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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              19     869
XP_005267290                                                           19     869
NP_065145                                                              17    2528
NP_002203                                                              17    3301
NP_001456                                                              17    3301
NP_955367                                                              17    3301
NP_852133                                                              17    3301
NP_852131                                                              17    3301
NP_001230022                                                           17    3301
NP_001254739                                                           17    3301
XP_006714529                                                           17    3301
XP_006714528                                                           17    3301
XP_006714527                                                           17    3301
NP_038203                                                              16    5631
NP_002152                                                              16    5631
XP_006723022                                                           16    5631
XP_005258451                                                           16    5631
NP_001186512                                                           16    7355
NP_065855                                                              16    7355
NP_055792                                                              16    7355
NP_001158287                                                           16    7355
NP_001158286                                                           16    7355
NP_001158288                                                           16    7355
NP_001158289                                                           16    7355
NP_068834                                                              16    7355
NP_569712                                                              16    7355
NP_085059                                                              16    7355
XP_005267475                                                           16    7355
XP_005267473                                                           16    7355
XP_005267472                                                           16    7355
NP_001129599                                                           15    9605
NP_001137378                                                           15    9605
NP_006691                                                              15    9605
NP_056150                                                              15    9605
XP_006719370                                                           15    9605
XP_006719369                                                           15    9605
XP_006719368                                                           15    9605
XP_005245137                                                           15    9605

>NP_005091
          Length = 1782

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  VAEQDELS 9
          VAEQDELS
Sbjct: 68 VAEQDELS 75



>XP_005267290
          Length = 1782

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  VAEQDELS 9
          VAEQDELS
Sbjct: 68 VAEQDELS 75



>NP_065145
          Length = 199

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AEQDELS 9
           AEQDELS
Sbjct: 183 AEQDELS 189



>NP_002203
          Length = 245

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVAEQDELS 9
           S+ +QDELS
Sbjct: 166 SIEDQDELS 174



>NP_001456
          Length = 829

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VAEQDELS 9
           VAEQD++S
Sbjct: 598 VAEQDDIS 605



>NP_955367
          Length = 783

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VAEQDELS 9
           VAEQD++S
Sbjct: 598 VAEQDDIS 605



>NP_852133
          Length = 245

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVAEQDELS 9
           S+ +QDELS
Sbjct: 166 SIEDQDELS 174



>NP_852131
          Length = 226

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVAEQDELS 9
           S+ +QDELS
Sbjct: 147 SIEDQDELS 155



>NP_001230022
          Length = 839

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VAEQDELS 9
           VAEQD++S
Sbjct: 608 VAEQDDIS 615



>NP_001254739
          Length = 245

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SVAEQDELS 9
           S+ +QDELS
Sbjct: 166 SIEDQDELS 174



>XP_006714529
          Length = 829

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VAEQDELS 9
           VAEQD++S
Sbjct: 598 VAEQDDIS 605



>XP_006714528
          Length = 829

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VAEQDELS 9
           VAEQD++S
Sbjct: 598 VAEQDDIS 605



>XP_006714527
          Length = 829

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VAEQDELS 9
           VAEQD++S
Sbjct: 598 VAEQDDIS 605



>NP_038203
          Length = 1262

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SVAEQDELS 9
           SVAE +ELS
Sbjct: 483 SVAELEELS 491



>NP_002152
          Length = 1262

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SVAEQDELS 9
           SVAE +ELS
Sbjct: 483 SVAELEELS 491



>XP_006723022
          Length = 130

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SVAEQDELS 9
          +V E+DELS
Sbjct: 28 NVLEEDELS 36



>XP_005258451
          Length = 140

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SVAEQDELS 9
          +V E+DELS
Sbjct: 28 NVLEEDELS 36



>NP_001186512
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EQDELS 9
           EQDELS
Sbjct: 400 EQDELS 405



>NP_065855
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EQDELS 9
           EQDELS
Sbjct: 400 EQDELS 405



>NP_055792
          Length = 1341

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    AEQDEL 8
            AEQDEL
Sbjct: 1087 AEQDEL 1092



>NP_001158287
          Length = 1301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    AEQDEL 8
            AEQDEL
Sbjct: 1047 AEQDEL 1052



>NP_001158286
          Length = 1328

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    AEQDEL 8
            AEQDEL
Sbjct: 1074 AEQDEL 1079



>NP_001158288
          Length = 614

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AEQDEL 8
           AEQDEL
Sbjct: 360 AEQDEL 365



>NP_001158289
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AEQDEL 8
           AEQDEL
Sbjct: 329 AEQDEL 334



>NP_068834
          Length = 450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  VAEQDEL 8
          VAEQD+L
Sbjct: 69 VAEQDKL 75



>NP_569712
          Length = 1336

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VAEQDEL 8
            VAEQ+EL
Sbjct: 1051 VAEQEEL 1057



>NP_085059
          Length = 1516

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VAEQDEL 8
            VAEQ+EL
Sbjct: 1231 VAEQEEL 1237



>XP_005267475
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AEQDEL 8
           AEQDEL
Sbjct: 329 AEQDEL 334



>XP_005267473
          Length = 1329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    AEQDEL 8
            AEQDEL
Sbjct: 1075 AEQDEL 1080



>XP_005267472
          Length = 1340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    AEQDEL 8
            AEQDEL
Sbjct: 1086 AEQDEL 1091



>NP_001129599
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SVAEQDE 7
           SVAE DE
Sbjct: 626 SVAENDE 632



>NP_001137378
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SVAEQD 6
           SVAEQD
Sbjct: 256 SVAEQD 261



>NP_006691
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SVAEQD 6
           SVAEQD
Sbjct: 256 SVAEQD 261



>NP_056150
          Length = 2210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SVAEQDEL 8
            SVA+ DEL
Sbjct: 2137 SVAQTDEL 2144



>XP_006719370
          Length = 2076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SVAEQDEL 8
            SVA+ DEL
Sbjct: 2003 SVAQTDEL 2010



>XP_006719369
          Length = 2200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SVAEQDEL 8
            SVA+ DEL
Sbjct: 2127 SVAQTDEL 2134



>XP_006719368
          Length = 2209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SVAEQDEL 8
            SVA+ DEL
Sbjct: 2136 SVAQTDEL 2143



>XP_005245137
          Length = 869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SVAEQDE 7
           SVAE DE
Sbjct: 636 SVAENDE 642



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.284    0.105    0.228 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 547,413
Number of extensions: 550
Number of successful extensions: 38
Number of sequences better than 10000.0: 38
Number of HSP's gapped: 38
Number of HSP's successfully gapped: 38
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.7 bits)
S2: 28 (15.4 bits)