Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1135
XP_005262424                                                           18    1135
NP_065702                                                              18    1482
XP_005267947                                                           18    1482
XP_006720274                                                           18    1482
XP_005264494                                                           18    1482
XP_005264493                                                           18    1482
NP_067078                                                              18    1482
NP_001124320                                                           17    3301
NP_004901                                                              17    3301
NP_001243372                                                           17    4312
NP_001243371                                                           17    4312
NP_660282                                                              17    4312
XP_006721069                                                           17    4312
NP_006452                                                              16    5631
NP_006826                                                              16    5631
NP_998761                                                              16    5631
NP_001363                                                              16    5631
XP_006721528                                                           16    5631
NP_004653                                                              16    5631
NP_055918                                                              16    7355
NP_005303                                                              16    7355
NP_941372                                                              16    7355
XP_005272252                                                           16    7355
XP_006717137                                                           16    7355
XP_006717136                                                           16    7355
XP_005272248                                                           16    7355
XP_006717135                                                           16    7355
XP_006717134                                                           16    7355
XP_006717133                                                           16    7355
XP_006717132                                                           16    7355
XP_005272243                                                           16    7355
XP_005272242                                                           16    7355
XP_006717131                                                           16    7355
XP_006717130                                                           16    7355
NP_009036                                                              16    7355
NP_878908                                                              15    9605
NP_001005853                                                           15    9605
NP_877398                                                              15    9605
NP_056007                                                              15    9605
NP_055969                                                              15    9605
NP_006043                                                              15    9605
XP_006726924                                                           15    9605
XP_005260968                                                           15    9605
XP_005260966                                                           15    9605
XP_005260738                                                           15    9605
XP_006723618                                                           15    9605
XP_005247061                                                           15    9605
NP_775486                                                              15    9605
>NP_722576
          Length = 3080

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STAAPVDFV 9
           STAAPVD V
Sbjct: 475 STAAPVDSV 483
>XP_005262424
          Length = 2875

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STAAPVDFV 9
           STAAPVD V
Sbjct: 270 STAAPVDSV 278
>NP_065702
          Length = 418

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STAAPVDFV 9
           ST +P+DFV
Sbjct: 105 STESPIDFV 113
>XP_005267947
          Length = 247

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STAAPVDFV 9
           ST +P+DFV
Sbjct: 107 STESPIDFV 115
>XP_006720274
          Length = 320

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  STAAPVDFV 9
          ST +P+DFV
Sbjct: 7  STESPIDFV 15
>XP_005264494
          Length = 320

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  STAAPVDFV 9
          ST +P+DFV
Sbjct: 7  STESPIDFV 15
>XP_005264493
          Length = 352

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  STAAPVDFV 9
          ST +P+DFV
Sbjct: 39 STESPIDFV 47
>NP_067078
          Length = 420

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STAAPVDFV 9
           ST +P+DFV
Sbjct: 107 STESPIDFV 115
>NP_001124320
          Length = 1243

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AAPVDFV 9
            AAPVDF+
Sbjct: 1194 AAPVDFL 1200
>NP_004901
          Length = 1244

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AAPVDFV 9
            AAPVDF+
Sbjct: 1195 AAPVDFL 1201
>NP_001243372
          Length = 299

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  STAAPVD 7
          +TAAPVD
Sbjct: 54 TTAAPVD 60
>NP_001243371
          Length = 394

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  STAAPVD 7
          +TAAPVD
Sbjct: 54 TTAAPVD 60
>NP_660282
          Length = 340

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  STAAPVD 7
          +TAAPVD
Sbjct: 54 TTAAPVD 60
>XP_006721069
          Length = 340

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  STAAPVD 7
          +TAAPVD
Sbjct: 54 TTAAPVD 60
>NP_006452
          Length = 1193

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  STAAPVDFV 9
          + ++PVDFV
Sbjct: 63 NNSSPVDFV 71
>NP_006826
          Length = 377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TAAPVDFV 9
           TA P+DF+
Sbjct: 144 TATPLDFL 151
>NP_998761
          Length = 517

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   APVDFV 9
           APVDF+
Sbjct: 403 APVDFI 408
>NP_001363
          Length = 4486

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    TAAPVDFV 9
            TA+PV+F+
Sbjct: 3786 TASPVEFL 3793
>XP_006721528
          Length = 3869

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    TAAPVDFV 9
            TA+PV+F+
Sbjct: 3786 TASPVEFL 3793
>NP_004653
          Length = 798

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TAAPVDFV 9
           TA+PV+F+
Sbjct: 98  TASPVEFL 105
>NP_055918
          Length = 1925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    STAAPVDF 8
            + +APVDF
Sbjct: 1132 NASAPVDF 1139
>NP_005303
          Length = 1077

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TAAPVDFV 9
           ++APV+FV
Sbjct: 518 SSAPVEFV 525
>NP_941372
          Length = 1095

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TAAPVDFV 9
           ++APV+FV
Sbjct: 536 SSAPVEFV 543
>XP_005272252
          Length = 1094

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TAAPVDFV 9
           ++APV+FV
Sbjct: 535 SSAPVEFV 542
>XP_006717137
          Length = 1100

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TAAPVDFV 9
           ++APV+FV
Sbjct: 541 SSAPVEFV 548
>XP_006717136
          Length = 1200

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TAAPVDFV 9
           ++APV+FV
Sbjct: 503 SSAPVEFV 510
>XP_005272248
          Length = 1226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TAAPVDFV 9
           ++APV+FV
Sbjct: 497 SSAPVEFV 504
>XP_006717135
          Length = 1232

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TAAPVDFV 9
           ++APV+FV
Sbjct: 503 SSAPVEFV 510
>XP_006717134
          Length = 1238

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TAAPVDFV 9
           ++APV+FV
Sbjct: 541 SSAPVEFV 548
>XP_006717133
          Length = 1239

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TAAPVDFV 9
           ++APV+FV
Sbjct: 541 SSAPVEFV 548
>XP_006717132
          Length = 1254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TAAPVDFV 9
           ++APV+FV
Sbjct: 541 SSAPVEFV 548
>XP_005272243
          Length = 1264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TAAPVDFV 9
           ++APV+FV
Sbjct: 535 SSAPVEFV 542
>XP_005272242
          Length = 1265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TAAPVDFV 9
           ++APV+FV
Sbjct: 536 SSAPVEFV 543
>XP_006717131
          Length = 1269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TAAPVDFV 9
           ++APV+FV
Sbjct: 541 SSAPVEFV 548
>XP_006717130
          Length = 1270

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TAAPVDFV 9
           ++APV+FV
Sbjct: 541 SSAPVEFV 548
>NP_009036
          Length = 253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TAAPVDFV 9
          T AP+DF+
Sbjct: 26 TLAPLDFL 33
>NP_878908
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   STAAPV 6
           STAAPV
Sbjct: 326 STAAPV 331
>NP_001005853
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STAAPVDFV 9
           STA  VDF+
Sbjct: 193 STAELVDFI 201
>NP_877398
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TAAPVDFV 9
           T +PV+FV
Sbjct: 580 TKSPVEFV 587
>NP_056007
          Length = 1216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TAAPVDFV 9
           T +PV+FV
Sbjct: 580 TKSPVEFV 587
>NP_055969
          Length = 234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  AAPVDF 8
          +APVDF
Sbjct: 88 SAPVDF 93
>NP_006043
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   TAAPVDF 8
           T +PVDF
Sbjct: 151 TPSPVDF 157
>XP_006726924
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   STAAPV 6
           STAAPV
Sbjct: 312 STAAPV 317
>XP_005260968
          Length = 172

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  TAAPVDF 8
          T +PVDF
Sbjct: 26 TPSPVDF 32
>XP_005260966
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   TAAPVDF 8
           T +PVDF
Sbjct: 124 TPSPVDF 130
>XP_005260738
          Length = 877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TAAPVDFV 9
           T +PV+FV
Sbjct: 580 TKSPVEFV 587
>XP_006723618
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TAAPVDFV 9
           T +PV+FV
Sbjct: 580 TKSPVEFV 587
>XP_005247061
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STAAPVDFV 9
           STA  VDF+
Sbjct: 193 STAELVDFI 201
>NP_775486
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   STAAPVDFV 9
           STA  VDF+
Sbjct: 193 STAELVDFI 201
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.126    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 580,427
Number of extensions: 407
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package