Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001257436                                                           21     229
NP_001257437                                                           21     229
NP_006281                                                              21     229
XP_005267176                                                           21     229
XP_006726560                                                           17    2528
NP_055383                                                              16    5631
NP_056227                                                              16    5631
NP_060493                                                              16    5631
XP_006713751                                                           16    5631
XP_005247655                                                           16    5631
XP_005247654                                                           16    5631
XP_005247335                                                           16    5631
XP_005247333                                                           16    5631
XP_005247330                                                           16    5631
NP_001006608                                                           16    7355
NP_955372                                                              16    7355
NP_055649                                                              16    7355
XP_005275726                                                           16    7355
XP_006725346                                                           16    7355
XP_006725345                                                           16    7355
XP_006725344                                                           16    7355
XP_005275719                                                           16    7355
XP_006725343                                                           16    7355
XP_006725342                                                           16    7355
XP_005275717                                                           16    7355
XP_005275716                                                           16    7355
XP_006722276                                                           16    7355
XP_006722275                                                           16    7355
XP_005257944                                                           16    7355
XP_006722274                                                           16    7355
XP_006722273                                                           16    7355
XP_005257939                                                           16    7355
XP_006722272                                                           16    7355
XP_005257937                                                           16    7355
XP_005257936                                                           16    7355
XP_005257935                                                           16    7355
XP_006722271                                                           16    7355
NP_062824                                                              15    9605
NP_001107562                                                           15    9605
NP_878918                                                              15    9605
NP_055995                                                              15    9605
NP_573400                                                              15    9605
NP_008981                                                              15    9605
NP_004720                                                              15    9605
NP_001164607                                                           15    9605
NP_001164606                                                           15    9605
XP_006723752                                                           15    9605
XP_006723751                                                           15    9605
XP_006723750                                                           15    9605
XP_006723749                                                           15    9605
XP_006723748                                                           15    9605
XP_005267517                                                           15    9605
XP_005267516                                                           15    9605
XP_005267515                                                           15    9605
XP_005267514                                                           15    9605
XP_005267513                                                           15    9605
XP_005267512                                                           15    9605
XP_005267511                                                           15    9605
>NP_001257436
          Length = 790

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   STIKETDTR 9
           ST+KETDTR
Sbjct: 128 STLKETDTR 136
>NP_001257437
          Length = 790

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   STIKETDTR 9
           ST+KETDTR
Sbjct: 128 STLKETDTR 136
>NP_006281
          Length = 790

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   STIKETDTR 9
           ST+KETDTR
Sbjct: 128 STLKETDTR 136
>XP_005267176
          Length = 790

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   STIKETDTR 9
           ST+KETDTR
Sbjct: 128 STLKETDTR 136
>XP_006726560
          Length = 197

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  TIKETDT 8
          T+KETDT
Sbjct: 32 TLKETDT 38
>NP_055383
          Length = 940

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   IKETDT 8
           IKETDT
Sbjct: 659 IKETDT 664
>NP_056227
          Length = 567

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TIKETD 7
           TIKETD
Sbjct: 551 TIKETD 556
>NP_060493
          Length = 1422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  TIKETD 7
          TIKETD
Sbjct: 7  TIKETD 12
>XP_006713751
          Length = 1423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  TIKETD 7
          TIKETD
Sbjct: 7  TIKETD 12
>XP_005247655
          Length = 1423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  TIKETD 7
          TIKETD
Sbjct: 7  TIKETD 12
>XP_005247654
          Length = 1423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  TIKETD 7
          TIKETD
Sbjct: 7  TIKETD 12
>XP_005247335
          Length = 400

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TIKETD 7
           TIKETD
Sbjct: 384 TIKETD 389
>XP_005247333
          Length = 431

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TIKETD 7
           TIKETD
Sbjct: 415 TIKETD 420
>XP_005247330
          Length = 497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TIKETD 7
           TIKETD
Sbjct: 481 TIKETD 486
>NP_001006608
          Length = 1700

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1437 TVKQTETK 1444
>NP_955372
          Length = 1634

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1437 TVKQTETK 1444
>NP_055649
          Length = 1700

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1437 TVKQTETK 1444
>XP_005275726
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   TIKETDTR 9
           T+K+T+T+
Sbjct: 443 TVKQTETK 450
>XP_006725346
          Length = 839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   TIKETDTR 9
           T+K+T+T+
Sbjct: 576 TVKQTETK 583
>XP_006725345
          Length = 1600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1337 TVKQTETK 1344
>XP_006725344
          Length = 1606

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1343 TVKQTETK 1350
>XP_005275719
          Length = 1625

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1362 TVKQTETK 1369
>XP_006725343
          Length = 1635

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1437 TVKQTETK 1444
>XP_006725342
          Length = 1651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1388 TVKQTETK 1395
>XP_005275717
          Length = 1665

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1437 TVKQTETK 1444
>XP_005275716
          Length = 1676

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1413 TVKQTETK 1420
>XP_006722276
          Length = 630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   TIKETDTR 9
           T+K+T+T+
Sbjct: 367 TVKQTETK 374
>XP_006722275
          Length = 630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   TIKETDTR 9
           T+K+T+T+
Sbjct: 367 TVKQTETK 374
>XP_005257944
          Length = 839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   TIKETDTR 9
           T+K+T+T+
Sbjct: 576 TVKQTETK 583
>XP_006722274
          Length = 1576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1313 TVKQTETK 1320
>XP_006722273
          Length = 1600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1337 TVKQTETK 1344
>XP_005257939
          Length = 1606

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1343 TVKQTETK 1350
>XP_006722272
          Length = 1635

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1437 TVKQTETK 1444
>XP_005257937
          Length = 1651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1388 TVKQTETK 1395
>XP_005257936
          Length = 1665

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1437 TVKQTETK 1444
>XP_005257935
          Length = 1676

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1413 TVKQTETK 1420
>XP_006722271
          Length = 1700

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    TIKETDTR 9
            T+K+T+T+
Sbjct: 1437 TVKQTETK 1444
>NP_062824
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   STIKETDTR 9
           ST++E +TR
Sbjct: 186 STLQEIETR 194
>NP_001107562
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   STIKETDTR 9
           ST++E +TR
Sbjct: 94  STLQEIETR 102
>NP_878918
          Length = 6907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    IKETDT 8
            +KETDT
Sbjct: 5018 LKETDT 5023
>NP_055995
          Length = 6885

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    IKETDT 8
            +KETDT
Sbjct: 5018 LKETDT 5023
>NP_573400
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   TIKETDT 8
           T+KE DT
Sbjct: 94  TLKENDT 100
>NP_008981
          Length = 1441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   TIKETDT 8
           T+KE DT
Sbjct: 94  TLKENDT 100
>NP_004720
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IKETDTR 9
           IKETD++
Sbjct: 436 IKETDSK 442
>NP_001164607
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IKETDTR 9
           IKETD++
Sbjct: 436 IKETDSK 442
>NP_001164606
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IKETDTR 9
           IKETD++
Sbjct: 436 IKETDSK 442
>XP_006723752
          Length = 1387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  TIKETDT 8
          T+KE DT
Sbjct: 31 TLKENDT 37
>XP_006723751
          Length = 1427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  TIKETDT 8
          T+KE DT
Sbjct: 20 TLKENDT 26
>XP_006723750
          Length = 1427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  TIKETDT 8
          T+KE DT
Sbjct: 20 TLKENDT 26
>XP_006723749
          Length = 1428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  TIKETDT 8
          T+KE DT
Sbjct: 31 TLKENDT 37
>XP_006723748
          Length = 1437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  TIKETDT 8
          T+KE DT
Sbjct: 31 TLKENDT 37
>XP_005267517
          Length = 6883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    IKETDT 8
            +KETDT
Sbjct: 4979 LKETDT 4984
>XP_005267516
          Length = 6884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    IKETDT 8
            +KETDT
Sbjct: 5018 LKETDT 5023
>XP_005267515
          Length = 6899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    IKETDT 8
            +KETDT
Sbjct: 5018 LKETDT 5023
>XP_005267514
          Length = 6908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    IKETDT 8
            +KETDT
Sbjct: 5018 LKETDT 5023
>XP_005267513
          Length = 6921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    IKETDT 8
            +KETDT
Sbjct: 5018 LKETDT 5023
>XP_005267512
          Length = 6922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    IKETDT 8
            +KETDT
Sbjct: 5018 LKETDT 5023
>XP_005267511
          Length = 6922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    IKETDT 8
            +KETDT
Sbjct: 5018 LKETDT 5023
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.296    0.111    0.264 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 495,053
Number of extensions: 843
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package