Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_689621                                                              18    1935
NP_001092741                                                           18    1935
XP_005248493                                                           18    1935
XP_005248492                                                           18    1935
NP_001185761                                                           17    3301
NP_001185763                                                           17    3301
NP_055459                                                              17    3301
XP_006726410                                                           17    3301
XP_006711719                                                           17    3301
XP_006711718                                                           17    3301
XP_006711717                                                           17    3301
XP_006711716                                                           17    3301
XP_006711715                                                           17    3301
XP_006711714                                                           17    3301
XP_006711713                                                           17    3301
XP_006711712                                                           17    3301
XP_006711711                                                           17    3301
XP_006711710                                                           17    3301
XP_006711709                                                           17    3301
XP_005277503                                                           17    3301
XP_005273038                                                           17    3301
XP_006711708                                                           17    3301
XP_005277500                                                           17    3301
XP_006711707                                                           17    3301
XP_005277499                                                           17    3301
XP_006711706                                                           17    3301
XP_006711705                                                           17    3301
XP_006711164                                                           17    3301
XP_006710143                                                           17    3301
XP_006710142                                                           17    3301
XP_006710141                                                           17    3301
XP_006719747                                                           16    5631
XP_005269273                                                           16    5631
NP_612398                                                              16    7355
NP_848599                                                              16    7355
XP_005262730                                                           16    7355
XP_005262729                                                           16    7355
XP_006713081                                                           16    7355
NP_114096                                                              16    7355
NP_001139317                                                           15    9605
NP_598334                                                              15    9605
NP_002932                                                              15    9605
NP_079255                                                              15    9605
NP_477352                                                              15    9605
NP_056538                                                              15    9605
NP_001242938                                                           15    9605
NP_001242937                                                           15    9605
NP_001242936                                                           15    9605
NP_001072982                                                           15    9605
NP_001106203                                                           15    9605
NP_001275585                                                           15    9605
XP_005261692                                                           15    9605
XP_005261691                                                           15    9605
XP_005255337                                                           15    9605
XP_005255336                                                           15    9605
XP_005255335                                                           15    9605
XP_005255334                                                           15    9605
XP_005268373                                                           15    9605
XP_005268372                                                           15    9605
XP_005268371                                                           15    9605
XP_006720031                                                           15    9605
XP_005268370                                                           15    9605
XP_006720030                                                           15    9605
XP_005268369                                                           15    9605
XP_006720029                                                           15    9605
XP_005268367                                                           15    9605
XP_005268366                                                           15    9605
XP_005268365                                                           15    9605
XP_005268364                                                           15    9605
XP_005250453                                                           15    9605
XP_006713341                                                           15    9605
XP_006713340                                                           15    9605
XP_006713339                                                           15    9605
>NP_689621
          Length = 550

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSTSASRGL 9
           SSTSASR L
Sbjct: 522 SSTSASRSL 530
>NP_001092741
          Length = 575

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSTSASRGL 9
           SSTSASR L
Sbjct: 547 SSTSASRSL 555
>XP_005248493
          Length = 547

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSTSASRGL 9
           SSTSASR L
Sbjct: 519 SSTSASRSL 527
>XP_005248492
          Length = 548

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSTSASRGL 9
           SSTSASR L
Sbjct: 520 SSTSASRSL 528
>NP_001185761
          Length = 2240

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1615 SSTSASQG 1622
>NP_001185763
          Length = 2362

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1659 SSTSASQG 1666
>NP_055459
          Length = 2346

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1659 SSTSASQG 1666
>XP_006726410
          Length = 2087

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1462 SSTSASQG 1469
>XP_006711719
          Length = 2302

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1615 SSTSASQG 1622
>XP_006711718
          Length = 1436

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SSTSASRG 8
           SSTSAS+G
Sbjct: 666 SSTSASQG 673
>XP_006711717
          Length = 2385

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1615 SSTSASQG 1622
>XP_006711716
          Length = 2411

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1724 SSTSASQG 1731
>XP_006711715
          Length = 2428

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1658 SSTSASQG 1665
>XP_006711714
          Length = 2429

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1659 SSTSASQG 1666
>XP_006711713
          Length = 2432

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1662 SSTSASQG 1669
>XP_006711712
          Length = 2473

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1822 SSTSASQG 1829
>XP_006711711
          Length = 2482

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1712 SSTSASQG 1719
>XP_006711710
          Length = 2494

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1724 SSTSASQG 1731
>XP_006711709
          Length = 2495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1725 SSTSASQG 1732
>XP_005277503
          Length = 2498

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1822 SSTSASQG 1829
>XP_005273038
          Length = 2509

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1822 SSTSASQG 1829
>XP_006711708
          Length = 2512

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1822 SSTSASQG 1829
>XP_005277500
          Length = 2525

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1822 SSTSASQG 1829
>XP_006711707
          Length = 2553

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1822 SSTSASQG 1829
>XP_005277499
          Length = 2561

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1822 SSTSASQG 1829
>XP_006711706
          Length = 2591

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1821 SSTSASQG 1828
>XP_006711705
          Length = 2592

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1822 SSTSASQG 1829
>XP_006711164
          Length = 2087

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSTSASRG 8
            SSTSAS+G
Sbjct: 1462 SSTSASQG 1469
>XP_006710143
          Length = 562

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SSTSASRG 8
           SSTSAS+G
Sbjct: 501 SSTSASQG 508
>XP_006710142
          Length = 671

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SSTSASRG 8
           SSTSAS+G
Sbjct: 610 SSTSASQG 617
>XP_006710141
          Length = 672

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SSTSASRG 8
           SSTSAS+G
Sbjct: 611 SSTSASQG 618
>XP_006719747
          Length = 230

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   STSASRGL 9
           +TSA+RGL
Sbjct: 102 ATSAARGL 109
>XP_005269273
          Length = 309

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   STSASRGL 9
           +TSA+RGL
Sbjct: 102 ATSAARGL 109
>NP_612398
          Length = 563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSTSASRGL 9
           S +SASRG+
Sbjct: 200 SPSSASRGM 208
>NP_848599
          Length = 3092

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    STSASRG 8
            STSA+RG
Sbjct: 1057 STSAARG 1063
>XP_005262730
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSTSASRGL 9
           S +SASRG+
Sbjct: 200 SPSSASRGM 208
>XP_005262729
          Length = 563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSTSASRGL 9
           S +SASRG+
Sbjct: 200 SPSSASRGM 208
>XP_006713081
          Length = 3964

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    STSASRG 8
            STSA+RG
Sbjct: 1080 STSAARG 1086
>NP_114096
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SSTSASRG 8
          +STS SRG
Sbjct: 48 TSTSTSRG 55
>NP_001139317
          Length = 1551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSTSASRG 8
            SSTS S+G
Sbjct: 1057 SSTSGSQG 1064
>NP_598334
          Length = 1606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSTSASRG 8
            SSTS S+G
Sbjct: 1112 SSTSGSQG 1119
>NP_002932
          Length = 1651

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSTSASRG 8
            SSTS S+G
Sbjct: 1157 SSTSGSQG 1164
>NP_079255
          Length = 1123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSTSASRG 8
           +STS SRG
Sbjct: 940 TSTSPSRG 947
>NP_477352
          Length = 2102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SSTSASRG 8
          S +SASRG
Sbjct: 22 SGSSASRG 29
>NP_056538
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  STSASRGL 9
          STSA +GL
Sbjct: 87 STSAPKGL 94
>NP_001242938
          Length = 720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  STSASRGL 9
          STSA +GL
Sbjct: 87 STSAPKGL 94
>NP_001242937
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  STSASRGL 9
          STSA +GL
Sbjct: 87 STSAPKGL 94
>NP_001242936
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  STSASRGL 9
          STSA +GL
Sbjct: 87 STSAPKGL 94
>NP_001072982
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSTSASRG 8
            SSTS S+G
Sbjct: 1003 SSTSLSKG 1010
>NP_001106203
          Length = 1125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSTSASRG 8
           +STS SRG
Sbjct: 942 TSTSPSRG 949
>NP_001275585
          Length = 1104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSTSASRG 8
            SSTS S+G
Sbjct: 1003 SSTSLSKG 1010
>XP_005261692
          Length = 1854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SSTSASRG 8
          S +SASRG
Sbjct: 50 SGSSASRG 57
>XP_005261691
          Length = 2099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SSTSASRG 8
          S +SASRG
Sbjct: 50 SGSSASRG 57
>XP_005255337
          Length = 1104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSTSASRG 8
            SSTS S+G
Sbjct: 1003 SSTSLSKG 1010
>XP_005255336
          Length = 1112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSTSASRG 8
           SSTS S+G
Sbjct: 954 SSTSLSKG 961
>XP_005255335
          Length = 1161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSTSASRG 8
            SSTS S+G
Sbjct: 1003 SSTSLSKG 1010
>XP_005255334
          Length = 1161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSTSASRG 8
            SSTS S+G
Sbjct: 1003 SSTSLSKG 1010
>XP_005268373
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSTSASRG 8
           +STS SRG
Sbjct: 940 TSTSPSRG 947
>XP_005268372
          Length = 1043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSTSASRG 8
            +STS SRG
Sbjct: 999  TSTSPSRG 1006
>XP_005268371
          Length = 1067

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSTSASRG 8
           +STS SRG
Sbjct: 946 TSTSPSRG 953
>XP_006720031
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSTSASRG 8
           +STS SRG
Sbjct: 872 TSTSPSRG 879
>XP_005268370
          Length = 1112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSTSASRG 8
           +STS SRG
Sbjct: 904 TSTSPSRG 911
>XP_006720030
          Length = 1128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSTSASRG 8
           +STS SRG
Sbjct: 920 TSTSPSRG 927
>XP_005268369
          Length = 1132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSTSASRG 8
           +STS SRG
Sbjct: 924 TSTSPSRG 931
>XP_006720029
          Length = 1150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSTSASRG 8
           +STS SRG
Sbjct: 942 TSTSPSRG 949
>XP_005268367
          Length = 1154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSTSASRG 8
           +STS SRG
Sbjct: 946 TSTSPSRG 953
>XP_005268366
          Length = 1180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSTSASRG 8
           +STS SRG
Sbjct: 972 TSTSPSRG 979
>XP_005268365
          Length = 1182

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSTSASRG 8
            +STS SRG
Sbjct: 999  TSTSPSRG 1006
>XP_005268364
          Length = 1207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSTSASRG 8
            +STS SRG
Sbjct: 999  TSTSPSRG 1006
>XP_005250453
          Length = 720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  STSASRGL 9
          STSA +GL
Sbjct: 87 STSAPKGL 94
>XP_006713341
          Length = 1600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSTSASRG 8
            SSTS S+G
Sbjct: 1106 SSTSGSQG 1113
>XP_006713340
          Length = 1615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSTSASRG 8
            SSTS S+G
Sbjct: 1121 SSTSGSQG 1128
>XP_006713339
          Length = 1616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSTSASRG 8
            SSTS S+G
Sbjct: 1122 SSTSGSQG 1129
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.287   0.0983    0.221 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 291,547
Number of extensions: 306
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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