Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_149121                                                              17    2528
NP_001164632                                                           17    2528
NP_001164630                                                           17    2528
NP_001164629                                                           17    2528
NP_001164628                                                           17    2528
NP_001164627                                                           17    2528
XP_005259426                                                           17    2528
XP_005259424                                                           17    2528
XP_005259423                                                           17    2528
XP_005252872                                                           17    3301
XP_006718230                                                           17    3301
NP_001014308                                                           16    5631
NP_001265410                                                           16    5631
NP_001265411                                                           16    5631
NP_001265409                                                           16    5631
NP_060039                                                              16    5631
XP_005266524                                                           16    5631
XP_005266523                                                           16    5631
XP_005266522                                                           16    5631
XP_005266521                                                           16    5631
XP_005266519                                                           16    5631
XP_005266518                                                           16    5631
XP_005266517                                                           16    5631
XP_005266515                                                           16    5631
XP_005266514                                                           16    5631
XP_005266512                                                           16    5631
XP_005266513                                                           16    5631
XP_005266511                                                           16    5631
XP_005266510                                                           16    5631
XP_005266509                                                           16    5631
XP_005266508                                                           16    5631
XP_005266507                                                           16    5631
XP_005266506                                                           16    5631
XP_005266505                                                           16    5631
XP_005266504                                                           16    5631
NP_001186308                                                           16    7355
NP_001186307                                                           16    7355
NP_004184                                                              16    7355
XP_006718114                                                           16    7355
XP_005270318                                                           16    7355
XP_006718113                                                           16    7355
XP_006718112                                                           16    7355
XP_006718111                                                           16    7355
XP_006718110                                                           16    7355
NP_001265616                                                           15    9605
NP_001042                                                              15    9605
NP_006717                                                              15    9605
NP_612353                                                              15    9605
NP_001194003                                                           15    9605
NP_001194001                                                           15    9605
NP_001186211                                                           15    9605
NP_002556                                                              15    9605
NP_001194002                                                           15    9605
XP_005261778                                                           15    9605
XP_006724374                                                           15    9605
XP_005258568                                                           15    9605
XP_005263434                                                           15    9605
XP_005263433                                                           15    9605
XP_005263432                                                           15    9605
XP_005263431                                                           15    9605
XP_006714492                                                           15    9605
XP_005263430                                                           15    9605
XP_005263429                                                           15    9605
NP_001194000                                                           15    9605
NP_789781                                                              15    9605
>NP_149121
          Length = 697

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   STVLNFVNV 9
           ST+L+++NV
Sbjct: 592 STILDYINV 600
>NP_001164632
          Length = 454

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   STVLNFVNV 9
           ST+L+++NV
Sbjct: 349 STILDYINV 357
>NP_001164630
          Length = 544

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   STVLNFVNV 9
           ST+L+++NV
Sbjct: 439 STILDYINV 447
>NP_001164629
          Length = 554

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   STVLNFVNV 9
           ST+L+++NV
Sbjct: 449 STILDYINV 457
>NP_001164628
          Length = 602

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   STVLNFVNV 9
           ST+L+++NV
Sbjct: 497 STILDYINV 505
>NP_001164627
          Length = 639

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   STVLNFVNV 9
           ST+L+++NV
Sbjct: 534 STILDYINV 542
>XP_005259426
          Length = 512

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   STVLNFVNV 9
           ST+L+++NV
Sbjct: 407 STILDYINV 415
>XP_005259424
          Length = 549

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   STVLNFVNV 9
           ST+L+++NV
Sbjct: 444 STILDYINV 452
>XP_005259423
          Length = 607

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   STVLNFVNV 9
           ST+L+++NV
Sbjct: 502 STILDYINV 510
>XP_005252872
          Length = 130

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TVLNFVN 8
          TV+NF+N
Sbjct: 14 TVINFIN 20
>XP_006718230
          Length = 202

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TVLNFVN 8
          TV+NF+N
Sbjct: 14 TVINFIN 20
>NP_001014308
          Length = 779

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 541 SAGLNFINV 549
>NP_001265410
          Length = 733

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 542 SAGLNFINV 550
>NP_001265411
          Length = 733

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 542 SAGLNFINV 550
>NP_001265409
          Length = 811

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 620 SAGLNFINV 628
>NP_060039
          Length = 733

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 542 SAGLNFINV 550
>XP_005266524
          Length = 721

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 542 SAGLNFINV 550
>XP_005266523
          Length = 732

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 541 SAGLNFINV 549
>XP_005266522
          Length = 732

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 541 SAGLNFINV 549
>XP_005266521
          Length = 768

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 542 SAGLNFINV 550
>XP_005266519
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 542 SAGLNFINV 550
>XP_005266518
          Length = 800

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 621 SAGLNFINV 629
>XP_005266517
          Length = 812

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 621 SAGLNFINV 629
>XP_005266515
          Length = 846

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 608 SAGLNFINV 616
>XP_005266514
          Length = 846

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 608 SAGLNFINV 616
>XP_005266512
          Length = 847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 621 SAGLNFINV 629
>XP_005266513
          Length = 847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 609 SAGLNFINV 617
>XP_005266511
          Length = 847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 609 SAGLNFINV 617
>XP_005266510
          Length = 858

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 620 SAGLNFINV 628
>XP_005266509
          Length = 858

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 620 SAGLNFINV 628
>XP_005266508
          Length = 858

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 620 SAGLNFINV 628
>XP_005266507
          Length = 859

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 621 SAGLNFINV 629
>XP_005266506
          Length = 859

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 621 SAGLNFINV 629
>XP_005266505
          Length = 859

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 621 SAGLNFINV 629
>XP_005266504
          Length = 859

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           S  LNF+NV
Sbjct: 621 SAGLNFINV 629
>NP_001186308
          Length = 1855

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    STVLNFVN 8
            STVL+FV+
Sbjct: 1074 STVLSFVS 1081
>NP_001186307
          Length = 1856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    STVLNFVN 8
            STVL+FV+
Sbjct: 1075 STVLSFVS 1082
>NP_004184
          Length = 1859

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    STVLNFVN 8
            STVL+FV+
Sbjct: 1074 STVLSFVS 1081
>XP_006718114
          Length = 1850

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    STVLNFVN 8
            STVL+FV+
Sbjct: 1108 STVLSFVS 1115
>XP_005270318
          Length = 1860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    STVLNFVN 8
            STVL+FV+
Sbjct: 1075 STVLSFVS 1082
>XP_006718113
          Length = 1881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    STVLNFVN 8
            STVL+FV+
Sbjct: 1096 STVLSFVS 1103
>XP_006718112
          Length = 1889

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    STVLNFVN 8
            STVL+FV+
Sbjct: 1108 STVLSFVS 1115
>XP_006718111
          Length = 1892

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    STVLNFVN 8
            STVL+FV+
Sbjct: 1107 STVLSFVS 1114
>XP_006718110
          Length = 1893

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    STVLNFVN 8
            STVL+FV+
Sbjct: 1108 STVLSFVS 1115
>NP_001265616
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VLNFVNV 9
           VLN VNV
Sbjct: 275 VLNIVNV 281
>NP_001042
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VLNFVNV 9
           VLN VNV
Sbjct: 275 VLNIVNV 281
>NP_006717
          Length = 2863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TVLNFVN 8
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>NP_612353
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VLNFVNV 9
          +LNFVN+
Sbjct: 72 LLNFVNL 78
>NP_001194003
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VLNFVNV 9
          +LNFVN+
Sbjct: 10 LLNFVNL 16
>NP_001194001
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VLNFVNV 9
          +LNFVN+
Sbjct: 10 LLNFVNL 16
>NP_001186211
          Length = 2851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TVLNFVN 8
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>NP_002556
          Length = 365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VLNFVNV 9
           VLN VNV
Sbjct: 280 VLNIVNV 286
>NP_001194002
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VLNFVNV 9
          +LNFVN+
Sbjct: 10 LLNFVNL 16
>XP_005261778
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VLNFVNV 9
           VLN VNV
Sbjct: 275 VLNIVNV 281
>XP_006724374
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VLNFVNV 9
           VLN VNV
Sbjct: 275 VLNIVNV 281
>XP_005258568
          Length = 1029

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           +  LNF+NV
Sbjct: 661 TVTLNFMNV 669
>XP_005263434
          Length = 1557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TVLNFVN 8
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>XP_005263433
          Length = 2832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TVLNFVN 8
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>XP_005263432
          Length = 2852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TVLNFVN 8
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>XP_005263431
          Length = 2857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TVLNFVN 8
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>XP_006714492
          Length = 2867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TVLNFVN 8
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>XP_005263430
          Length = 2868

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TVLNFVN 8
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>XP_005263429
          Length = 2868

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TVLNFVN 8
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>NP_001194000
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VLNFVNV 9
          +LNFVN+
Sbjct: 10 LLNFVNL 16
>NP_789781
          Length = 1048

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   STVLNFVNV 9
           +  LNF+NV
Sbjct: 661 TVTLNFMNV 669
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.133    0.345 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 320,068
Number of extensions: 409
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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