Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              19     869
NP_001120972                                                           19     869
XP_006716054                                                           19     869
XP_006716053                                                           19     869
XP_006716052                                                           19     869
XP_006716051                                                           19     869
NP_001274152                                                           17    2528
NP_054858                                                              17    2528
NP_071351                                                              16    7355
NP_079355                                                              15    9605
NP_000120                                                              15    9605
NP_036516                                                              15    9605
NP_001139433                                                           15    9605
NP_005063                                                              15    9605
NP_001139436                                                           15    9605
NP_001139435                                                           15    9605
NP_001139434                                                           15    9605
NP_976224                                                              15    9605
NP_071903                                                              15    9605
NP_001136336                                                           15    9605
NP_872393                                                              15    9605
XP_006724219                                                           15    9605
XP_006724218                                                           15    9605
XP_006724217                                                           15    9605
XP_006723839                                                           15    9605
XP_005260259                                                           15    9605
XP_006721417                                                           15    9605
XP_006721416                                                           15    9605
XP_005254432                                                           15    9605
XP_006720566                                                           15    9605
XP_005249616                                                           15    9605
XP_005249615                                                           15    9605
XP_005249613                                                           15    9605
XP_005249612                                                           15    9605
XP_006715073                                                           15    9605
XP_006712515                                                           15    9605
XP_006712514                                                           15    9605
XP_006712513                                                           15    9605
XP_006712512                                                           15    9605
XP_006712511                                                           15    9605
XP_006712510                                                           15    9605
XP_006712509                                                           15    9605
XP_005246533                                                           15    9605
XP_006712508                                                           15    9605
XP_006710989                                                           15    9605
XP_005271283                                                           15    9605
NP_115893                                                              15    9605
NP_689726                                                              15    9605
>NP_000236
          Length = 1390

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   STVLGKLIV 9
           STVLGK+IV
Sbjct: 917 STVLGKVIV 925
>NP_001120972
          Length = 1408

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   STVLGKLIV 9
           STVLGK+IV
Sbjct: 935 STVLGKVIV 943
>XP_006716054
          Length = 960

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   STVLGKLIV 9
           STVLGK+IV
Sbjct: 487 STVLGKVIV 495
>XP_006716053
          Length = 960

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   STVLGKLIV 9
           STVLGK+IV
Sbjct: 487 STVLGKVIV 495
>XP_006716052
          Length = 1409

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   STVLGKLIV 9
           STVLGK+IV
Sbjct: 936 STVLGKVIV 944
>XP_006716051
          Length = 1427

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   STVLGKLIV 9
           STVLGK+IV
Sbjct: 954 STVLGKVIV 962
>NP_001274152
          Length = 1791

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TVLGKLIV 9
           TV+GKL+V
Sbjct: 795 TVIGKLVV 802
>NP_054858
          Length = 1791

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TVLGKLIV 9
           TV+GKL+V
Sbjct: 795 TVIGKLVV 802
>NP_071351
          Length = 2752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    TVLGKLI 8
            TVLGK+I
Sbjct: 2255 TVLGKVI 2261
>NP_079355
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  STVLGKLI 8
          +TVLG+L+
Sbjct: 79 NTVLGELV 86
>NP_000120
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STVLGKLIV 9
           +T +GKLIV
Sbjct: 458 ATHIGKLIV 466
>NP_036516
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   STVLGK 6
           STVLGK
Sbjct: 407 STVLGK 412
>NP_001139433
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  STVLGKLI 8
          S++LGKL+
Sbjct: 80 SSLLGKLV 87
>NP_005063
          Length = 1085

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  STVLGKLI 8
          S++LGKL+
Sbjct: 80 SSLLGKLV 87
>NP_001139436
          Length = 1054

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  STVLGKLI 8
          S++LGKL+
Sbjct: 49 SSLLGKLV 56
>NP_001139435
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  STVLGKLI 8
          S++LGKL+
Sbjct: 74 SSLLGKLV 81
>NP_001139434
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  STVLGKLI 8
          S++LGKL+
Sbjct: 82 SSLLGKLV 89
>NP_976224
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   STVLGK 6
           STVLGK
Sbjct: 247 STVLGK 252
>NP_071903
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TVLGKLIV 9
           TV+G+L+V
Sbjct: 218 TVMGQLLV 225
>NP_001136336
          Length = 2521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    TVLGKL 7
            TVLGKL
Sbjct: 2026 TVLGKL 2031
>NP_872393
          Length = 3234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   STVLGKL 7
           +T+LGKL
Sbjct: 514 TTILGKL 520
>XP_006724219
          Length = 1157

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TVLGKLI 8
           T+LGKL+
Sbjct: 156 TLLGKLV 162
>XP_006724218
          Length = 1200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TVLGKLI 8
           T+LGKL+
Sbjct: 156 TLLGKLV 162
>XP_006724217
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TVLGKLI 8
           T+LGKL+
Sbjct: 156 TLLGKLV 162
>XP_006723839
          Length = 452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   STVLGK 6
           STVLGK
Sbjct: 329 STVLGK 334
>XP_005260259
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   STVLGK 6
           STVLGK
Sbjct: 407 STVLGK 412
>XP_006721417
          Length = 2497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    TVLGKL 7
            TVLGKL
Sbjct: 2002 TVLGKL 2007
>XP_006721416
          Length = 2504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    TVLGKL 7
            TVLGKL
Sbjct: 2009 TVLGKL 2014
>XP_005254432
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  STVLGK 6
          STVLGK
Sbjct: 64 STVLGK 69
>XP_006720566
          Length = 585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   STVLGK 6
           STVLGK
Sbjct: 247 STVLGK 252
>XP_005249616
          Length = 284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  TVLGKLIV 9
          TV+G+L+V
Sbjct: 66 TVMGQLLV 73
>XP_005249615
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TVLGKLIV 9
           TV+G+L+V
Sbjct: 218 TVMGQLLV 225
>XP_005249613
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  TVLGKLIV 9
          TV+G+L+V
Sbjct: 66 TVMGQLLV 73
>XP_005249612
          Length = 436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TVLGKLIV 9
           TV+G+L+V
Sbjct: 218 TVMGQLLV 225
>XP_006715073
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STVLGKLIV 9
           +T +GKLIV
Sbjct: 458 ATHIGKLIV 466
>XP_006712515
          Length = 3232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   STVLGKL 7
           +T+LGKL
Sbjct: 514 TTILGKL 520
>XP_006712514
          Length = 2496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   STVLGKL 7
           +T+LGKL
Sbjct: 514 TTILGKL 520
>XP_006712513
          Length = 3220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   STVLGKL 7
           +T+LGKL
Sbjct: 514 TTILGKL 520
>XP_006712512
          Length = 3237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   STVLGKL 7
           +T+LGKL
Sbjct: 514 TTILGKL 520
>XP_006712511
          Length = 3256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   STVLGKL 7
           +T+LGKL
Sbjct: 514 TTILGKL 520
>XP_006712510
          Length = 3305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   STVLGKL 7
           +T+LGKL
Sbjct: 514 TTILGKL 520
>XP_006712509
          Length = 3319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   STVLGKL 7
           +T+LGKL
Sbjct: 514 TTILGKL 520
>XP_005246533
          Length = 3323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   STVLGKL 7
           +T+LGKL
Sbjct: 514 TTILGKL 520
>XP_006712508
          Length = 3324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   STVLGKL 7
           +T+LGKL
Sbjct: 514 TTILGKL 520
>XP_006710989
          Length = 283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  STVLGKLI 8
          +TVLG+L+
Sbjct: 79 NTVLGELV 86
>XP_005271283
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  STVLGKLI 8
          +TVLG+L+
Sbjct: 79 NTVLGELV 86
>NP_115893
          Length = 3258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   STVLGKL 7
           +T+LGKL
Sbjct: 514 TTILGKL 520
>NP_689726
          Length = 1274

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TVLGKLI 8
           T+LGKL+
Sbjct: 156 TLLGKLV 162
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.143    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 405,154
Number of extensions: 580
Number of successful extensions: 48
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 48
Number of HSP's successfully gapped: 48
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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