Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     869
NP_001185763                                                           19     869
NP_055459                                                              19     869
XP_006726410                                                           19     869
XP_006711719                                                           19     869
XP_006711718                                                           19     869
XP_006711717                                                           19     869
XP_006711716                                                           19     869
XP_006711715                                                           19     869
XP_006711714                                                           19     869
XP_006711713                                                           19     869
XP_006711712                                                           19     869
XP_006711711                                                           19     869
XP_006711710                                                           19     869
XP_006711709                                                           19     869
XP_005277503                                                           19     869
XP_005273038                                                           19     869
XP_006711708                                                           19     869
XP_005277500                                                           19     869
XP_006711707                                                           19     869
XP_005277499                                                           19     869
XP_006711706                                                           19     869
XP_006711705                                                           19     869
XP_006711164                                                           19     869
XP_006710140                                                           19     869
NP_004733                                                              17    3301
NP_001028229                                                           17    3301
NP_056335                                                              17    3301
NP_001265092                                                           17    3301
NP_001265091                                                           17    3301
NP_005725                                                              17    3301
NP_001041665                                                           17    3301
NP_872393                                                              17    3301
XP_006718183                                                           17    3301
XP_005252786                                                           17    3301
XP_005265631                                                           17    3301
XP_006713477                                                           17    3301
XP_006713476                                                           17    3301
XP_005265628                                                           17    3301
XP_005265627                                                           17    3301
XP_006713475                                                           17    3301
XP_006713474                                                           17    3301
XP_005265625                                                           17    3301
XP_006713473                                                           17    3301
XP_005265623                                                           17    3301
XP_005265622                                                           17    3301
XP_005265621                                                           17    3301
XP_005265620                                                           17    3301
XP_006713472                                                           17    3301
XP_006713471                                                           17    3301
XP_006713470                                                           17    3301
XP_006712515                                                           17    3301
XP_006712514                                                           17    3301
XP_006712513                                                           17    3301
XP_006712512                                                           17    3301
XP_006712511                                                           17    3301
XP_006712510                                                           17    3301
XP_006712509                                                           17    3301
XP_005246533                                                           17    3301
XP_006712508                                                           17    3301
NP_115893                                                              17    3301
NP_055824                                                              17    4312
NP_061897                                                              17    4312
XP_006723740                                                           17    4312
XP_005264775                                                           17    4312
XP_005264436                                                           17    4312
XP_006712098                                                           17    4312
XP_006712097                                                           17    4312
XP_006710329                                                           17    4312
NP_115785                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1657 ASTATLLSN 1665
>NP_001185763
          Length = 2362

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1763 ASTATLLSN 1771
>NP_055459
          Length = 2346

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1763 ASTATLLSN 1771
>XP_006726410
          Length = 2087

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1504 ASTATLLSN 1512
>XP_006711719
          Length = 2302

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1719 ASTATLLSN 1727
>XP_006711718
          Length = 1436

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SSTATLLSN 9
           +STATLLSN
Sbjct: 770 ASTATLLSN 778
>XP_006711717
          Length = 2385

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1719 ASTATLLSN 1727
>XP_006711716
          Length = 2411

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1828 ASTATLLSN 1836
>XP_006711715
          Length = 2428

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1762 ASTATLLSN 1770
>XP_006711714
          Length = 2429

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1763 ASTATLLSN 1771
>XP_006711713
          Length = 2432

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1766 ASTATLLSN 1774
>XP_006711712
          Length = 2473

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1926 ASTATLLSN 1934
>XP_006711711
          Length = 2482

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1816 ASTATLLSN 1824
>XP_006711710
          Length = 2494

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1828 ASTATLLSN 1836
>XP_006711709
          Length = 2495

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1829 ASTATLLSN 1837
>XP_005277503
          Length = 2498

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1926 ASTATLLSN 1934
>XP_005273038
          Length = 2509

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1926 ASTATLLSN 1934
>XP_006711708
          Length = 2512

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1926 ASTATLLSN 1934
>XP_005277500
          Length = 2525

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1926 ASTATLLSN 1934
>XP_006711707
          Length = 2553

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1926 ASTATLLSN 1934
>XP_005277499
          Length = 2561

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1926 ASTATLLSN 1934
>XP_006711706
          Length = 2591

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1925 ASTATLLSN 1933
>XP_006711705
          Length = 2592

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1926 ASTATLLSN 1934
>XP_006711164
          Length = 2087

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSTATLLSN 9
            +STATLLSN
Sbjct: 1504 ASTATLLSN 1512
>XP_006710140
          Length = 290

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  SSTATLLSN 9
          +STATLLSN
Sbjct: 16 ASTATLLSN 24
>NP_004733
          Length = 1256

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1096 SSNATLLTN 1104
>NP_001028229
          Length = 1462

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1067 SSNATLLTN 1075
>NP_056335
          Length = 1287

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1095 SSNATLLTN 1103
>NP_001265092
          Length = 1194

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSTATLLSN 9
           SSTATL +N
Sbjct: 573 SSTATLTAN 581
>NP_001265091
          Length = 1194

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSTATLLSN 9
           SSTATL +N
Sbjct: 573 SSTATLTAN 581
>NP_005725
          Length = 1215

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSTATLLSN 9
           SSTATL +N
Sbjct: 573 SSTATLTAN 581
>NP_001041665
          Length = 1194

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSTATLLSN 9
           SSTATL +N
Sbjct: 573 SSTATLTAN 581
>NP_872393
          Length = 3234

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  TATLLSN 9
          TATLLSN
Sbjct: 89 TATLLSN 95
>XP_006718183
          Length = 1215

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSTATLLSN 9
           SSTATL +N
Sbjct: 573 SSTATLTAN 581
>XP_005252786
          Length = 1215

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSTATLLSN 9
           SSTATL +N
Sbjct: 573 SSTATLTAN 581
>XP_005265631
          Length = 1288

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1096 SSNATLLTN 1104
>XP_006713477
          Length = 1290

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1098 SSNATLLTN 1106
>XP_006713476
          Length = 1375

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSTATLLSN 9
           SS ATLL+N
Sbjct: 980 SSNATLLTN 988
>XP_005265628
          Length = 1395

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1000 SSNATLLTN 1008
>XP_005265627
          Length = 1425

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1030 SSNATLLTN 1038
>XP_006713475
          Length = 1463

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1068 SSNATLLTN 1076
>XP_006713474
          Length = 1465

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1070 SSNATLLTN 1078
>XP_005265625
          Length = 1478

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1083 SSNATLLTN 1091
>XP_006713473
          Length = 1479

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1084 SSNATLLTN 1092
>XP_005265623
          Length = 1479

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1084 SSNATLLTN 1092
>XP_005265622
          Length = 1481

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1086 SSNATLLTN 1094
>XP_005265621
          Length = 1491

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1096 SSNATLLTN 1104
>XP_005265620
          Length = 1492

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1097 SSNATLLTN 1105
>XP_006713472
          Length = 1492

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1097 SSNATLLTN 1105
>XP_006713471
          Length = 1492

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1097 SSNATLLTN 1105
>XP_006713470
          Length = 1493

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSTATLLSN 9
            SS ATLL+N
Sbjct: 1098 SSNATLLTN 1106
>XP_006712515
          Length = 3232

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  TATLLSN 9
          TATLLSN
Sbjct: 89 TATLLSN 95
>XP_006712514
          Length = 2496

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  TATLLSN 9
          TATLLSN
Sbjct: 89 TATLLSN 95
>XP_006712513
          Length = 3220

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  TATLLSN 9
          TATLLSN
Sbjct: 89 TATLLSN 95
>XP_006712512
          Length = 3237

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  TATLLSN 9
          TATLLSN
Sbjct: 89 TATLLSN 95
>XP_006712511
          Length = 3256

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  TATLLSN 9
          TATLLSN
Sbjct: 89 TATLLSN 95
>XP_006712510
          Length = 3305

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  TATLLSN 9
          TATLLSN
Sbjct: 89 TATLLSN 95
>XP_006712509
          Length = 3319

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  TATLLSN 9
          TATLLSN
Sbjct: 89 TATLLSN 95
>XP_005246533
          Length = 3323

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  TATLLSN 9
          TATLLSN
Sbjct: 89 TATLLSN 95
>XP_006712508
          Length = 3324

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  TATLLSN 9
          TATLLSN
Sbjct: 89 TATLLSN 95
>NP_115893
          Length = 3258

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  TATLLSN 9
          TATLLSN
Sbjct: 89 TATLLSN 95
>NP_055824
          Length = 1066

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSTATLLSN 9
           + TAT+LSN
Sbjct: 555 TDTATILSN 563
>NP_061897
          Length = 2071

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    STATLLSN 9
            STATLLS+
Sbjct: 1203 STATLLSS 1210
>XP_006723740
          Length = 142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   STATLLSN 9
           STATLLS+
Sbjct: 93  STATLLSS 100
>XP_005264775
          Length = 783

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSTATLLSN 9
           + TAT+LSN
Sbjct: 272 TDTATILSN 280
>XP_005264436
          Length = 1881

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    STATLLSN 9
            STATLLS+
Sbjct: 1203 STATLLSS 1210
>XP_006712098
          Length = 2059

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    STATLLSN 9
            STATLLS+
Sbjct: 1191 STATLLSS 1198
>XP_006712097
          Length = 2070

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    STATLLSN 9
            STATLLS+
Sbjct: 1203 STATLLSS 1210
>XP_006710329
          Length = 142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   STATLLSN 9
           STATLLS+
Sbjct: 93  STATLLSS 100
>NP_115785
          Length = 581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   STATLLSN 9
           S ATLL+N
Sbjct: 535 SAATLLAN 542
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.285   0.0952    0.206 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 242,239
Number of extensions: 254
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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