Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              19     869
NP_001120972                                                           19     869
XP_006716054                                                           19     869
XP_006716053                                                           19     869
XP_006716052                                                           19     869
XP_006716051                                                           19     869
NP_073594                                                              16    5631
XP_006713796                                                           16    5631
XP_006713795                                                           16    5631
XP_005247771                                                           16    5631
XP_005247770                                                           16    5631
XP_005247769                                                           16    5631
XP_005247768                                                           16    5631
XP_006713794                                                           16    5631
XP_005247767                                                           16    5631
NP_079052                                                              16    7355
NP_001263347                                                           16    7355
NP_055681                                                              16    7355
NP_570843                                                              16    7355
NP_001128529                                                           16    7355
NP_116321                                                              16    7355
XP_005258102                                                           16    7355
XP_005254732                                                           16    7355
XP_005254731                                                           16    7355
XP_006720754                                                           16    7355
XP_005254729                                                           16    7355
XP_005254730                                                           16    7355
XP_005254728                                                           16    7355
XP_005254727                                                           16    7355
XP_005266194                                                           16    7355
XP_005266191                                                           16    7355
XP_005266190                                                           16    7355
XP_005266189                                                           16    7355
NP_005091                                                              15    9605
NP_653080                                                              15    9605
NP_060959                                                              15    9605
XP_005267292                                                           15    9605
XP_005267291                                                           15    9605
XP_005267290                                                           15    9605
XP_005264475                                                           15    9605
XP_005245394                                                           15    9605
XP_005245393                                                           15    9605
XP_006711515                                                           15    9605
XP_006711514                                                           15    9605
XP_006711513                                                           15    9605
>NP_000236
          Length = 1390

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSTTEMVSN 9
           S TTEMVSN
Sbjct: 990 SPTTEMVSN 998
>NP_001120972
          Length = 1408

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSTTEMVSN 9
            S TTEMVSN
Sbjct: 1008 SPTTEMVSN 1016
>XP_006716054
          Length = 960

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSTTEMVSN 9
           S TTEMVSN
Sbjct: 560 SPTTEMVSN 568
>XP_006716053
          Length = 960

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSTTEMVSN 9
           S TTEMVSN
Sbjct: 560 SPTTEMVSN 568
>XP_006716052
          Length = 1409

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSTTEMVSN 9
            S TTEMVSN
Sbjct: 1009 SPTTEMVSN 1017
>XP_006716051
          Length = 1427

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSTTEMVSN 9
            S TTEMVSN
Sbjct: 1027 SPTTEMVSN 1035
>NP_073594
          Length = 912

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SSTTEMVSN 9
           ++TT++VSN
Sbjct: 764 AATTQLVSN 772
>XP_006713796
          Length = 651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SSTTEMVSN 9
           ++TT++VSN
Sbjct: 503 AATTQLVSN 511
>XP_006713795
          Length = 753

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SSTTEMVSN 9
           ++TT++VSN
Sbjct: 605 AATTQLVSN 613
>XP_005247771
          Length = 753

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SSTTEMVSN 9
           ++TT++VSN
Sbjct: 605 AATTQLVSN 613
>XP_005247770
          Length = 753

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SSTTEMVSN 9
           ++TT++VSN
Sbjct: 605 AATTQLVSN 613
>XP_005247769
          Length = 753

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SSTTEMVSN 9
           ++TT++VSN
Sbjct: 605 AATTQLVSN 613
>XP_005247768
          Length = 794

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SSTTEMVSN 9
           ++TT++VSN
Sbjct: 646 AATTQLVSN 654
>XP_006713794
          Length = 810

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SSTTEMVSN 9
           ++TT++VSN
Sbjct: 662 AATTQLVSN 670
>XP_005247767
          Length = 953

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SSTTEMVSN 9
           ++TT++VSN
Sbjct: 805 AATTQLVSN 813
>NP_079052
          Length = 1746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SSTTEMVSN 9
           S +TE++SN
Sbjct: 212 SGSTEVISN 220
>NP_001263347
          Length = 2334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSTTEMVSN 9
           S  +EMVSN
Sbjct: 911 SGASEMVSN 919
>NP_055681
          Length = 2357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSTTEMVSN 9
           S  +EMVSN
Sbjct: 911 SGASEMVSN 919
>NP_570843
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSTTEMVS 8
           SSTTE+ S
Sbjct: 503 SSTTELTS 510
>NP_001128529
          Length = 587

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSTTEMVS 8
           SSTTE+ S
Sbjct: 509 SSTTELTS 516
>NP_116321
          Length = 637

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   STTEMVSN 9
           STT ++SN
Sbjct: 205 STTSLISN 212
>XP_005258102
          Length = 607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   STTEMVSN 9
           STT ++SN
Sbjct: 175 STTSLISN 182
>XP_005254732
          Length = 1746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SSTTEMVSN 9
           S +TE++SN
Sbjct: 212 SGSTEVISN 220
>XP_005254731
          Length = 1746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SSTTEMVSN 9
           S +TE++SN
Sbjct: 212 SGSTEVISN 220
>XP_006720754
          Length = 1746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SSTTEMVSN 9
           S +TE++SN
Sbjct: 212 SGSTEVISN 220
>XP_005254729
          Length = 1746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SSTTEMVSN 9
           S +TE++SN
Sbjct: 212 SGSTEVISN 220
>XP_005254730
          Length = 1746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SSTTEMVSN 9
           S +TE++SN
Sbjct: 212 SGSTEVISN 220
>XP_005254728
          Length = 1746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SSTTEMVSN 9
           S +TE++SN
Sbjct: 212 SGSTEVISN 220
>XP_005254727
          Length = 1746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SSTTEMVSN 9
           S +TE++SN
Sbjct: 212 SGSTEVISN 220
>XP_005266194
          Length = 2379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSTTEMVSN 9
           S  +EMVSN
Sbjct: 911 SGASEMVSN 919
>XP_005266191
          Length = 2379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSTTEMVSN 9
           S  +EMVSN
Sbjct: 911 SGASEMVSN 919
>XP_005266190
          Length = 2485

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSTTEMVSN 9
            S  +EMVSN
Sbjct: 1059 SGASEMVSN 1067
>XP_005266189
          Length = 2505

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSTTEMVSN 9
            S  +EMVSN
Sbjct: 1059 SGASEMVSN 1067
>NP_005091
          Length = 1782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TTEMVS 8
            TTEMVS
Sbjct: 999  TTEMVS 1004
>NP_653080
          Length = 1684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TTEMVS 8
           TTEMVS
Sbjct: 901 TTEMVS 906
>NP_060959
          Length = 2964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SSTTEMV 7
           SSTTE++
Sbjct: 586 SSTTELI 592
>XP_005267292
          Length = 1677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TTEMVS 8
           TTEMVS
Sbjct: 894 TTEMVS 899
>XP_005267291
          Length = 1684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TTEMVS 8
           TTEMVS
Sbjct: 901 TTEMVS 906
>XP_005267290
          Length = 1782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TTEMVS 8
            TTEMVS
Sbjct: 999  TTEMVS 1004
>XP_005264475
          Length = 2027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSTTEMVSN 9
            S  TE+VSN
Sbjct: 1937 SLNTELVSN 1945
>XP_005245394
          Length = 1741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SSTTEMV 7
           SSTTE++
Sbjct: 586 SSTTELI 592
>XP_005245393
          Length = 2663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SSTTEMV 7
           SSTTE++
Sbjct: 586 SSTTELI 592
>XP_006711515
          Length = 2904

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SSTTEMV 7
           SSTTE++
Sbjct: 586 SSTTELI 592
>XP_006711514
          Length = 2964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SSTTEMV 7
           SSTTE++
Sbjct: 586 SSTTELI 592
>XP_006711513
          Length = 2964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SSTTEMV 7
           SSTTE++
Sbjct: 586 SSTTELI 592
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.275   0.0865    0.184 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 266,943
Number of extensions: 233
Number of successful extensions: 45
Number of sequences better than 10000.0: 45
Number of HSP's gapped: 45
Number of HSP's successfully gapped: 45
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.6 bits)
S2: 28 (15.4 bits)

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