Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              18    1135
NP_653080                                                              18    1135
XP_005267292                                                           18    1135
XP_005267291                                                           18    1135
XP_005267290                                                           18    1135
NP_775897                                                              18    1935
NP_001159821                                                           18    1935
NP_001159820                                                           18    1935
NP_001159819                                                           18    1935
XP_006721897                                                           18    1935
XP_006721896                                                           18    1935
NP_055565                                                              16    7355
NP_001139487                                                           16    7355
NP_005426                                                              15    9605
NP_001003702                                                           15    9605
XP_006726519                                                           15    9605
XP_006723226                                                           15    9605
XP_006716191                                                           15    9605
XP_006716190                                                           15    9605
>NP_005091
          Length = 1782

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    STAVGQARS 9
            STAVGQA S
Sbjct: 1620 STAVGQAHS 1628
>NP_653080
          Length = 1684

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    STAVGQARS 9
            STAVGQA S
Sbjct: 1522 STAVGQAHS 1530
>XP_005267292
          Length = 1677

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    STAVGQARS 9
            STAVGQA S
Sbjct: 1515 STAVGQAHS 1523
>XP_005267291
          Length = 1684

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    STAVGQARS 9
            STAVGQA S
Sbjct: 1522 STAVGQAHS 1530
>XP_005267290
          Length = 1782

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    STAVGQARS 9
            STAVGQA S
Sbjct: 1620 STAVGQAHS 1628
>NP_775897
          Length = 606

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2  TAVGQARS 9
          TA+GQARS
Sbjct: 6  TALGQARS 13
>NP_001159821
          Length = 606

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2  TAVGQARS 9
          TA+GQARS
Sbjct: 6  TALGQARS 13
>NP_001159820
          Length = 606

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2  TAVGQARS 9
          TA+GQARS
Sbjct: 6  TALGQARS 13
>NP_001159819
          Length = 606

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2  TAVGQARS 9
          TA+GQARS
Sbjct: 6  TALGQARS 13
>XP_006721897
          Length = 630

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2  TAVGQARS 9
          TA+GQARS
Sbjct: 6  TALGQARS 13
>XP_006721896
          Length = 630

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2  TAVGQARS 9
          TA+GQARS
Sbjct: 6  TALGQARS 13
>NP_055565
          Length = 846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TAVGQAR 8
           TAVGQ R
Sbjct: 469 TAVGQTR 475
>NP_001139487
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TAVGQAR 8
           TAVGQ R
Sbjct: 469 TAVGQTR 475
>NP_005426
          Length = 1597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AVGQARS 9
           AVG+ARS
Sbjct: 389 AVGRARS 395
>NP_001003702
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AVGQARS 9
           AVG+ARS
Sbjct: 389 AVGRARS 395
>XP_006726519
          Length = 1493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AVGQARS 9
           AVG+ARS
Sbjct: 370 AVGRARS 376
>XP_006723226
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AVGQAR 8
           AVGQAR
Sbjct: 316 AVGQAR 321
>XP_006716191
          Length = 1543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AVGQARS 9
           AVG+ARS
Sbjct: 389 AVGRARS 395
>XP_006716190
          Length = 1597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AVGQARS 9
           AVG+ARS
Sbjct: 389 AVGRARS 395
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.104    0.245 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 307,455
Number of extensions: 132
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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