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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001121619                                                           18    1482
NP_000258                                                              18    1482
NP_001035957                                                           18    1482
XP_006721991                                                           18    1482
XP_006721990                                                           18    1482
XP_006721989                                                           18    1482
XP_005258041                                                           18    1482
XP_006721988                                                           18    1482
XP_006721987                                                           18    1482
XP_006721986                                                           18    1482
XP_005258040                                                           18    1482
XP_006721985                                                           18    1482
NP_067077                                                              17    4312
NP_000128                                                              16    5631
NP_775837                                                              16    7355
XP_006724284                                                           16    7355
XP_006724283                                                           16    7355
XP_006724282                                                           16    7355
XP_005261537                                                           16    7355
NP_001269109                                                           15    9605
NP_001036167                                                           15    9605
NP_006237                                                              15    9605
NP_001269111                                                           15    9605
NP_001269110                                                           15    9605
NP_001269108                                                           15    9605
NP_078801                                                              15    9605
XP_005246686                                                           15    9605
XP_006712617                                                           15    9605
XP_005246685                                                           15    9605
XP_005246684                                                           15    9605
XP_005246683                                                           15    9605
XP_005264439                                                           15    9605
XP_005264438                                                           15    9605
XP_006711877                                                           15    9605
XP_005273321                                                           15    9605
XP_005273318                                                           15    9605
XP_005273317                                                           15    9605
NP_060197                                                              15    9605

>NP_001121619
          Length = 593

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STMLQELTV 9
           ST LQELTV
Sbjct: 158 STRLQELTV 166



>NP_000258
          Length = 2818

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STMLQELTV 9
           ST LQELTV
Sbjct: 158 STRLQELTV 166



>NP_001035957
          Length = 2839

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STMLQELTV 9
           ST LQELTV
Sbjct: 158 STRLQELTV 166



>XP_006721991
          Length = 1632

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STMLQELTV 9
           ST LQELTV
Sbjct: 158 STRLQELTV 166



>XP_006721990
          Length = 2823

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STMLQELTV 9
           ST LQELTV
Sbjct: 158 STRLQELTV 166



>XP_006721989
          Length = 2823

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STMLQELTV 9
           ST LQELTV
Sbjct: 158 STRLQELTV 166



>XP_005258041
          Length = 2836

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STMLQELTV 9
           ST LQELTV
Sbjct: 158 STRLQELTV 166



>XP_006721988
          Length = 2846

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STMLQELTV 9
           ST LQELTV
Sbjct: 158 STRLQELTV 166



>XP_006721987
          Length = 2849

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STMLQELTV 9
           ST LQELTV
Sbjct: 158 STRLQELTV 166



>XP_006721986
          Length = 2854

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STMLQELTV 9
           ST LQELTV
Sbjct: 145 STRLQELTV 153



>XP_005258040
          Length = 2857

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STMLQELTV 9
           ST LQELTV
Sbjct: 158 STRLQELTV 166



>XP_006721985
          Length = 2867

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STMLQELTV 9
           ST LQELTV
Sbjct: 158 STRLQELTV 166



>NP_067077
          Length = 290

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  STMLQELTV 9
          ST L+ELTV
Sbjct: 21 STELEELTV 29



>NP_000128
          Length = 419

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TMLQELT 8
           TMLQ+LT
Sbjct: 325 TMLQQLT 331



>NP_775837
          Length = 2151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    STMLQELTV 9
            STM+ E+T+
Sbjct: 1441 STMINEITL 1449



>XP_006724284
          Length = 1989

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    STMLQELTV 9
            STM+ E+T+
Sbjct: 1279 STMINEITL 1287



>XP_006724283
          Length = 2151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    STMLQELTV 9
            STM+ E+T+
Sbjct: 1441 STMINEITL 1449



>XP_006724282
          Length = 2151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    STMLQELTV 9
            STM+ E+T+
Sbjct: 1441 STMINEITL 1449



>XP_005261537
          Length = 2151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    STMLQELTV 9
            STM+ E+T+
Sbjct: 1441 STMINEITL 1449



>NP_001269109
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   STMLQELT 8
           STM  ELT
Sbjct: 419 STMFDELT 426



>NP_001036167
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   STMLQELT 8
           ST+L+E+T
Sbjct: 127 STLLKEIT 134



>NP_006237
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   STMLQELT 8
           STM  ELT
Sbjct: 419 STMFDELT 426



>NP_001269111
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   STMLQELT 8
           STM  ELT
Sbjct: 343 STMFDELT 350



>NP_001269110
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   STMLQELT 8
           STM  ELT
Sbjct: 343 STMFDELT 350



>NP_001269108
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   STMLQELT 8
           STM  ELT
Sbjct: 419 STMFDELT 426



>NP_078801
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   STMLQE 6
           STMLQE
Sbjct: 167 STMLQE 172



>XP_005246686
          Length = 349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   STMLQELT 8
           ST+L+E+T
Sbjct: 124 STLLKEIT 131



>XP_006712617
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   STMLQELT 8
           ST+L+E+T
Sbjct: 127 STLLKEIT 134



>XP_005246685
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   STMLQELT 8
           ST+L+E+T
Sbjct: 162 STLLKEIT 169



>XP_005246684
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   STMLQELT 8
           ST+L+E+T
Sbjct: 130 STLLKEIT 137



>XP_005246683
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   STMLQELT 8
           ST+L+E+T
Sbjct: 162 STLLKEIT 169



>XP_005264439
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TMLQEL 7
           TMLQEL
Sbjct: 203 TMLQEL 208



>XP_005264438
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TMLQEL 7
           TMLQEL
Sbjct: 203 TMLQEL 208



>XP_006711877
          Length = 781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   STMLQE 6
           STMLQE
Sbjct: 167 STMLQE 172



>XP_005273321
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   STMLQE 6
           STMLQE
Sbjct: 167 STMLQE 172



>XP_005273318
          Length = 829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   STMLQE 6
           STMLQE
Sbjct: 167 STMLQE 172



>XP_005273317
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   STMLQE 6
           STMLQE
Sbjct: 167 STMLQE 172



>NP_060197
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TMLQEL 7
           TMLQEL
Sbjct: 203 TMLQEL 208



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.117    0.265 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 463,206
Number of extensions: 499
Number of successful extensions: 38
Number of sequences better than 10000.0: 38
Number of HSP's gapped: 38
Number of HSP's successfully gapped: 38
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)