Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001273052                                                           17    2528
NP_001273054                                                           17    2528
NP_005826                                                              17    2528
XP_006715015                                                           17    2528
XP_006715014                                                           17    2528
XP_006715013                                                           17    2528
XP_006715012                                                           17    2528
XP_005248841                                                           17    2528
NP_115518                                                              17    4312
XP_006722394                                                           17    4312
XP_005258167                                                           17    4312
XP_006722393                                                           17    4312
XP_006722392                                                           17    4312
XP_006722391                                                           17    4312
XP_006722390                                                           17    4312
XP_005258166                                                           17    4312
XP_006722389                                                           17    4312
XP_005258165                                                           17    4312
XP_005258164                                                           17    4312
NP_060395                                                              16    5631
XP_006716870                                                           16    5631
XP_006716869                                                           16    5631
XP_006716868                                                           16    5631
XP_006716867                                                           16    5631
NP_055463                                                              16    7355
XP_005247976                                                           16    7355
XP_005247975                                                           16    7355
XP_005247974                                                           16    7355
XP_005247973                                                           16    7355
XP_005247972                                                           16    7355
XP_005247971                                                           16    7355
XP_006711599                                                           16    7355
XP_005245543                                                           16    7355
XP_006711598                                                           16    7355
XP_006711597                                                           16    7355
XP_006711596                                                           16    7355
XP_006711595                                                           16    7355
XP_006711594                                                           16    7355
NP_110391                                                              16    7355
NP_001243040                                                           15    9605
NP_001243035                                                           15    9605
NP_004249                                                              15    9605
NP_001243038                                                           15    9605
NP_001254505                                                           15    9605
NP_694942                                                              15    9605
>NP_001273052
          Length = 478

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TKAAVFSW 9
          TKA+V+ W
Sbjct: 79 TKASVYQW 86
>NP_001273054
          Length = 398

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TKAAVFSW 9
          TKA+V+ W
Sbjct: 79 TKASVYQW 86
>NP_005826
          Length = 436

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TKAAVFSW 9
          TKA+V+ W
Sbjct: 79 TKASVYQW 86
>XP_006715015
          Length = 356

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TKAAVFSW 9
          TKA+V+ W
Sbjct: 79 TKASVYQW 86
>XP_006715014
          Length = 398

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TKAAVFSW 9
          TKA+V+ W
Sbjct: 79 TKASVYQW 86
>XP_006715013
          Length = 455

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TKAAVFSW 9
          TKA+V+ W
Sbjct: 56 TKASVYQW 63
>XP_006715012
          Length = 478

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TKAAVFSW 9
          TKA+V+ W
Sbjct: 79 TKASVYQW 86
>XP_005248841
          Length = 478

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TKAAVFSW 9
          TKA+V+ W
Sbjct: 79 TKASVYQW 86
>NP_115518
          Length = 2537

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    STKAAVFSW 9
            STK ++F W
Sbjct: 2200 STKQSMFPW 2208
>XP_006722394
          Length = 1845

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    STKAAVFSW 9
            STK ++F W
Sbjct: 1507 STKQSMFPW 1515
>XP_005258167
          Length = 1856

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    STKAAVFSW 9
            STK ++F W
Sbjct: 1518 STKQSMFPW 1526
>XP_006722393
          Length = 2199

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    STKAAVFSW 9
            STK ++F W
Sbjct: 1861 STKQSMFPW 1869
>XP_006722392
          Length = 2444

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    STKAAVFSW 9
            STK ++F W
Sbjct: 2106 STKQSMFPW 2114
>XP_006722391
          Length = 2448

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    STKAAVFSW 9
            STK ++F W
Sbjct: 2110 STKQSMFPW 2118
>XP_006722390
          Length = 2467

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    STKAAVFSW 9
            STK ++F W
Sbjct: 2130 STKQSMFPW 2138
>XP_005258166
          Length = 2468

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    STKAAVFSW 9
            STK ++F W
Sbjct: 2130 STKQSMFPW 2138
>XP_006722389
          Length = 2506

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    STKAAVFSW 9
            STK ++F W
Sbjct: 2200 STKQSMFPW 2208
>XP_005258165
          Length = 2534

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    STKAAVFSW 9
            STK ++F W
Sbjct: 2196 STKQSMFPW 2204
>XP_005258164
          Length = 2538

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    STKAAVFSW 9
            STK ++F W
Sbjct: 2200 STKQSMFPW 2208
>NP_060395
          Length = 1909

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   STKAAVFSW 9
           ST++ +F W
Sbjct: 873 STRSGIFLW 881
>XP_006716870
          Length = 1456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   STKAAVFSW 9
           ST++ +F W
Sbjct: 371 STRSGIFLW 379
>XP_006716869
          Length = 1722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   STKAAVFSW 9
           ST++ +F W
Sbjct: 637 STRSGIFLW 645
>XP_006716868
          Length = 1894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   STKAAVFSW 9
           ST++ +F W
Sbjct: 873 STRSGIFLW 881
>XP_006716867
          Length = 1958

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   STKAAVFSW 9
           ST++ +F W
Sbjct: 873 STRSGIFLW 881
>NP_055463
          Length = 1208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KAAVFSW 9
           KAAV SW
Sbjct: 906 KAAVDSW 912
>XP_005247976
          Length = 1002

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KAAVFSW 9
           KAAV SW
Sbjct: 700 KAAVDSW 706
>XP_005247975
          Length = 1208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KAAVFSW 9
           KAAV SW
Sbjct: 906 KAAVDSW 912
>XP_005247974
          Length = 1208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KAAVFSW 9
           KAAV SW
Sbjct: 906 KAAVDSW 912
>XP_005247973
          Length = 1208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KAAVFSW 9
           KAAV SW
Sbjct: 906 KAAVDSW 912
>XP_005247972
          Length = 1208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KAAVFSW 9
           KAAV SW
Sbjct: 906 KAAVDSW 912
>XP_005247971
          Length = 1208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KAAVFSW 9
           KAAV SW
Sbjct: 906 KAAVDSW 912
>XP_006711599
          Length = 185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  STKAAVFSW 9
          STK  +F W
Sbjct: 83 STKGQLFLW 91
>XP_005245543
          Length = 202

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  STKAAVFSW 9
          STK  +F W
Sbjct: 83 STKGQLFLW 91
>XP_006711598
          Length = 313

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  STKAAVFSW 9
          STK  +F W
Sbjct: 83 STKGQLFLW 91
>XP_006711597
          Length = 319

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  STKAAVFSW 9
          STK  +F W
Sbjct: 83 STKGQLFLW 91
>XP_006711596
          Length = 413

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  STKAAVFSW 9
          STK  +F W
Sbjct: 83 STKGQLFLW 91
>XP_006711595
          Length = 415

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  STKAAVFSW 9
          STK  +F W
Sbjct: 83 STKGQLFLW 91
>XP_006711594
          Length = 442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  STKAAVFSW 9
          STK  +F W
Sbjct: 83 STKGQLFLW 91
>NP_110391
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  STKAAVFSW 9
          STK  +F W
Sbjct: 83 STKGQLFLW 91
>NP_001243040
          Length = 959

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  STKAAVFSW 9
          STK A FS+
Sbjct: 74 STKDAAFSY 82
>NP_001243035
          Length = 1021

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  STKAAVFSW 9
          STK A FS+
Sbjct: 74 STKDAAFSY 82
>NP_004249
          Length = 1021

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  STKAAVFSW 9
          STK A FS+
Sbjct: 74 STKDAAFSY 82
>NP_001243038
          Length = 1021

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  STKAAVFSW 9
          STK A FS+
Sbjct: 74 STKDAAFSY 82
>NP_001254505
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   STKAAVFSW 9
           ST+ ++ SW
Sbjct: 739 STRGSLLSW 747
>NP_694942
          Length = 1123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   STKAAVFSW 9
           ST+ ++ SW
Sbjct: 744 STRGSLLSW 752
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.112    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 342,424
Number of extensions: 392
Number of successful extensions: 45
Number of sequences better than 10000.0: 45
Number of HSP's gapped: 45
Number of HSP's successfully gapped: 45
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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