Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1135
XP_005262424                                                           18    1135
NP_078787                                                              18    1935
NP_001275763                                                           16    5631
XP_006722983                                                           16    5631
NP_001180442                                                           16    7355
NP_001180443                                                           16    7355
NP_060434                                                              16    7355
NP_056197                                                              16    7355
NP_065770                                                              16    7355
NP_001180444                                                           16    7355
XP_006724993                                                           16    7355
XP_006724992                                                           16    7355
XP_006724991                                                           16    7355
XP_006724990                                                           16    7355
XP_006724989                                                           16    7355
XP_006724988                                                           16    7355
XP_006724987                                                           16    7355
XP_006724986                                                           16    7355
XP_006724985                                                           16    7355
XP_006724984                                                           16    7355
XP_006724983                                                           16    7355
XP_006724982                                                           16    7355
XP_006724981                                                           16    7355
XP_006724980                                                           16    7355
XP_006724979                                                           16    7355
XP_006724978                                                           16    7355
XP_006724977                                                           16    7355
XP_006724976                                                           16    7355
XP_006724460                                                           16    7355
XP_006724459                                                           16    7355
XP_005261947                                                           16    7355
XP_006724458                                                           16    7355
XP_005261945                                                           16    7355
XP_006724457                                                           16    7355
XP_006724456                                                           16    7355
XP_006724455                                                           16    7355
XP_005267560                                                           16    7355
XP_005267559                                                           16    7355
XP_006712109                                                           16    7355
NP_061836                                                              15    9605
NP_387505                                                              15    9605
XP_005261051                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    STSALTAYT 9
            STSAL AYT
Sbjct: 1382 STSALPAYT 1390
>XP_005262424
          Length = 2875

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    STSALTAYT 9
            STSAL AYT
Sbjct: 1177 STSALPAYT 1185
>NP_078787
          Length = 603

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           ST+ALT YT
Sbjct: 210 STAALTLYT 218
>NP_001275763
          Length = 625

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TSALTAYT 9
           T ALTAY+
Sbjct: 545 TKALTAYS 552
>XP_006722983
          Length = 625

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TSALTAYT 9
           T ALTAY+
Sbjct: 545 TKALTAYS 552
>NP_001180442
          Length = 501

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  ALTAYT 9
          ALTAYT
Sbjct: 59 ALTAYT 64
>NP_001180443
          Length = 438

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  ALTAYT 9
          ALTAYT
Sbjct: 59 ALTAYT 64
>NP_060434
          Length = 461

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  ALTAYT 9
          ALTAYT
Sbjct: 59 ALTAYT 64
>NP_056197
          Length = 2610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    STSALTAYT 9
            STS LTA T
Sbjct: 1447 STSTLTAET 1455
>NP_065770
          Length = 2036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   STSALTAY 8
           S+SAL+AY
Sbjct: 144 SSSALSAY 151
>NP_001180444
          Length = 432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  ALTAYT 9
          ALTAYT
Sbjct: 30 ALTAYT 35
>XP_006724993
          Length = 569

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 422 TTSALPAFT 430
>XP_006724992
          Length = 252

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  STSALTAYT 9
          +TSAL A+T
Sbjct: 78 TTSALPAFT 86
>XP_006724991
          Length = 321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 147 TTSALPAFT 155
>XP_006724990
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 229 TTSALPAFT 237
>XP_006724989
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 229 TTSALPAFT 237
>XP_006724988
          Length = 439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 265 TTSALPAFT 273
>XP_006724987
          Length = 439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 265 TTSALPAFT 273
>XP_006724986
          Length = 488

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 314 TTSALPAFT 322
>XP_006724985
          Length = 496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 322 TTSALPAFT 330
>XP_006724984
          Length = 517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 343 TTSALPAFT 351
>XP_006724983
          Length = 525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 378 TTSALPAFT 386
>XP_006724982
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 391 TTSALPAFT 399
>XP_006724981
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 391 TTSALPAFT 399
>XP_006724980
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 391 TTSALPAFT 399
>XP_006724979
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 391 TTSALPAFT 399
>XP_006724978
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 391 TTSALPAFT 399
>XP_006724977
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 391 TTSALPAFT 399
>XP_006724976
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 391 TTSALPAFT 399
>XP_006724460
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 427 TTSALPAFT 435
>XP_006724459
          Length = 252

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  STSALTAYT 9
          +TSAL A+T
Sbjct: 78 TTSALPAFT 86
>XP_005261947
          Length = 321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 147 TTSALPAFT 155
>XP_006724458
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 229 TTSALPAFT 237
>XP_005261945
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 229 TTSALPAFT 237
>XP_006724457
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 229 TTSALPAFT 237
>XP_006724456
          Length = 412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 265 TTSALPAFT 273
>XP_006724455
          Length = 439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STSALTAYT 9
           +TSAL A+T
Sbjct: 265 TTSALPAFT 273
>XP_005267560
          Length = 2563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    STSALTAYT 9
            STS LTA T
Sbjct: 1400 STSTLTAET 1408
>XP_005267559
          Length = 2610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    STSALTAYT 9
            STS LTA T
Sbjct: 1447 STSTLTAET 1455
>XP_006712109
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  ALTAYT 9
          ALTAYT
Sbjct: 59 ALTAYT 64
>NP_061836
          Length = 2320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    STSALTAY 8
            STS+ TAY
Sbjct: 1479 STSSRTAY 1486
>NP_387505
          Length = 2269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    STSALTAY 8
            STS+ TAY
Sbjct: 1479 STSSRTAY 1486
>XP_005261051
          Length = 2242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    STSALTAY 8
            STS+ TAY
Sbjct: 1401 STSSRTAY 1408
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295   0.0971    0.229 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 272,628
Number of extensions: 261
Number of successful extensions: 43
Number of sequences better than 10000.0: 43
Number of HSP's gapped: 43
Number of HSP's successfully gapped: 43
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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