Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001257436                                                           22     134
NP_001257437                                                           22     134
NP_006281                                                              22     134
XP_006715618                                                           22     134
XP_005267176                                                           22     134
NP_112237                                                              17    2528
NP_001264261                                                           17    2528
NP_114169                                                              17    2528
XP_006726379                                                           17    2528
XP_005257690                                                           17    2528
NP_001177389                                                           17    2528
NP_149461                                                              17    2528
NP_114167                                                              17    2528
NP_001269557                                                           17    4312
NP_001269560                                                           17    4312
NP_000038                                                              17    4312
NP_001451                                                              17    4312
XP_005276327                                                           17    4312
XP_005274578                                                           17    4312
XP_005274576                                                           17    4312
XP_005274575                                                           17    4312
XP_006714808                                                           17    4312
XP_005245096                                                           17    4312
XP_006710231                                                           17    4312
NP_001058                                                              16    5631
NP_938015                                                              16    5631
NP_001245344                                                           16    5631
NP_055509                                                              16    5631
NP_001138792                                                           16    5631
NP_065860                                                              16    5631
NP_001245347                                                           16    5631
NP_001245346                                                           16    5631
NP_001245345                                                           16    5631
NP_060009                                                              16    5631
NP_001059                                                              16    5631
XP_006722199                                                           16    5631
XP_005257785                                                           16    5631
XP_005257689                                                           16    5631
XP_006721125                                                           16    5631
XP_005271685                                                           16    5631
XP_006718956                                                           16    5631
XP_005272296                                                           16    5631
XP_006717400                                                           16    5631
XP_005272295                                                           16    5631
XP_006717399                                                           16    5631
XP_005272294                                                           16    5631
XP_005265484                                                           16    5631
XP_005264213                                                           16    5631
NP_787054                                                              16    5631
NP_115510                                                              16    5631
NP_689418                                                              16    7355
NP_003817                                                              16    7355
NP_002967                                                              16    7355
NP_003301                                                              16    7355
XP_006712745                                                           16    7355
XP_006712744                                                           16    7355
XP_006712743                                                           16    7355
XP_005273217                                                           16    7355
NP_149040                                                              16    7355
NP_114168                                                              16    7355
NP_061947                                                              15    9605
NP_001124162                                                           15    9605
NP_057004                                                              15    9605
NP_001092806                                                           15    9605
NP_004676                                                              15    9605
NP_940923                                                              15    9605
NP_001264260                                                           15    9605
XP_006719955                                                           15    9605
XP_006719444                                                           15    9605
XP_006719124                                                           15    9605
XP_005253405                                                           15    9605
XP_005247497                                                           15    9605
NP_001021                                                              15    9605
NP_001078889                                                           15    9605
NP_777601                                                              15    9605
>NP_001257436
          Length = 790

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   STCFKRTT 8
           STCFKRTT
Sbjct: 537 STCFKRTT 544
>NP_001257437
          Length = 790

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   STCFKRTT 8
           STCFKRTT
Sbjct: 537 STCFKRTT 544
>NP_006281
          Length = 790

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   STCFKRTT 8
           STCFKRTT
Sbjct: 537 STCFKRTT 544
>XP_006715618
          Length = 577

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   STCFKRTT 8
           STCFKRTT
Sbjct: 324 STCFKRTT 331
>XP_005267176
          Length = 790

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   STCFKRTT 8
           STCFKRTT
Sbjct: 537 STCFKRTT 544
>NP_112237
          Length = 169

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  STCFKRTTV 9
          +TC+K TTV
Sbjct: 16 TTCWKPTTV 24
>NP_001264261
          Length = 169

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  STCFKRTTV 9
          +TC+K TTV
Sbjct: 16 TTCWKPTTV 24
>NP_114169
          Length = 159

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  STCFKRTTV 9
          +TC+K TTV
Sbjct: 16 TTCWKPTTV 24

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   TCFKRTTV 9
           TC+  TTV
Sbjct: 104 TCYHPTTV 111
>XP_006726379
          Length = 174

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  STCFKRTTV 9
          +TC+K TTV
Sbjct: 21 TTCWKPTTV 29
>XP_005257690
          Length = 188

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  STCFKRTTV 9
          +TC+K TTV
Sbjct: 21 TTCWKPTTV 29
>NP_001177389
          Length = 250

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  STCFKRTTV 9
          +TC+K TTV
Sbjct: 21 TTCWKPTTV 29
>NP_149461
          Length = 154

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  STCFKRTTV 9
          +TC+K TTV
Sbjct: 21 TTCWKPTTV 29
>NP_114167
          Length = 174

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  STCFKRTTV 9
          +TC+K TTV
Sbjct: 21 TTCWKPTTV 29
>NP_001269557
          Length = 614

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CFKRTT 8
           CF+RTT
Sbjct: 292 CFQRTT 297
>NP_001269560
          Length = 544

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CFKRTT 8
           CF+RTT
Sbjct: 222 CFQRTT 227
>NP_000038
          Length = 589

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CFKRTT 8
           CF+RTT
Sbjct: 267 CFQRTT 272
>NP_001451
          Length = 471

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  TCFKRT 7
          TCF+RT
Sbjct: 29 TCFERT 34
>XP_005276327
          Length = 289

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   CFKRTTV 9
           CF RTTV
Sbjct: 240 CFCRTTV 246
>XP_005274578
          Length = 535

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CFKRTT 8
           CF+RTT
Sbjct: 213 CFQRTT 218
>XP_005274576
          Length = 589

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CFKRTT 8
           CF+RTT
Sbjct: 267 CFQRTT 272
>XP_005274575
          Length = 598

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CFKRTT 8
           CF+RTT
Sbjct: 276 CFQRTT 281
>XP_006714808
          Length = 222

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   CFKRTTV 9
           CF RTTV
Sbjct: 127 CFCRTTV 133
>XP_005245096
          Length = 416

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  TCFKRT 7
          TCF+RT
Sbjct: 29 TCFERT 34
>XP_006710231
          Length = 222

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   CFKRTTV 9
           CF RTTV
Sbjct: 127 CFCRTTV 133
>NP_001058
          Length = 1531

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 2   TCFKR 6
           TCFKR
Sbjct: 732 TCFKR 736
>NP_938015
          Length = 490

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 2  TCFKR 6
          TCFKR
Sbjct: 54 TCFKR 58
>NP_001245344
          Length = 1168

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TCFKRTTV 9
           TCFK++ V
Sbjct: 732 TCFKQSLV 739
>NP_055509
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   STCFKR 6
           STCF+R
Sbjct: 847 STCFER 852
>NP_001138792
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   STCFKR 6
           STCF+R
Sbjct: 847 STCFER 852
>NP_065860
          Length = 1191

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TCFKRTTV 9
           TCFK++ V
Sbjct: 755 TCFKQSLV 762
>NP_001245347
          Length = 1155

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TCFKRTTV 9
           TCFK++ V
Sbjct: 719 TCFKQSLV 726
>NP_001245346
          Length = 1155

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TCFKRTTV 9
           TCFK++ V
Sbjct: 719 TCFKQSLV 726
>NP_001245345
          Length = 1165

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TCFKRTTV 9
           TCFK++ V
Sbjct: 729 TCFKQSLV 736
>NP_060009
          Length = 4116

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    STCFKRT 7
            S CFK+T
Sbjct: 2333 SNCFKQT 2339
>NP_001059
          Length = 1621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 2   TCFKR 6
           TCFKR
Sbjct: 748 TCFKR 752
>XP_006722199
          Length = 641

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   STCFKRTT 8
           S C+KR T
Sbjct: 455 SPCYKRVT 462
>XP_005257785
          Length = 1887

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    STCFKRTT 8
            S C+KR T
Sbjct: 1701 SPCYKRVT 1708
>XP_005257689
          Length = 1519

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 2   TCFKR 6
           TCFKR
Sbjct: 720 TCFKR 724
>XP_006721125
          Length = 4070

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    STCFKRT 7
            S CFK+T
Sbjct: 2287 SNCFKQT 2293
>XP_005271685
          Length = 734

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TCFKRTTV 9
           TCFK++ V
Sbjct: 298 TCFKQSLV 305
>XP_006718956
          Length = 1191

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TCFKRTTV 9
           TCFK++ V
Sbjct: 755 TCFKQSLV 762
>XP_005272296
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   STCFKR 6
           STCF+R
Sbjct: 847 STCFER 852
>XP_006717400
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   STCFKR 6
           STCF+R
Sbjct: 847 STCFER 852
>XP_005272295
          Length = 961

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   STCFKR 6
           STCF+R
Sbjct: 857 STCFER 862
>XP_006717399
          Length = 1002

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   STCFKR 6
           STCF+R
Sbjct: 956 STCFER 961
>XP_005272294
          Length = 1060

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   STCFKR 6
           STCF+R
Sbjct: 956 STCFER 961
>XP_005265484
          Length = 1626

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 2   TCFKR 6
           TCFKR
Sbjct: 753 TCFKR 757
>XP_005264213
          Length = 477

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 2  TCFKR 6
          TCFKR
Sbjct: 54 TCFKR 58
>NP_787054
          Length = 163

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  TCFKRTT 8
          TC++RT+
Sbjct: 69 TCYRRTS 75
>NP_115510
          Length = 1663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    STCFKRTT 8
            S C+KR T
Sbjct: 1535 SPCYKRVT 1542
>NP_689418
          Length = 839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   STCFKRTTV 9
           ++CFKR  V
Sbjct: 549 TSCFKRQLV 557
>NP_003817
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   TCFKRT 7
           TC+K+T
Sbjct: 192 TCYKKT 197
>NP_002967
          Length = 1682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   CFKRTTV 9
           C +RTT+
Sbjct: 106 CIRRTTI 112
>NP_003301
          Length = 387

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  STCFKRTT 8
          +TC+ RT+
Sbjct: 81 TTCYNRTS 88
>XP_006712745
          Length = 1682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   CFKRTTV 9
           C +RTT+
Sbjct: 106 CIRRTTI 112
>XP_006712744
          Length = 1682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   CFKRTTV 9
           C +RTT+
Sbjct: 106 CIRRTTI 112
>XP_006712743
          Length = 1682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   CFKRTTV 9
           C +RTT+
Sbjct: 106 CIRRTTI 112
>XP_005273217
          Length = 1141

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    CFKRTTV 9
            CF +TTV
Sbjct: 1133 CFPQTTV 1139
>NP_149040
          Length = 475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   STCFKRTTV 9
           S CF+ TT+
Sbjct: 342 SRCFRDTTM 350
>NP_114168
          Length = 159

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  STCFKRTTV 9
          +TC++ TTV
Sbjct: 16 TTCWQPTTV 24
>NP_061947
          Length = 685

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   STCFKRTT 8
           S CF R T
Sbjct: 487 SPCFNRAT 494
>NP_001124162
          Length = 789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  STCFKRTT 8
          ++CF+R T
Sbjct: 9  ASCFRRLT 16
>NP_057004
          Length = 84

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  CFKRTTV 9
          C+K TTV
Sbjct: 40 CYKITTV 46
>NP_001092806
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  CFKRTTV 9
          C++RT+V
Sbjct: 53 CYERTSV 59
>NP_004676
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   STCFKRTTV 9
           S CFK  T+
Sbjct: 567 SLCFKEQTL 575
>NP_940923
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  CFKRTTV 9
          C++RT+V
Sbjct: 53 CYERTSV 59
>NP_001264260
          Length = 160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   TCFKRTTV 9
           TC+  TTV
Sbjct: 119 TCYHPTTV 126
>XP_006719955
          Length = 415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   STCFKRTTV 9
           S CFK  T+
Sbjct: 361 SLCFKEQTL 369
>XP_006719444
          Length = 236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  CFKRTTV 9
          C++RT+V
Sbjct: 53 CYERTSV 59
>XP_006719124
          Length = 1047

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   TCFKRT 7
           TCF+R+
Sbjct: 467 TCFRRS 472
>XP_005253405
          Length = 1463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   TCFKRT 7
           TCF+R+
Sbjct: 467 TCFRRS 472
>XP_005247497
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1  STCFKRT 7
          S CF RT
Sbjct: 93 SICFNRT 99
>NP_001021
          Length = 84

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  CFKRTTV 9
          C+K TTV
Sbjct: 40 CYKITTV 46
>NP_001078889
          Length = 271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   STCFKRT 7
           S CF RT
Sbjct: 105 SICFNRT 111
>NP_777601
          Length = 1453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   TCFKRT 7
           TCF+R+
Sbjct: 457 TCFRRS 462
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.125    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 584,644
Number of extensions: 790
Number of successful extensions: 76
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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