Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           18    1135
NP_036462                                                              18    1135
NP_001243397                                                           18    1135
XP_005269721                                                           18    1135
XP_006718995                                                           17    4312
XP_005274425                                                           17    4312
XP_006718994                                                           17    4312
XP_006718993                                                           17    4312
XP_005274424                                                           17    4312
XP_005274423                                                           17    4312
NP_203753                                                              17    4312
NP_001128661                                                           16    5631
XP_006712544                                                           16    5631
XP_006712543                                                           16    5631
XP_005246573                                                           16    5631
XP_006712542                                                           16    5631
XP_006712541                                                           16    5631
NP_001128660                                                           16    5631
NP_001128659                                                           16    5631
NP_004495                                                              16    5631
NP_067002                                                              16    7355
NP_057063                                                              16    7355
NP_055772                                                              16    7355
NP_004821                                                              16    7355
NP_001257451                                                           16    7355
NP_001257450                                                           16    7355
NP_003589                                                              16    7355
NP_001243591                                                           16    7355
NP_001243590                                                           16    7355
NP_001243589                                                           16    7355
NP_001243587                                                           16    7355
NP_001243588                                                           16    7355
XP_006723491                                                           16    7355
XP_006723490                                                           16    7355
XP_006723489                                                           16    7355
XP_006723488                                                           16    7355
XP_006723487                                                           16    7355
XP_006723486                                                           16    7355
XP_005250902                                                           16    7355
XP_005250901                                                           16    7355
XP_005250900                                                           16    7355
XP_005250899                                                           16    7355
XP_005250898                                                           16    7355
XP_005250897                                                           16    7355
XP_005250896                                                           16    7355
XP_005250895                                                           16    7355
XP_005267280                                                           16    7355
XP_005245441                                                           16    7355
XP_005245439                                                           16    7355
XP_005245440                                                           16    7355
XP_005245438                                                           16    7355
NP_002373                                                              15    9605
NP_001257997                                                           15    9605
NP_660088                                                              15    9605
NP_660089                                                              15    9605
NP_660087                                                              15    9605
NP_932061                                                              15    9605
NP_001257998                                                           15    9605
NP_001025055                                                           15    9605
NP_005432                                                              15    9605
NP_001257448                                                           15    9605
NP_004681                                                              15    9605
NP_065385                                                              15    9605
XP_006715666                                                           15    9605
XP_006715585                                                           15    9605
XP_005267124                                                           15    9605
XP_005267123                                                           15    9605
XP_006715584                                                           15    9605
XP_005267122                                                           15    9605
XP_006715583                                                           15    9605
XP_005267121                                                           15    9605
XP_005270472                                                           15    9605
>NP_001243398
          Length = 1781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SVISVPSLQ 9
            S ISVPSLQ
Sbjct: 1342 SAISVPSLQ 1350
>NP_036462
          Length = 2073

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SVISVPSLQ 9
            S ISVPSLQ
Sbjct: 1634 SAISVPSLQ 1642
>NP_001243397
          Length = 1890

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SVISVPSLQ 9
            S ISVPSLQ
Sbjct: 1451 SAISVPSLQ 1459
>XP_005269721
          Length = 2073

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SVISVPSLQ 9
            S ISVPSLQ
Sbjct: 1634 SAISVPSLQ 1642
>XP_006718995
          Length = 2382

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SVISVPS
Sbjct: 406 SVISVPS 412
>XP_005274425
          Length = 2566

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SVISVPS
Sbjct: 639 SVISVPS 645
>XP_006718994
          Length = 2567

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SVISVPS
Sbjct: 639 SVISVPS 645
>XP_006718993
          Length = 2602

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SVISVPS
Sbjct: 626 SVISVPS 632
>XP_005274424
          Length = 2614

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SVISVPS
Sbjct: 639 SVISVPS 645
>XP_005274423
          Length = 2615

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SVISVPS
Sbjct: 639 SVISVPS 645
>NP_203753
          Length = 2601

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SVISVPS
Sbjct: 626 SVISVPS 632
>NP_001128661
          Length = 522

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SV+SVPS
Sbjct: 319 SVVSVPS 325
>XP_006712544
          Length = 385

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SV+SVPS
Sbjct: 166 SVVSVPS 172
>XP_006712543
          Length = 578

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SV+SVPS
Sbjct: 359 SVVSVPS 365
>XP_005246573
          Length = 586

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SV+SVPS
Sbjct: 383 SVVSVPS 389
>XP_006712542
          Length = 600

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SV+SVPS
Sbjct: 383 SVVSVPS 389
>XP_006712541
          Length = 602

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SV+SVPS
Sbjct: 383 SVVSVPS 389
>NP_001128660
          Length = 560

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SV+SVPS
Sbjct: 359 SVVSVPS 365
>NP_001128659
          Length = 584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SV+SVPS
Sbjct: 383 SVVSVPS 389
>NP_004495
          Length = 562

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVISVPS 7
           SV+SVPS
Sbjct: 359 SVVSVPS 365
>NP_067002
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VISVPSLQ 9
          +ISVP +Q
Sbjct: 83 IISVPGIQ 90
>NP_057063
          Length = 1365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SVISVPSL 8
            SVIS PSL
Sbjct: 1176 SVISSPSL 1183
>NP_055772
          Length = 1198

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VISVPSLQ 9
           V+S+P+LQ
Sbjct: 470 VVSMPNLQ 477
>NP_004821
          Length = 1368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SVISVPSL 8
            SVIS PSL
Sbjct: 1170 SVISSPSL 1177
>NP_001257451
          Length = 1364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SVISVPSL 8
            SVIS PSL
Sbjct: 1170 SVISSPSL 1177
>NP_001257450
          Length = 1359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SVISVPSL 8
            SVIS PSL
Sbjct: 1170 SVISSPSL 1177
>NP_003589
          Length = 447

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VISVPSLQ 9
           +IS PSLQ
Sbjct: 140 LISAPSLQ 147
>NP_001243591
          Length = 319

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  VISVPSLQ 9
          +IS PSLQ
Sbjct: 9  LISAPSLQ 16
>NP_001243590
          Length = 451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VISVPSLQ 9
           +IS PSLQ
Sbjct: 144 LISAPSLQ 151
>NP_001243589
          Length = 451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VISVPSLQ 9
           +IS PSLQ
Sbjct: 144 LISAPSLQ 151
>NP_001243587
          Length = 450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VISVPSLQ 9
           +IS PSLQ
Sbjct: 140 LISAPSLQ 147
>NP_001243588
          Length = 450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VISVPSLQ 9
           +IS PSLQ
Sbjct: 140 LISAPSLQ 147
>XP_006723491
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VISVPSLQ 9
           +IS PSLQ
Sbjct: 140 LISAPSLQ 147
>XP_006723490
          Length = 438

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VISVPSLQ 9
           +IS PSLQ
Sbjct: 144 LISAPSLQ 151
>XP_006723489
          Length = 447

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VISVPSLQ 9
           +IS PSLQ
Sbjct: 140 LISAPSLQ 147
>XP_006723488
          Length = 451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VISVPSLQ 9
           +IS PSLQ
Sbjct: 144 LISAPSLQ 151
>XP_006723487
          Length = 451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VISVPSLQ 9
           +IS PSLQ
Sbjct: 144 LISAPSLQ 151
>XP_006723486
          Length = 451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VISVPSLQ 9
           +IS PSLQ
Sbjct: 144 LISAPSLQ 151
>XP_005250902
          Length = 808

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  VISVPSLQ 9
          V+S+P+LQ
Sbjct: 62 VVSMPNLQ 69
>XP_005250901
          Length = 900

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VISVPSLQ 9
           V+S+P+LQ
Sbjct: 154 VVSMPNLQ 161
>XP_005250900
          Length = 1048

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VISVPSLQ 9
           V+S+P+LQ
Sbjct: 302 VVSMPNLQ 309
>XP_005250899
          Length = 1218

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VISVPSLQ 9
           V+S+P+LQ
Sbjct: 472 VVSMPNLQ 479
>XP_005250898
          Length = 1226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VISVPSLQ 9
           V+S+P+LQ
Sbjct: 498 VVSMPNLQ 505
>XP_005250897
          Length = 1244

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VISVPSLQ 9
           V+S+P+LQ
Sbjct: 498 VVSMPNLQ 505
>XP_005250896
          Length = 1278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VISVPSLQ 9
           V+S+P+LQ
Sbjct: 550 VVSMPNLQ 557
>XP_005250895
          Length = 1296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VISVPSLQ 9
           V+S+P+LQ
Sbjct: 550 VVSMPNLQ 557
>XP_005267280
          Length = 1374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SVISVPSL 8
            SVIS PSL
Sbjct: 1176 SVISSPSL 1183
>XP_005245441
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VISVPSLQ 9
          +ISVP +Q
Sbjct: 83 IISVPGIQ 90
>XP_005245439
          Length = 509

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VISVPSLQ 9
          +ISVP +Q
Sbjct: 83 IISVPGIQ 90
>XP_005245440
          Length = 509

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VISVPSLQ 9
          +ISVP +Q
Sbjct: 83 IISVPGIQ 90
>XP_005245438
          Length = 509

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VISVPSLQ 9
          +ISVP +Q
Sbjct: 83 IISVPGIQ 90
>NP_002373
          Length = 160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SVPSLQ 9
          SVPSLQ
Sbjct: 49 SVPSLQ 54
>NP_001257997
          Length = 87

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SVPSLQ 9
          SVPSLQ
Sbjct: 40 SVPSLQ 45
>NP_660088
          Length = 103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SVPSLQ 9
          SVPSLQ
Sbjct: 49 SVPSLQ 54
>NP_660089
          Length = 96

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SVPSLQ 9
          SVPSLQ
Sbjct: 49 SVPSLQ 54
>NP_660087
          Length = 151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SVPSLQ 9
          SVPSLQ
Sbjct: 40 SVPSLQ 45
>NP_932061
          Length = 83

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SVPSLQ 9
          SVPSLQ
Sbjct: 49 SVPSLQ 54
>NP_001257998
          Length = 74

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SVPSLQ 9
          SVPSLQ
Sbjct: 40 SVPSLQ 45
>NP_001025055
          Length = 1385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SVPSLQ 9
            SVPSLQ
Sbjct: 1128 SVPSLQ 1133
>NP_005432
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SVISVPSLQ 9
           SVIS PS +
Sbjct: 517 SVISTPSTE 525
>NP_001257448
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ISVPSLQ 9
           ISVP LQ
Sbjct: 424 ISVPGLQ 430
>NP_004681
          Length = 1130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ISVPSLQ 9
           ISVP LQ
Sbjct: 424 ISVPGLQ 430
>NP_065385
          Length = 731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SVPSLQ 9
           SVPSLQ
Sbjct: 261 SVPSLQ 266
>XP_006715666
          Length = 886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ISVPSLQ 9
           ISVP LQ
Sbjct: 424 ISVPGLQ 430
>XP_006715585
          Length = 1385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SVPSLQ 9
            SVPSLQ
Sbjct: 1128 SVPSLQ 1133
>XP_005267124
          Length = 1385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SVPSLQ 9
            SVPSLQ
Sbjct: 1128 SVPSLQ 1133
>XP_005267123
          Length = 1385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SVPSLQ 9
            SVPSLQ
Sbjct: 1128 SVPSLQ 1133
>XP_006715584
          Length = 1385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SVPSLQ 9
            SVPSLQ
Sbjct: 1128 SVPSLQ 1133
>XP_005267122
          Length = 1385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SVPSLQ 9
            SVPSLQ
Sbjct: 1128 SVPSLQ 1133
>XP_006715583
          Length = 1431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SVPSLQ 9
            SVPSLQ
Sbjct: 1174 SVPSLQ 1179
>XP_005267121
          Length = 1444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SVPSLQ 9
            SVPSLQ
Sbjct: 1187 SVPSLQ 1192
>XP_005270472
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SVPSLQ 9
          SVPSLQ
Sbjct: 38 SVPSLQ 43
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.122    0.292 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 694,791
Number of extensions: 945
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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