Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              17    3301
NP_001263689                                                           17    3301
NP_001119584                                                           17    3301
NP_001119586                                                           17    3301
NP_001263625                                                           17    3301
NP_001119590                                                           17    3301
NP_001263690                                                           17    3301
NP_001119585                                                           17    3301
NP_001263624                                                           17    3301
NP_001018121                                                           17    4312
NP_001136113                                                           16    5631
NP_005388                                                              16    5631
NP_001129575                                                           15    9605
NP_733751                                                              15    9605
NP_001273148                                                           15    9605
NP_001123885                                                           15    9605
NP_443139                                                              15    9605
XP_006719284                                                           15    9605
XP_006719283                                                           15    9605
XP_006719282                                                           15    9605
XP_006716142                                                           15    9605
XP_005250088                                                           15    9605
XP_006716141                                                           15    9605
XP_005250085                                                           15    9605
XP_006716140                                                           15    9605
XP_005250084                                                           15    9605
XP_005250083                                                           15    9605
XP_005250082                                                           15    9605
>NP_000537
          Length = 393

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSSVLSQKT 9
           SSSV SQKT
Sbjct: 94  SSSVPSQKT 102
>NP_001263689
          Length = 354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SSSVLSQKT 9
          SSSV SQKT
Sbjct: 55 SSSVPSQKT 63
>NP_001119584
          Length = 393

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSSVLSQKT 9
           SSSV SQKT
Sbjct: 94  SSSVPSQKT 102
>NP_001119586
          Length = 341

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSSVLSQKT 9
           SSSV SQKT
Sbjct: 94  SSSVPSQKT 102
>NP_001263625
          Length = 302

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SSSVLSQKT 9
          SSSV SQKT
Sbjct: 55 SSSVPSQKT 63
>NP_001119590
          Length = 354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SSSVLSQKT 9
          SSSV SQKT
Sbjct: 55 SSSVPSQKT 63
>NP_001263690
          Length = 354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SSSVLSQKT 9
          SSSV SQKT
Sbjct: 55 SSSVPSQKT 63
>NP_001119585
          Length = 346

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSSVLSQKT 9
           SSSV SQKT
Sbjct: 94  SSSVPSQKT 102
>NP_001263624
          Length = 307

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SSSVLSQKT 9
          SSSV SQKT
Sbjct: 55 SSSVPSQKT 63
>NP_001018121
          Length = 558

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SSSVLSQKT 9
           +SSV+SQ+T
Sbjct: 268 ASSVISQRT 276
>NP_001136113
          Length = 1045

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SSSVLSQK 8
           S+S+LSQK
Sbjct: 580 SASILSQK 587
>NP_005388
          Length = 526

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SSVLSQKT 9
           SSV+SQ+T
Sbjct: 237 SSVISQRT 244
>NP_001129575
          Length = 1108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SSSVLSQKT 9
           S S+L++KT
Sbjct: 649 SDSILAEKT 657
>NP_733751
          Length = 4911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SSSVLSQK 8
            SSS+L+QK
Sbjct: 3786 SSSLLNQK 3793
>NP_001273148
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SSSVLSQKT 9
           S S+L++KT
Sbjct: 151 SDSILAEKT 159
>NP_001123885
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3 SVLSQKT 9
         +VLSQKT
Sbjct: 3 AVLSQKT 9
>NP_443139
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SSSVLSQKT 9
           S S+L++KT
Sbjct: 639 SDSILAEKT 647
>XP_006719284
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SSSVLSQKT 9
           S S+L++KT
Sbjct: 237 SDSILAEKT 245
>XP_006719283
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SSSVLSQKT 9
           S S+L++KT
Sbjct: 529 SDSILAEKT 537
>XP_006719282
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SSSVLSQKT 9
           S S+L++KT
Sbjct: 529 SDSILAEKT 537
>XP_006716142
          Length = 4927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SSSVLSQK 8
            SSS+L+QK
Sbjct: 3803 SSSLLNQK 3810
>XP_005250088
          Length = 4928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SSSVLSQK 8
            SSS+L+QK
Sbjct: 3803 SSSLLNQK 3810
>XP_006716141
          Length = 4959

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SSSVLSQK 8
            SSS+L+QK
Sbjct: 3803 SSSLLNQK 3810
>XP_005250085
          Length = 4979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SSSVLSQK 8
            SSS+L+QK
Sbjct: 3803 SSSLLNQK 3810
>XP_006716140
          Length = 4982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SSSVLSQK 8
            SSS+L+QK
Sbjct: 3803 SSSLLNQK 3810
>XP_005250084
          Length = 4982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SSSVLSQK 8
            SSS+L+QK
Sbjct: 3803 SSSLLNQK 3810
>XP_005250083
          Length = 4982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SSSVLSQK 8
            SSS+L+QK
Sbjct: 3802 SSSLLNQK 3809
>XP_005250082
          Length = 4983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SSSVLSQK 8
            SSS+L+QK
Sbjct: 3803 SSSLLNQK 3810
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.277   0.0896    0.179 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 351,354
Number of extensions: 520
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.7 bits)
S2: 28 (15.4 bits)

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