Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004203                                                              18    1482
NP_001121619                                                           18    1935
NP_000258                                                              18    1935
NP_001035957                                                           18    1935
XP_006721991                                                           18    1935
XP_006721990                                                           18    1935
XP_006721989                                                           18    1935
XP_005258041                                                           18    1935
XP_006721988                                                           18    1935
XP_006721987                                                           18    1935
XP_006721986                                                           18    1935
XP_005258040                                                           18    1935
XP_006721985                                                           18    1935
NP_872577                                                              16    5631
NP_001136239                                                           16    5631
NP_001136238                                                           16    5631
NP_149045                                                              16    5631
NP_000341                                                              16    5631
NP_000186                                                              16    5631
XP_005269816                                                           16    5631
XP_005269815                                                           16    5631
XP_005269813                                                           16    5631
XP_005269814                                                           16    5631
XP_005269812                                                           16    5631
NP_001004731                                                           16    5631
NP_057336                                                              16    7355
NP_001073950                                                           16    7355
XP_005267232                                                           16    7355
XP_005267230                                                           16    7355
XP_005267229                                                           16    7355
XP_005267228                                                           16    7355
XP_005267227                                                           16    7355
XP_005267226                                                           16    7355
XP_006712120                                                           16    7355
XP_005264512                                                           16    7355
XP_005264511                                                           16    7355
XP_006712119                                                           16    7355
XP_005264510                                                           16    7355
XP_006712118                                                           16    7355
XP_005264509                                                           16    7355
XP_005264508                                                           16    7355
XP_006712117                                                           16    7355
XP_005264507                                                           16    7355
XP_005264506                                                           16    7355
NP_056041                                                              15    9605
NP_114072                                                              15    9605
NP_006181                                                              15    9605
NP_001230332                                                           15    9605
XP_006721523                                                           15    9605
XP_006720933                                                           15    9605
XP_005255273                                                           15    9605
XP_005255272                                                           15    9605
XP_005255271                                                           15    9605
XP_005255270                                                           15    9605
XP_005255268                                                           15    9605
XP_005255267                                                           15    9605
XP_006712618                                                           15    9605
XP_006711828                                                           15    9605
XP_006711827                                                           15    9605
XP_006711826                                                           15    9605
NP_001026976                                                           15    9605
NP_001001966                                                           15    9605
>NP_004203
          Length = 658

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VIFLLVHS 9
           VIF+LVHS
Sbjct: 114 VIFVLVHS 121
>NP_001121619
          Length = 593

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVIFLLVHS 9
           SVIFLLV S
Sbjct: 340 SVIFLLVQS 348
>NP_000258
          Length = 2818

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVIFLLVHS 9
           SVIFLLV S
Sbjct: 340 SVIFLLVQS 348
>NP_001035957
          Length = 2839

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVIFLLVHS 9
           SVIFLLV S
Sbjct: 340 SVIFLLVQS 348
>XP_006721991
          Length = 1632

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVIFLLVHS 9
           SVIFLLV S
Sbjct: 340 SVIFLLVQS 348
>XP_006721990
          Length = 2823

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVIFLLVHS 9
           SVIFLLV S
Sbjct: 340 SVIFLLVQS 348
>XP_006721989
          Length = 2823

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVIFLLVHS 9
           SVIFLLV S
Sbjct: 340 SVIFLLVQS 348
>XP_005258041
          Length = 2836

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVIFLLVHS 9
           SVIFLLV S
Sbjct: 340 SVIFLLVQS 348
>XP_006721988
          Length = 2846

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVIFLLVHS 9
           SVIFLLV S
Sbjct: 340 SVIFLLVQS 348
>XP_006721987
          Length = 2849

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVIFLLVHS 9
           SVIFLLV S
Sbjct: 340 SVIFLLVQS 348
>XP_006721986
          Length = 2854

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVIFLLVHS 9
           SVIFLLV S
Sbjct: 327 SVIFLLVQS 335
>XP_005258040
          Length = 2857

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVIFLLVHS 9
           SVIFLLV S
Sbjct: 340 SVIFLLVQS 348
>XP_006721985
          Length = 2867

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVIFLLVHS 9
           SVIFLLV S
Sbjct: 340 SVIFLLVQS 348
>NP_872577
          Length = 324

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   FLLVHS 9
           FLLVHS
Sbjct: 210 FLLVHS 215
>NP_001136239
          Length = 1915

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SVIFLLVH 8
            S++FLL H
Sbjct: 1415 SILFLLYH 1422
>NP_001136238
          Length = 1952

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SVIFLLVH 8
            S++FLL H
Sbjct: 1452 SILFLLYH 1459
>NP_149045
          Length = 1955

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SVIFLLVH 8
            S++FLL H
Sbjct: 1455 SILFLLYH 1462
>NP_000341
          Length = 2273

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SVIFLLVHS 9
           SV++LL++S
Sbjct: 176 SVVYLLINS 184
>NP_000186
          Length = 700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   FLLVHS 9
           FLLVHS
Sbjct: 210 FLLVHS 215
>XP_005269816
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  FLLVHS 9
          FLLVHS
Sbjct: 87 FLLVHS 92
>XP_005269815
          Length = 667

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   FLLVHS 9
           FLLVHS
Sbjct: 210 FLLVHS 215
>XP_005269813
          Length = 700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   FLLVHS 9
           FLLVHS
Sbjct: 210 FLLVHS 215
>XP_005269814
          Length = 700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   FLLVHS 9
           FLLVHS
Sbjct: 210 FLLVHS 215
>XP_005269812
          Length = 700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   FLLVHS 9
           FLLVHS
Sbjct: 210 FLLVHS 215
>NP_001004731
          Length = 362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VIFLLVH 8
           V+FLL+H
Sbjct: 95  VMFLLIH 101
>NP_057336
          Length = 4857

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SVIFLLVHS 9
            +++FLL HS
Sbjct: 3714 ALLFLLCHS 3722
>NP_001073950
          Length = 814

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SVIFLLVHS 9
           S +FL +HS
Sbjct: 253 SALFLFLHS 261
>XP_005267232
          Length = 437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SVIFLLVHS 9
           S +FL +HS
Sbjct: 253 SALFLFLHS 261
>XP_005267230
          Length = 649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SVIFLLVHS 9
          S +FL +HS
Sbjct: 88 SALFLFLHS 96
>XP_005267229
          Length = 721

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SVIFLLVHS 9
           S +FL +HS
Sbjct: 253 SALFLFLHS 261
>XP_005267228
          Length = 813

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SVIFLLVHS 9
           S +FL +HS
Sbjct: 252 SALFLFLHS 260
>XP_005267227
          Length = 814

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SVIFLLVHS 9
           S +FL +HS
Sbjct: 253 SALFLFLHS 261
>XP_005267226
          Length = 814

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SVIFLLVHS 9
           S +FL +HS
Sbjct: 253 SALFLFLHS 261
>XP_006712120
          Length = 4812

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SVIFLLVHS 9
            +++FLL HS
Sbjct: 3669 ALLFLLCHS 3677
>XP_005264512
          Length = 4840

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SVIFLLVHS 9
            +++FLL HS
Sbjct: 3697 ALLFLLCHS 3705
>XP_005264511
          Length = 4847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SVIFLLVHS 9
            +++FLL HS
Sbjct: 3741 ALLFLLCHS 3749
>XP_006712119
          Length = 4851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SVIFLLVHS 9
            +++FLL HS
Sbjct: 3708 ALLFLLCHS 3716
>XP_005264510
          Length = 4861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SVIFLLVHS 9
            +++FLL HS
Sbjct: 3718 ALLFLLCHS 3726
>XP_006712118
          Length = 4864

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SVIFLLVHS 9
            +++FLL HS
Sbjct: 3721 ALLFLLCHS 3729
>XP_005264509
          Length = 4870

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SVIFLLVHS 9
            +++FLL HS
Sbjct: 3727 ALLFLLCHS 3735
>XP_005264508
          Length = 4875

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SVIFLLVHS 9
            +++FLL HS
Sbjct: 3732 ALLFLLCHS 3740
>XP_006712117
          Length = 4878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SVIFLLVHS 9
            +++FLL HS
Sbjct: 3735 ALLFLLCHS 3743
>XP_005264507
          Length = 4880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SVIFLLVHS 9
            +++FLL HS
Sbjct: 3737 ALLFLLCHS 3745
>XP_005264506
          Length = 4884

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SVIFLLVHS 9
            +++FLL HS
Sbjct: 3741 ALLFLLCHS 3749
>NP_056041
          Length = 1053

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   SVIFLLVH 8
           S +FL++H
Sbjct: 318 SQVFLIIH 325
>NP_114072
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SVIFLLVH 8
           +V+FLLV+
Sbjct: 397 TVVFLLVY 404
>NP_006181
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   IFLLVHS 9
           +FLL+H+
Sbjct: 388 LFLLIHN 394
>NP_001230332
          Length = 906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   SVIFLLVH 8
           S +FL++H
Sbjct: 316 SQVFLIIH 323
>XP_006721523
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  SVIFLLV 7
          SV+FLLV
Sbjct: 31 SVLFLLV 37
>XP_006720933
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   SVIFLLVH 8
           S +FL++H
Sbjct: 318 SQVFLIIH 325
>XP_005255273
          Length = 884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   SVIFLLVH 8
           S +FL++H
Sbjct: 318 SQVFLIIH 325
>XP_005255272
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   SVIFLLVH 8
           S +FL++H
Sbjct: 318 SQVFLIIH 325
>XP_005255271
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   SVIFLLVH 8
           S +FL++H
Sbjct: 318 SQVFLIIH 325
>XP_005255270
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   SVIFLLVH 8
           S +FL++H
Sbjct: 316 SQVFLIIH 323
>XP_005255268
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   SVIFLLVH 8
           S +FL++H
Sbjct: 318 SQVFLIIH 325
>XP_005255267
          Length = 1051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   SVIFLLVH 8
           S +FL++H
Sbjct: 316 SQVFLIIH 323
>XP_006712618
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   IFLLVHS 9
           +FLL+H+
Sbjct: 388 LFLLIHN 394
>XP_006711828
          Length = 332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  SVIFLLVH 8
          S++FLL++
Sbjct: 49 SILFLLIY 56
>XP_006711827
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  SVIFLLVH 8
          S++FLL++
Sbjct: 26 SILFLLIY 33
>XP_006711826
          Length = 332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  SVIFLLVH 8
          S++FLL++
Sbjct: 49 SILFLLIY 56
>NP_001026976
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VIFLLVH 8
           +IFL+VH
Sbjct: 493 LIFLVVH 499
>NP_001001966
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  SVIFLLVH 8
          S++FLL++
Sbjct: 26 SILFLLIY 33
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.342    0.149    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 470,405
Number of extensions: 868
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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