Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           18    1482
NP_004561                                                              18    1482
XP_005253450                                                           18    1482
XP_006719151                                                           18    1482
NP_852125                                                              16    5631
XP_006710661                                                           16    5631
XP_006710659                                                           16    5631
XP_006710658                                                           16    5631
XP_006710657                                                           16    5631
XP_005264049                                                           16    7355
XP_006712694                                                           16    7355
XP_006712693                                                           16    7355
XP_005264045                                                           16    7355
XP_005264042                                                           16    7355
XP_005264038                                                           16    7355
XP_006712692                                                           16    7355
XP_005264037                                                           16    7355
XP_006722357                                                           15    9605
>NP_001275701
          Length = 1486

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SSSQVSLSF 9
          SSSQVSL F
Sbjct: 32 SSSQVSLGF 40
>NP_004561
          Length = 1445

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SSSQVSLSF 9
          SSSQVSL F
Sbjct: 32 SSSQVSLGF 40
>XP_005253450
          Length = 1486

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SSSQVSLSF 9
          SSSQVSL F
Sbjct: 32 SSSQVSLGF 40
>XP_006719151
          Length = 1486

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SSSQVSLSF 9
          SSSQVSL F
Sbjct: 32 SSSQVSLGF 40
>NP_852125
          Length = 407

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSQVSLSF 9
           SSQ+SL F
Sbjct: 397 SSQISLGF 404
>XP_006710661
          Length = 4057

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SSSQVSLSF 9
            SSS  SLSF
Sbjct: 1549 SSSSASLSF 1557
>XP_006710659
          Length = 4556

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SSSQVSLSF 9
            SSS  SLSF
Sbjct: 1525 SSSSASLSF 1533
>XP_006710658
          Length = 4563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SSSQVSLSF 9
            SSS  SLSF
Sbjct: 1532 SSSSASLSF 1540
>XP_006710657
          Length = 4579

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SSSQVSLSF 9
            SSS  SLSF
Sbjct: 1548 SSSSASLSF 1556
>XP_005264049
          Length = 712

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SSSQVSL 7
           SSSQVSL
Sbjct: 689 SSSQVSL 695
>XP_006712694
          Length = 805

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SSSQVSL 7
           SSSQVSL
Sbjct: 782 SSSQVSL 788
>XP_006712693
          Length = 831

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SSSQVSL 7
           SSSQVSL
Sbjct: 808 SSSQVSL 814
>XP_005264045
          Length = 831

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SSSQVSL 7
           SSSQVSL
Sbjct: 808 SSSQVSL 814
>XP_005264042
          Length = 892

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SSSQVSL 7
           SSSQVSL
Sbjct: 869 SSSQVSL 875
>XP_005264038
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SSSQVSL 7
           SSSQVSL
Sbjct: 895 SSSQVSL 901
>XP_006712692
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SSSQVSL 7
           SSSQVSL
Sbjct: 895 SSSQVSL 901
>XP_005264037
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SSSQVSL 7
           SSSQVSL
Sbjct: 895 SSSQVSL 901
>XP_006722357
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SSSQVSLSF 9
          S  QVSLSF
Sbjct: 52 SFPQVSLSF 60
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.296    0.102    0.217 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 262,332
Number of extensions: 417
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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