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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055186                                                              17    3301
NP_001278407                                                           17    3301
XP_005259911                                                           17    3301
NP_078966                                                              17    4312
NP_001162593                                                           17    4312
NP_002016                                                              17    4312
NP_001162594                                                           17    4312
NP_001162595                                                           17    4312
NP_001162596                                                           17    4312
NP_001164099                                                           17    4312
NP_055238                                                              17    4312
XP_006723004                                                           17    4312
XP_005272021                                                           17    4312
XP_006714650                                                           17    4312
XP_005272020                                                           17    4312
NP_689412                                                              16    5631
NP_689410                                                              16    5631
NP_006231                                                              16    5631
NP_003698                                                              16    5631
XP_005274610                                                           16    5631
NP_005323                                                              16    7355
XP_005255345                                                           16    7355
XP_005255344                                                           16    7355
NP_001449                                                              15    9605
NP_001120959                                                           15    9605
NP_612430                                                              15    9605
XP_006715973                                                           15    9605

>NP_055186
          Length = 646

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TTKTKRTE 9
           T KTK+TE
Sbjct: 437 TNKTKKTE 444



>NP_001278407
          Length = 585

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TTKTKRTE 9
           T KTK+TE
Sbjct: 376 TNKTKKTE 383



>XP_005259911
          Length = 612

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TTKTKRTE 9
           T KTK+TE
Sbjct: 403 TNKTKKTE 410



>NP_078966
          Length = 14507

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    STTKTKRTE 9
            +TTK  RTE
Sbjct: 8736 ATTKVSRTE 8744



>NP_001162593
          Length = 1276

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STTKTKRTE 9
           ++TK KRTE
Sbjct: 917 TSTKPKRTE 925



>NP_002016
          Length = 1311

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STTKTKRTE 9
           ++TK KRTE
Sbjct: 950 TSTKPKRTE 958



>NP_001162594
          Length = 1301

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STTKTKRTE 9
           ++TK KRTE
Sbjct: 940 TSTKPKRTE 948



>NP_001162595
          Length = 1276

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STTKTKRTE 9
           ++TK KRTE
Sbjct: 915 TSTKPKRTE 923



>NP_001162596
          Length = 1272

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STTKTKRTE 9
           ++TK KRTE
Sbjct: 911 TSTKPKRTE 919



>NP_001164099
          Length = 952

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STTKTKRTE 9
           ++TK KRTE
Sbjct: 591 TSTKPKRTE 599



>NP_055238
          Length = 1163

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STTKTKRTE 9
           ST+K K+TE
Sbjct: 860 STSKQKKTE 868



>XP_006723004
          Length = 6443

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STTKTKRTE 9
           +TTK  RTE
Sbjct: 650 ATTKVSRTE 658



>XP_005272021
          Length = 785

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STTKTKRTE 9
           ST+K K+TE
Sbjct: 482 STSKQKKTE 490



>XP_006714650
          Length = 1134

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STTKTKRTE 9
           ST+K K+TE
Sbjct: 831 STSKQKKTE 839



>XP_005272020
          Length = 1163

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STTKTKRTE 9
           ST+K K+TE
Sbjct: 860 STSKQKKTE 868



>NP_689412
          Length = 591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  STTKTKRTE 9
          S+TKT+R++
Sbjct: 6  SSTKTRRSD 14



>NP_689410
          Length = 625

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  STTKTKRTE 9
          S+TKT+R++
Sbjct: 6  SSTKTRRSD 14



>NP_006231
          Length = 653

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  STTKTKRTE 9
          S+TKT+R++
Sbjct: 6  SSTKTRRSD 14



>NP_003698
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  STTKTKR 7
          STTKT+R
Sbjct: 8  STTKTQR 14



>XP_005274610
          Length = 653

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  STTKTKRTE 9
          S+TKT+R++
Sbjct: 6  SSTKTRRSD 14



>NP_005323
          Length = 142

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1 STTKTKRT 8
         S TKT+RT
Sbjct: 2 SLTKTERT 9



>XP_005255345
          Length = 142

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1 STTKTKRT 8
         S TKT+RT
Sbjct: 2 SLTKTERT 9



>XP_005255344
          Length = 154

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  STTKTKRT 8
          S TKT+RT
Sbjct: 14 SLTKTERT 21



>NP_001449
          Length = 2725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TKTKRTE 9
            T+T+RTE
Sbjct: 2186 TRTERTE 2192



>NP_001120959
          Length = 2692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TKTKRTE 9
            T+T+RTE
Sbjct: 2153 TRTERTE 2159



>NP_612430
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   STTKTKRTE 9
           +T +TKRT+
Sbjct: 377 NTEETKRTD 385



>XP_006715973
          Length = 2632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TKTKRTE 9
            T+T+RTE
Sbjct: 2093 TRTERTE 2099



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.281   0.0928    0.210 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 375,095
Number of extensions: 493
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)