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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     665
XP_005262424                                                           19     665
NP_001005469                                                           17    2528
NP_001004457                                                           17    2528
NP_789743                                                              17    4312
NP_001005243                                                           16    5631
NP_001130010                                                           16    5631
NP_061141                                                              16    5631
XP_005255020                                                           16    5631
NP_079523                                                              16    5631
NP_001034764                                                           16    5631
NP_001005284                                                           16    5631
NP_004940                                                              16    7355
NP_077740                                                              16    7355
NP_758519                                                              16    7355
NP_000751                                                              16    7355
NP_724781                                                              16    7355
XP_005258263                                                           16    7355
XP_006720777                                                           16    7355
XP_005247723                                                           16    7355
XP_005270552                                                           16    7355
XP_005270550                                                           16    7355
XP_005270549                                                           16    7355
NP_001005278                                                           16    7355
NP_542170                                                              15    9605
XP_005260667                                                           15    9605
XP_005260668                                                           15    9605
NP_001035194                                                           15    9605

>NP_722576
          Length = 3080

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STSMSTTLC 9
           STSMSTT C
Sbjct: 409 STSMSTTPC 417



>XP_005262424
          Length = 2875

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STSMSTTLC 9
           STSMSTT C
Sbjct: 204 STSMSTTPC 212



>NP_001005469
          Length = 314

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   STSMSTTLC 9
           +T+M+TT+C
Sbjct: 131 TTTMTTTVC 139



>NP_001004457
          Length = 330

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STSMSTTLC 9
           STSMS  LC
Sbjct: 150 STSMSPQLC 158



>NP_789743
          Length = 342

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STSMSTTLC 9
           S S+STT C
Sbjct: 163 SPSLSTTAC 171



>NP_001005243
          Length = 335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   STSMSTTLC 9
           S  MST LC
Sbjct: 158 SVQMSTRLC 166



>NP_001130010
          Length = 1090

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TSMSTTLC 9
           T+M+T LC
Sbjct: 420 TAMNTVLC 427



>NP_061141
          Length = 944

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TSMSTTLC 9
           TSM  TLC
Sbjct: 846 TSMRPTLC 853



>XP_005255020
          Length = 799

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TSMSTTLC 9
           TSM  TLC
Sbjct: 701 TSMRPTLC 708



>NP_079523
          Length = 1059

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TSMSTTLC 9
           T+M+T LC
Sbjct: 389 TAMNTVLC 396



>NP_001034764
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TSMSTTLC 9
           TSM  TLC
Sbjct: 831 TSMRPTLC 838



>NP_001005284
          Length = 327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STSMSTTLC 9
           S +MST LC
Sbjct: 148 SGTMSTALC 156



>NP_004940
          Length = 847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   TSMSTTLC 9
           TS+  TLC
Sbjct: 662 TSLDVTLC 669



>NP_077740
          Length = 901

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   TSMSTTLC 9
           TS+  TLC
Sbjct: 662 TSLDVTLC 669



>NP_758519
          Length = 783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TSMSTTLC 9
           TSMS  LC
Sbjct: 211 TSMSPQLC 218



>NP_000751
          Length = 836

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TSMSTTLC 9
           TSMS  LC
Sbjct: 211 TSMSPQLC 218



>NP_724781
          Length = 863

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TSMSTTLC 9
           TSMS  LC
Sbjct: 211 TSMSPQLC 218



>XP_005258263
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   TSMSTTLC 9
           TS+  TLC
Sbjct: 519 TSLDVTLC 526



>XP_006720777
          Length = 292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 MSTTLC 9
         M+TTLC
Sbjct: 1 MNTTLC 6



>XP_005247723
          Length = 1481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   STSMSTT 7
           +TSMSTT
Sbjct: 581 NTSMSTT 587



>XP_005270552
          Length = 731

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  TSMSTTLC 9
          TSMS  LC
Sbjct: 79 TSMSPQLC 86



>XP_005270550
          Length = 835

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TSMSTTLC 9
           TSMS  LC
Sbjct: 211 TSMSPQLC 218



>XP_005270549
          Length = 841

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TSMSTTLC 9
           TSMS  LC
Sbjct: 189 TSMSPQLC 196



>NP_001005278
          Length = 317

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MSTTLC 9
           M+TTLC
Sbjct: 136 MTTTLC 141



>NP_542170
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   TSMSTTLC 9
           TS+ +T+C
Sbjct: 196 TSLQSTMC 203



>XP_005260667
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   TSMSTTLC 9
           TS+ +T+C
Sbjct: 196 TSLQSTMC 203



>XP_005260668
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   TSMSTTLC 9
           TS+ +T+C
Sbjct: 196 TSLQSTMC 203



>NP_001035194
          Length = 4493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   STSMSTTL 8
           STS STTL
Sbjct: 121 STSDSTTL 128



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.101    0.277 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 324,213
Number of extensions: 474
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)