Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_006719747                                                           18    1482
XP_005269273                                                           18    1482
NP_000209                                                              16    5631
NP_861463                                                              16    5631
NP_689621                                                              16    5631
NP_001092741                                                           16    5631
XP_005248493                                                           16    5631
XP_005248492                                                           16    5631
NP_001185761                                                           16    7355
NP_004216                                                              16    7355
NP_060821                                                              16    7355
NP_001185763                                                           16    7355
NP_055459                                                              16    7355
NP_848599                                                              16    7355
XP_006726410                                                           16    7355
XP_005269081                                                           16    7355
XP_006713081                                                           16    7355
XP_006711719                                                           16    7355
XP_006711718                                                           16    7355
XP_006711717                                                           16    7355
XP_006711716                                                           16    7355
XP_006711715                                                           16    7355
XP_006711714                                                           16    7355
XP_006711713                                                           16    7355
XP_006711712                                                           16    7355
XP_006711711                                                           16    7355
XP_006711710                                                           16    7355
XP_006711709                                                           16    7355
XP_005277503                                                           16    7355
XP_005273038                                                           16    7355
XP_006711708                                                           16    7355
XP_005277500                                                           16    7355
XP_006711707                                                           16    7355
XP_005277499                                                           16    7355
XP_006711706                                                           16    7355
XP_006711705                                                           16    7355
XP_006711164                                                           16    7355
XP_006710143                                                           16    7355
XP_006710142                                                           16    7355
XP_006710141                                                           16    7355
NP_001229758                                                           15    9605
NP_056538                                                              15    9605
NP_001242938                                                           15    9605
NP_001242937                                                           15    9605
NP_001242936                                                           15    9605
NP_695005                                                              15    9605
NP_001006115                                                           15    9605
XP_005250453                                                           15    9605
NP_114096                                                              15    9605
NP_112223                                                              15    9605
>XP_006719747
          Length = 230

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   STSASRGLR 9
           +TSA+RGLR
Sbjct: 102 ATSAARGLR 110
>XP_005269273
          Length = 309

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   STSASRGLR 9
           +TSA+RGLR
Sbjct: 102 ATSAARGLR 110
>NP_000209
          Length = 676

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSASRGLR 9
           +TSA RG+R
Sbjct: 223 ATSAIRGIR 231
>NP_861463
          Length = 549

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSASRGLR 9
           +TSA RG+R
Sbjct: 96  ATSAIRGIR 104
>NP_689621
          Length = 550

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   STSASRGL 8
           STSASR L
Sbjct: 523 STSASRSL 530
>NP_001092741
          Length = 575

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   STSASRGL 8
           STSASR L
Sbjct: 548 STSASRSL 555
>XP_005248493
          Length = 547

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   STSASRGL 8
           STSASR L
Sbjct: 520 STSASRSL 527
>XP_005248492
          Length = 548

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   STSASRGL 8
           STSASR L
Sbjct: 521 STSASRSL 528
>NP_001185761
          Length = 2240

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1616 STSASQGAK 1624
>NP_004216
          Length = 1052

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STSASRGLR 9
           +  ASRGLR
Sbjct: 464 TADASRGLR 472
>NP_060821
          Length = 1430

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TSASRGLR 9
           TSA+ GLR
Sbjct: 711 TSAANGLR 718
>NP_001185763
          Length = 2362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1660 STSASQGAK 1668
>NP_055459
          Length = 2346

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1660 STSASQGAK 1668
>NP_848599
          Length = 3092

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    STSASRG 7
            STSA+RG
Sbjct: 1057 STSAARG 1063
>XP_006726410
          Length = 2087

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1463 STSASQGAK 1471
>XP_005269081
          Length = 1389

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TSASRGLR 9
           TSA+ GLR
Sbjct: 711 TSAANGLR 718
>XP_006713081
          Length = 3964

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    STSASRG 7
            STSA+RG
Sbjct: 1080 STSAARG 1086
>XP_006711719
          Length = 2302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1616 STSASQGAK 1624
>XP_006711718
          Length = 1436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSASRGLR 9
           STSAS+G +
Sbjct: 667 STSASQGAK 675
>XP_006711717
          Length = 2385

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1616 STSASQGAK 1624
>XP_006711716
          Length = 2411

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1725 STSASQGAK 1733
>XP_006711715
          Length = 2428

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1659 STSASQGAK 1667
>XP_006711714
          Length = 2429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1660 STSASQGAK 1668
>XP_006711713
          Length = 2432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1663 STSASQGAK 1671
>XP_006711712
          Length = 2473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1823 STSASQGAK 1831
>XP_006711711
          Length = 2482

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1713 STSASQGAK 1721
>XP_006711710
          Length = 2494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1725 STSASQGAK 1733
>XP_006711709
          Length = 2495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1726 STSASQGAK 1734
>XP_005277503
          Length = 2498

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1823 STSASQGAK 1831
>XP_005273038
          Length = 2509

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1823 STSASQGAK 1831
>XP_006711708
          Length = 2512

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1823 STSASQGAK 1831
>XP_005277500
          Length = 2525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1823 STSASQGAK 1831
>XP_006711707
          Length = 2553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1823 STSASQGAK 1831
>XP_005277499
          Length = 2561

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1823 STSASQGAK 1831
>XP_006711706
          Length = 2591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1822 STSASQGAK 1830
>XP_006711705
          Length = 2592

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1823 STSASQGAK 1831
>XP_006711164
          Length = 2087

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    STSASRGLR 9
            STSAS+G +
Sbjct: 1463 STSASQGAK 1471
>XP_006710143
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSASRGLR 9
           STSAS+G +
Sbjct: 502 STSASQGAK 510
>XP_006710142
          Length = 671

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSASRGLR 9
           STSAS+G +
Sbjct: 611 STSASQGAK 619
>XP_006710141
          Length = 672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSASRGLR 9
           STSAS+G +
Sbjct: 612 STSASQGAK 620
>NP_001229758
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSASRGLR 9
           STSA+ G+R
Sbjct: 251 STSATLGVR 259
>NP_056538
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  STSASRGL 8
          STSA +GL
Sbjct: 87 STSAPKGL 94
>NP_001242938
          Length = 720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  STSASRGL 8
          STSA +GL
Sbjct: 87 STSAPKGL 94
>NP_001242937
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  STSASRGL 8
          STSA +GL
Sbjct: 87 STSAPKGL 94
>NP_001242936
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  STSASRGL 8
          STSA +GL
Sbjct: 87 STSAPKGL 94
>NP_695005
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSASRGLR 9
           STSA+ G+R
Sbjct: 251 STSATLGVR 259
>NP_001006115
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  STSASRGLR 9
          STSA+ G+R
Sbjct: 86 STSATLGVR 94
>XP_005250453
          Length = 720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  STSASRGL 8
          STSA +GL
Sbjct: 87 STSAPKGL 94
>NP_114096
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  STSASRG 7
          STS SRG
Sbjct: 49 STSTSRG 55
>NP_112223
          Length = 755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ASRGLR 9
           ASRGLR
Sbjct: 630 ASRGLR 635
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.111    0.266 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 329,649
Number of extensions: 307
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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