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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_076955                                                              19     665
NP_001136156                                                           16    5631
NP_001034739                                                           16    5631
XP_005266651                                                           16    5631
XP_006719957                                                           16    5631
XP_005266650                                                           16    5631
NP_065822                                                              16    7355
NP_006651                                                              16    7355
NP_056052                                                              16    7355
XP_005267130                                                           16    7355
XP_006715593                                                           16    7355
XP_005267128                                                           16    7355
XP_006715592                                                           16    7355
XP_006715591                                                           16    7355
NP_001153059                                                           15    9605
NP_001153060                                                           15    9605
NP_598000                                                              15    9605
NP_001245245                                                           15    9605
NP_060568                                                              15    9605
NP_001245244                                                           15    9605
NP_620155                                                              15    9605
NP_001138883                                                           15    9605
NP_001157936                                                           15    9605
NP_060639                                                              15    9605
XP_006719162                                                           15    9605
XP_005253462                                                           15    9605
XP_005248716                                                           15    9605
XP_006714236                                                           15    9605
XP_005262948                                                           15    9605
XP_006714235                                                           15    9605
XP_005247237                                                           15    9605
XP_006713587                                                           15    9605
XP_005247233                                                           15    9605
XP_006713586                                                           15    9605
XP_006712770                                                           15    9605
XP_006712325                                                           15    9605
NP_689988                                                              15    9605

>NP_076955
          Length = 102

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  TEKTNILL 9
          TEKTNILL
Sbjct: 49 TEKTNILL 56



>NP_001136156
          Length = 669

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   STEKTNILL 9
           ST+K N++L
Sbjct: 294 STKKANVIL 302



>NP_001034739
          Length = 382

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   STEKTNILL 9
           ST+K N++L
Sbjct: 294 STKKANVIL 302



>XP_005266651
          Length = 669

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   STEKTNILL 9
           ST+K N++L
Sbjct: 294 STKKANVIL 302



>XP_006719957
          Length = 669

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   STEKTNILL 9
           ST+K N++L
Sbjct: 294 STKKANVIL 302



>XP_005266650
          Length = 669

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   STEKTNILL 9
           ST+K N++L
Sbjct: 294 STKKANVIL 302



>NP_065822
          Length = 909

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   STEKTNILL 9
           STE T+ILL
Sbjct: 385 STEITSILL 393



>NP_006651
          Length = 633

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EKTNILL 9
           EK+NILL
Sbjct: 285 EKSNILL 291



>NP_056052
          Length = 1354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    STEKTNILL 9
            +TEK NI L
Sbjct: 1189 TTEKANIAL 1197



>XP_005267130
          Length = 573

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   STEKTNILL 9
           STE T+ILL
Sbjct: 385 STEITSILL 393



>XP_006715593
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   STEKTNILL 9
           STE T+ILL
Sbjct: 217 STEITSILL 225



>XP_005267128
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   STEKTNILL 9
           STE T+ILL
Sbjct: 217 STEITSILL 225



>XP_006715592
          Length = 865

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   STEKTNILL 9
           STE T+ILL
Sbjct: 341 STEITSILL 349



>XP_006715591
          Length = 875

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   STEKTNILL 9
           STE T+ILL
Sbjct: 351 STEITSILL 359



>NP_001153059
          Length = 1428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    STEKTNI 7
            +TE+TNI
Sbjct: 1199 NTERTNI 1205



>NP_001153060
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    STEKTNI 7
            +TE+TNI
Sbjct: 1122 NTERTNI 1128



>NP_598000
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    STEKTNI 7
            +TE+TNI
Sbjct: 1199 NTERTNI 1205



>NP_001245245
          Length = 883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TEKTNILL 9
           TE+ N+LL
Sbjct: 731 TEQANVLL 738



>NP_060568
          Length = 883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TEKTNILL 9
           TE+ N+LL
Sbjct: 731 TEQANVLL 738



>NP_001245244
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TEKTNILL 9
           TE+ N+LL
Sbjct: 762 TEQANVLL 769



>NP_620155
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  KTNILL 9
          KTNILL
Sbjct: 65 KTNILL 70



>NP_001138883
          Length = 796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KTNILL 9
           KTNILL
Sbjct: 538 KTNILL 543



>NP_001157936
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  KTNILL 9
          KTNILL
Sbjct: 65 KTNILL 70



>NP_060639
          Length = 1747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    STEKTNIL 8
            +TEK+N+L
Sbjct: 1626 NTEKSNML 1633



>XP_006719162
          Length = 1676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    STEKTNIL 8
            +TEK+N+L
Sbjct: 1626 NTEKSNML 1633



>XP_005253462
          Length = 1747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    STEKTNIL 8
            +TEK+N+L
Sbjct: 1626 NTEKSNML 1633



>XP_005248716
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    STEKTNI 7
            +TE+TNI
Sbjct: 1199 NTERTNI 1205



>XP_006714236
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KTNILL 9
           KTNILL
Sbjct: 505 KTNILL 510



>XP_005262948
          Length = 836

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KTNILL 9
           KTNILL
Sbjct: 575 KTNILL 580



>XP_006714235
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KTNILL 9
           KTNILL
Sbjct: 575 KTNILL 580



>XP_005247237
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TEKTNILL 9
           TE+ N+LL
Sbjct: 561 TEQANVLL 568



>XP_006713587
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TEKTNILL 9
           TE+ N+LL
Sbjct: 762 TEQANVLL 769



>XP_005247233
          Length = 927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TEKTNILL 9
           TE+ N+LL
Sbjct: 731 TEQANVLL 738



>XP_006713586
          Length = 958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TEKTNILL 9
           TE+ N+LL
Sbjct: 762 TEQANVLL 769



>XP_006712770
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  KTNILL 9
          KTNILL
Sbjct: 65 KTNILL 70



>XP_006712325
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  KTNILL 9
          KTNILL
Sbjct: 65 KTNILL 70



>NP_689988
          Length = 833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KTNILL 9
           KTNILL
Sbjct: 575 KTNILL 580



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.301    0.119    0.277 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 429,442
Number of extensions: 756
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)