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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           18    1135
NP_036462                                                              18    1135
NP_001243397                                                           18    1135
XP_005269721                                                           18    1135
XP_005276813                                                           18    1482
XP_005248455                                                           18    1482
NP_001790                                                              18    1482
NP_000982                                                              17    4312
NP_001258652                                                           16    5631
NP_110420                                                              16    5631
XP_006721182                                                           16    5631
XP_006714860                                                           16    5631
XP_006714859                                                           16    5631
XP_005268570                                                           16    5631
NP_073715                                                              15    9605
NP_005669                                                              15    9605

>NP_001243398
          Length = 1781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SVAIKRKR 8
           SVAIKRKR
Sbjct: 826 SVAIKRKR 833



>NP_036462
          Length = 2073

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SVAIKRKR 8
            SVAIKRKR
Sbjct: 1118 SVAIKRKR 1125



>NP_001243397
          Length = 1890

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SVAIKRKR 8
           SVAIKRKR
Sbjct: 935 SVAIKRKR 942



>XP_005269721
          Length = 2073

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SVAIKRKR 8
            SVAIKRKR
Sbjct: 1118 SVAIKRKR 1125



>XP_005276813
          Length = 289

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   SVAIKRKRT 9
           ++AIKRKRT
Sbjct: 267 ALAIKRKRT 275



>XP_005248455
          Length = 289

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   SVAIKRKRT 9
           ++AIKRKRT
Sbjct: 267 ALAIKRKRT 275



>NP_001790
          Length = 346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   SVAIKRKRT 9
           ++AIKRKRT
Sbjct: 324 ALAIKRKRT 332



>NP_000982
          Length = 137

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VAIKRKRT 9
           V +KRKRT
Sbjct: 124 VMVKRKRT 131



>NP_001258652
          Length = 943

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AIKRKRT 9
           A+KRKRT
Sbjct: 649 AMKRKRT 655



>NP_110420
          Length = 1113

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AIKRKRT 9
           A+KRKRT
Sbjct: 819 AMKRKRT 825



>XP_006721182
          Length = 190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  VAIKRKRT 9
          VAI+RKR+
Sbjct: 19 VAIRRKRS 26



>XP_006714860
          Length = 1146

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AIKRKRT 9
           A+KRKRT
Sbjct: 852 AMKRKRT 858



>XP_006714859
          Length = 1188

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AIKRKRT 9
           A+KRKRT
Sbjct: 894 AMKRKRT 900



>XP_005268570
          Length = 1188

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AIKRKRT 9
           A+KRKRT
Sbjct: 894 AMKRKRT 900



>NP_073715
          Length = 71

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VAIKRKRT 9
          V +KR+RT
Sbjct: 23 VQVKRRRT 30



>NP_005669
          Length = 71

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VAIKRKRT 9
          V +KR+RT
Sbjct: 23 VQVKRRRT 30



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.123    0.291 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 425,634
Number of extensions: 311
Number of successful extensions: 16
Number of sequences better than 10000.0: 16
Number of HSP's gapped: 16
Number of HSP's successfully gapped: 16
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)