Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              18    1935
NP_005913                                                              18    1935
XP_005267046                                                           18    1935
XP_005267045                                                           18    1935
NP_064425                                                              17    4312
NP_001001290                                                           17    4312
XP_006714032                                                           17    4312
XP_006714031                                                           17    4312
NP_808224                                                              16    5631
NP_057241                                                              16    5631
NP_001123230                                                           16    5631
NP_002941                                                              16    5631
NP_001034794                                                           16    5631
XP_006724668                                                           16    5631
XP_006724667                                                           16    5631
XP_006724666                                                           16    5631
XP_006724665                                                           16    5631
XP_006724664                                                           16    5631
XP_006724663                                                           16    5631
XP_006724662                                                           16    5631
NP_071752                                                              16    5631
NP_001073291                                                           16    7355
NP_000417                                                              16    7355
NP_078962                                                              16    7355
NP_085076                                                              16    7355
NP_001005417                                                           16    7355
NP_003771                                                              16    7355
XP_005268630                                                           16    7355
XP_005267039                                                           16    7355
XP_005267038                                                           16    7355
XP_006711080                                                           16    7355
XP_005271361                                                           16    7355
XP_005271268                                                           16    7355
XP_006710966                                                           16    7355
XP_005271267                                                           16    7355
XP_005271266                                                           16    7355
XP_005271265                                                           16    7355
NP_001182068                                                           15    9605
NP_056201                                                              15    9605
NP_690001                                                              15    9605
NP_006659                                                              15    9605
XP_006721237                                                           15    9605
XP_005267331                                                           15    9605
XP_006719578                                                           15    9605
XP_006719577                                                           15    9605
XP_006719576                                                           15    9605
XP_006719575                                                           15    9605
XP_006719574                                                           15    9605
XP_006719573                                                           15    9605
XP_005269086                                                           15    9605
XP_006719572                                                           15    9605
XP_006719571                                                           15    9605
XP_005269085                                                           15    9605
XP_006719570                                                           15    9605
XP_006719569                                                           15    9605
XP_006719568                                                           15    9605
XP_006719567                                                           15    9605
>NP_006715
          Length = 1558

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SVIEISRA 8
           SVIEISRA
Sbjct: 793 SVIEISRA 800
>NP_005913
          Length = 1608

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SVIEISRA 8
           SVIEISRA
Sbjct: 793 SVIEISRA 800
>XP_005267046
          Length = 1554

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SVIEISRA 8
           SVIEISRA
Sbjct: 793 SVIEISRA 800
>XP_005267045
          Length = 1604

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SVIEISRA 8
           SVIEISRA
Sbjct: 793 SVIEISRA 800
>NP_064425
          Length = 540

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVIEISRAP 9
           SV+E+ RAP
Sbjct: 303 SVLELLRAP 311
>NP_001001290
          Length = 511

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVIEISRAP 9
           SV+E+ RAP
Sbjct: 274 SVLELLRAP 282
>XP_006714032
          Length = 423

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVIEISRAP 9
           SV+E+ RAP
Sbjct: 274 SVLELLRAP 282
>XP_006714031
          Length = 563

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVIEISRAP 9
           SV+E+ RAP
Sbjct: 303 SVLELLRAP 311
>NP_808224
          Length = 706

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SVIEISRAP 9
           SV EIS AP
Sbjct: 312 SVSEISEAP 320
>NP_057241
          Length = 706

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SVIEISRAP 9
           SV EIS AP
Sbjct: 312 SVSEISEAP 320
>NP_001123230
          Length = 512

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIEISRAP 9
           V+E+S+AP
Sbjct: 303 VLEVSQAP 310
>NP_002941
          Length = 607

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SVIEISRAP 9
           S  EISRAP
Sbjct: 385 SPYEISRAP 393
>NP_001034794
          Length = 1431

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SVIEISRAP 9
           SV EIS AP
Sbjct: 312 SVSEISEAP 320
>XP_006724668
          Length = 681

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SVIEISRAP 9
           SV EIS AP
Sbjct: 312 SVSEISEAP 320
>XP_006724667
          Length = 1387

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SVIEISRAP 9
           SV EIS AP
Sbjct: 268 SVSEISEAP 276
>XP_006724666
          Length = 1387

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SVIEISRAP 9
           SV EIS AP
Sbjct: 268 SVSEISEAP 276
>XP_006724665
          Length = 1431

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SVIEISRAP 9
           SV EIS AP
Sbjct: 312 SVSEISEAP 320
>XP_006724664
          Length = 1431

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SVIEISRAP 9
           SV EIS AP
Sbjct: 312 SVSEISEAP 320
>XP_006724663
          Length = 1431

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SVIEISRAP 9
           SV EIS AP
Sbjct: 312 SVSEISEAP 320
>XP_006724662
          Length = 1431

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SVIEISRAP 9
           SV EIS AP
Sbjct: 312 SVSEISEAP 320
>NP_071752
          Length = 513

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIEISRAP 9
           V+E+S+AP
Sbjct: 303 VLEVSQAP 310
>NP_001073291
          Length = 3118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    IEISRAP 9
            IEISR P
Sbjct: 2495 IEISRTP 2501
>NP_000417
          Length = 3122

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    IEISRAP 9
            IEISR P
Sbjct: 2499 IEISRTP 2505
>NP_078962
          Length = 887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIEISRAP 9
           ++EI+RAP
Sbjct: 347 LLEINRAP 354
>NP_085076
          Length = 401

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VIEISRAP 9
           V+E+SR P
Sbjct: 375 VLEVSRQP 382
>NP_001005417
          Length = 372

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VIEISRAP 9
           V+E+SR P
Sbjct: 346 VLEVSRQP 353
>NP_003771
          Length = 372

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VIEISRAP 9
           V+E+SR P
Sbjct: 346 VLEVSRQP 353
>XP_005268630
          Length = 373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  IEISRAP 9
          IE+S+AP
Sbjct: 6  IEVSKAP 12
>XP_005267039
          Length = 3206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    IEISRAP 9
            IEISR P
Sbjct: 2583 IEISRTP 2589
>XP_005267038
          Length = 3210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    IEISRAP 9
            IEISR P
Sbjct: 2587 IEISRTP 2593
>XP_006711080
          Length = 372

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VIEISRAP 9
           V+E+SR P
Sbjct: 346 VLEVSRQP 353
>XP_005271361
          Length = 372

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VIEISRAP 9
           V+E+SR P
Sbjct: 346 VLEVSRQP 353
>XP_005271268
          Length = 642

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIEISRAP 9
           ++EI+RAP
Sbjct: 102 LLEINRAP 109
>XP_006710966
          Length = 792

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIEISRAP 9
           ++EI+RAP
Sbjct: 347 LLEINRAP 354
>XP_005271267
          Length = 798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIEISRAP 9
           ++EI+RAP
Sbjct: 258 LLEINRAP 265
>XP_005271266
          Length = 798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIEISRAP 9
           ++EI+RAP
Sbjct: 258 LLEINRAP 265
>XP_005271265
          Length = 860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIEISRAP 9
           ++EI+RAP
Sbjct: 320 LLEINRAP 327
>NP_001182068
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVIEISR 7
           SVIE+SR
Sbjct: 171 SVIELSR 177
>NP_056201
          Length = 789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVIEISR 7
           SVIE+SR
Sbjct: 171 SVIELSR 177
>NP_690001
          Length = 1248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IEISRAP 9
           +EI+RAP
Sbjct: 469 LEIARAP 475
>NP_006659
          Length = 500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVIEISRAP 9
           +V+E+SR P
Sbjct: 314 TVMELSRQP 322
>XP_006721237
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  SVIEISR 7
          SVIE+SR
Sbjct: 29 SVIELSR 35
>XP_005267331
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVIEISRAP 9
           +V+E+SR P
Sbjct: 169 TVMELSRQP 177
>XP_006719578
          Length = 1067

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IEISRAP 9
           +EI+RAP
Sbjct: 469 LEIARAP 475
>XP_006719577
          Length = 1184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IEISRAP 9
           +EI+RAP
Sbjct: 469 LEIARAP 475
>XP_006719576
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IEISRAP 9
           +EI+RAP
Sbjct: 469 LEIARAP 475
>XP_006719575
          Length = 1200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IEISRAP 9
           +EI+RAP
Sbjct: 469 LEIARAP 475
>XP_006719574
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IEISRAP 9
           +EI+RAP
Sbjct: 469 LEIARAP 475
>XP_006719573
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IEISRAP 9
           +EI+RAP
Sbjct: 469 LEIARAP 475
>XP_005269086
          Length = 1256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IEISRAP 9
           +EI+RAP
Sbjct: 469 LEIARAP 475
>XP_006719572
          Length = 1259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IEISRAP 9
           +EI+RAP
Sbjct: 469 LEIARAP 475
>XP_006719571
          Length = 1260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IEISRAP 9
           +EI+RAP
Sbjct: 469 LEIARAP 475
>XP_005269085
          Length = 1260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IEISRAP 9
           +EI+RAP
Sbjct: 469 LEIARAP 475
>XP_006719570
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IEISRAP 9
           +EI+RAP
Sbjct: 469 LEIARAP 475
>XP_006719569
          Length = 1283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IEISRAP 9
           +EI+RAP
Sbjct: 469 LEIARAP 475
>XP_006719568
          Length = 1284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IEISRAP 9
           +EI+RAP
Sbjct: 469 LEIARAP 475
>XP_006719567
          Length = 1284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IEISRAP 9
           +EI+RAP
Sbjct: 469 LEIARAP 475
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.127    0.319 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 415,689
Number of extensions: 654
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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