>XP_005255377
          Length = 1146

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S LGTR+T
Sbjct: 850 SFLGTRLT 857
>XP_006720943
          Length = 1208

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S LGTR+T
Sbjct: 912 SFLGTRLT 919
>NP_002438
          Length = 1400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S LGTR+T
Sbjct: 180 SPLGTRVT 187
>NP_001231866
          Length = 1351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S LGTR+T
Sbjct: 180 SPLGTRVT 187
>NP_001258978
          Length = 651

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SVLGTRMTS 9
           +VLG+R+T+
Sbjct: 535 NVLGSRVTN 543
>NP_057376
          Length = 704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SVLGTRMTS 9
           +VLG+R+T+
Sbjct: 588 NVLGSRVTN 596
>NP_004332
          Length = 2225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    VLGTRMTS 9
            VLG  MTS
Sbjct: 1277 VLGVEMTS 1284
>NP_005087
          Length = 1370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S +GT+MT
Sbjct: 303 SAVGTKMT 310
>NP_001164634
          Length = 495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S +GT+MT
Sbjct: 303 SAVGTKMT 310
>NP_001164633
          Length = 1358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S +GT+MT
Sbjct: 303 SAVGTKMT 310
>NP_963893
          Length = 1370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S +GT+MT
Sbjct: 303 SAVGTKMT 310
>NP_775862
          Length = 2344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    VLGTRMTS 9
            VLG  MTS
Sbjct: 1220 VLGANMTS 1227
>XP_005262367
          Length = 1358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S +GT+MT
Sbjct: 303 SAVGTKMT 310
>XP_006724778
          Length = 1370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S +GT+MT
Sbjct: 303 SAVGTKMT 310
>XP_005262366
          Length = 1370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S +GT+MT
Sbjct: 303 SAVGTKMT 310
>XP_005268859
          Length = 2361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    VLGTRMTS 9
            VLG  MTS
Sbjct: 1237 VLGANMTS 1244
>XP_006717649
          Length = 1213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717648
          Length = 1217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717645
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717642
          Length = 1337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717640
          Length = 1424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 318 VLGPRVTS 325
>XP_006717639
          Length = 1472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717638
          Length = 1511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717637
          Length = 1531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717636
          Length = 1539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717635
          Length = 1539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717634
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717633
          Length = 1551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717632
          Length = 1551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 315 VLGPRVTS 322
>XP_006717631
          Length = 1554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 318 VLGPRVTS 325
>XP_005269471
          Length = 1554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 318 VLGPRVTS 325
>XP_006717630
          Length = 1561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717629
          Length = 1563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 327 VLGPRVTS 334
>XP_005269469
          Length = 1563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 327 VLGPRVTS 334
>XP_005269468
          Length = 1563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 327 VLGPRVTS 334
>XP_006717628
          Length = 1570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717627
          Length = 1573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717626
          Length = 1574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717625
          Length = 1575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717624
          Length = 1585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_005269463
          Length = 1586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 350 VLGPRVTS 357
>XP_005269461
          Length = 1595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_006717623
          Length = 1595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_005269462
          Length = 1595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLGTRMTS 9
           VLG R+TS
Sbjct: 359 VLGPRVTS 366
>XP_005265227
          Length = 1401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SVLGTRMT 8
           S LGTR+T
Sbjct: 180 SPLGTRVT 187
>XP_005264615
          Length = 2162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    VLGTRMTS 9
            VLG  MTS
Sbjct: 1214 VLGVEMTS 1221
>XP_006712164
          Length = 2179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    VLGTRMTS 9
            VLG  MTS
Sbjct: 1214 VLGVEMTS 1221
>XP_005264614
          Length = 2191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    VLGTRMTS 9
            VLG  MTS
Sbjct: 1277 VLGVEMTS 1284
>XP_005264613
          Length = 2208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    VLGTRMTS 9
            VLG  MTS
Sbjct: 1277 VLGVEMTS 1284
>XP_005264612
          Length = 2242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    VLGTRMTS 9
            VLG  MTS
Sbjct: 1277 VLGVEMTS 1284
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.118    0.292 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 375,664
Number of extensions: 464
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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