Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1482
NP_671714                                                              18    1482
XP_006715890                                                           18    1482
XP_005250160                                                           18    1482
XP_005250159                                                           18    1482
NP_061136                                                              16    5631
XP_005276776                                                           16    5631
XP_005262564                                                           16    5631
XP_006724827                                                           16    5631
XP_006710324                                                           16    5631
NP_079010                                                              16    7355
XP_006720319                                                           16    7355
>NP_005742
          Length = 3907

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SVAMSTQDQ 9
            S AMSTQDQ
Sbjct: 2268 SDAMSTQDQ 2276
>NP_671714
          Length = 3899

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SVAMSTQDQ 9
            S AMSTQDQ
Sbjct: 2260 SDAMSTQDQ 2268
>XP_006715890
          Length = 3860

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SVAMSTQDQ 9
            S AMSTQDQ
Sbjct: 2221 SDAMSTQDQ 2229
>XP_005250160
          Length = 3939

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SVAMSTQDQ 9
            S AMSTQDQ
Sbjct: 2300 SDAMSTQDQ 2308
>XP_005250159
          Length = 3952

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SVAMSTQDQ 9
            S AMSTQDQ
Sbjct: 2313 SDAMSTQDQ 2321
>NP_061136
          Length = 904

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AMSTQDQ 9
           AMST+DQ
Sbjct: 380 AMSTRDQ 386

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AMSTQDQ 9
           AMST+DQ
Sbjct: 568 AMSTRDQ 574
>XP_005276776
          Length = 991

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AMSTQDQ 9
           AMST+DQ
Sbjct: 862 AMSTRDQ 868
>XP_005262564
          Length = 991

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AMSTQDQ 9
           AMST+DQ
Sbjct: 862 AMSTRDQ 868
>XP_006724827
          Length = 904

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AMSTQDQ 9
           AMST+DQ
Sbjct: 380 AMSTRDQ 386

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AMSTQDQ 9
           AMST+DQ
Sbjct: 568 AMSTRDQ 574
>XP_006710324
          Length = 943

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AMSTQDQ 9
           AMST+DQ
Sbjct: 814 AMSTRDQ 820
>NP_079010
          Length = 1002

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVAMSTQDQ 9
           SVA+S +DQ
Sbjct: 178 SVAISVKDQ 186
>XP_006720319
          Length = 1004

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVAMSTQDQ 9
           SVA+S +DQ
Sbjct: 178 SVAISVKDQ 186
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295   0.0979    0.219 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 298,706
Number of extensions: 248
Number of successful extensions: 14
Number of sequences better than 10000.0: 12
Number of HSP's gapped: 14
Number of HSP's successfully gapped: 14
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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