Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001269329                                                           18    1935
NP_001011657                                                           18    1935
NP_001269330                                                           18    1935
XP_006724775                                                           18    1935
XP_006724774                                                           18    1935
XP_005262273                                                           18    1935
XP_005262271                                                           18    1935
XP_006724773                                                           18    1935
XP_005262270                                                           18    1935
XP_005262269                                                           18    1935
NP_001273575                                                           16    5631
NP_001073900                                                           16    5631
NP_001273577                                                           16    5631
NP_060520                                                              16    5631
XP_006716668                                                           16    5631
XP_006716667                                                           16    5631
XP_006711412                                                           16    5631
NP_009049                                                              16    7355
NP_065802                                                              16    7355
NP_001138551                                                           16    7355
NP_001127911                                                           16    7355
NP_001127910                                                           16    7355
NP_665696                                                              16    7355
XP_006714558                                                           16    7355
NP_001127909                                                           16    7355
NP_001025147                                                           15    9605
NP_008889                                                              15    9605
NP_001273171                                                           15    9605
NP_006302                                                              15    9605
NP_001511                                                              15    9605
NP_064509                                                              15    9605
NP_055268                                                              15    9605
NP_940818                                                              15    9605
NP_996806                                                              15    9605
NP_002067                                                              15    9605
NP_689412                                                              15    9605
NP_689410                                                              15    9605
NP_006231                                                              15    9605
NP_003984                                                              15    9605
XP_005276801                                                           15    9605
XP_005276799                                                           15    9605
XP_005274610                                                           15    9605
XP_005258804                                                           15    9605
XP_005258803                                                           15    9605
XP_005256932                                                           15    9605
XP_006721667                                                           15    9605
XP_005256931                                                           15    9605
XP_005256930                                                           15    9605
XP_006721666                                                           15    9605
XP_005256929                                                           15    9605
XP_005256928                                                           15    9605
XP_006721665                                                           15    9605
XP_005256925                                                           15    9605
XP_005256924                                                           15    9605
XP_006721664                                                           15    9605
XP_005256923                                                           15    9605
XP_006721105                                                           15    9605
XP_006720210                                                           15    9605
XP_005267700                                                           15    9605
XP_005267699                                                           15    9605
XP_005267698                                                           15    9605
XP_006720209                                                           15    9605
XP_005272398                                                           15    9605
XP_005244935                                                           15    9605
XP_005244933                                                           15    9605
>NP_001269329
          Length = 467

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  SSLRTRRY 9
          SSL TRRY
Sbjct: 77 SSLETRRY 84
>NP_001011657
          Length = 638

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SSLRTRRY 9
           SSL TRRY
Sbjct: 248 SSLETRRY 255
>NP_001269330
          Length = 467

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  SSLRTRRY 9
          SSL TRRY
Sbjct: 77 SSLETRRY 84
>XP_006724775
          Length = 450

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  SSLRTRRY 9
          SSL TRRY
Sbjct: 60 SSLETRRY 67
>XP_006724774
          Length = 467

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  SSLRTRRY 9
          SSL TRRY
Sbjct: 77 SSLETRRY 84
>XP_005262273
          Length = 598

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SSLRTRRY 9
           SSL TRRY
Sbjct: 208 SSLETRRY 215
>XP_005262271
          Length = 695

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SSLRTRRY 9
           SSL TRRY
Sbjct: 305 SSLETRRY 312
>XP_006724773
          Length = 699

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SSLRTRRY 9
           SSL TRRY
Sbjct: 309 SSLETRRY 316
>XP_005262270
          Length = 717

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SSLRTRRY 9
           SSL TRRY
Sbjct: 327 SSLETRRY 334
>XP_005262269
          Length = 718

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SSLRTRRY 9
           SSL TRRY
Sbjct: 328 SSLETRRY 335
>NP_001273575
          Length = 808

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSLRTRRY 9
           SSS+R RR+
Sbjct: 409 SSSMRRRRH 417
>NP_001073900
          Length = 798

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSLRTRRY 9
           SSS+R RR+
Sbjct: 358 SSSMRRRRH 366
>NP_001273577
          Length = 717

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSLRTRRY 9
           SSS+R RR+
Sbjct: 358 SSSMRRRRH 366
>NP_060520
          Length = 431

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSSLRTRRY 9
           S SLR +RY
Sbjct: 409 SESLRRKRY 417
>XP_006716668
          Length = 656

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSLRTRRY 9
           SSS+R RR+
Sbjct: 216 SSSMRRRRH 224
>XP_006716667
          Length = 768

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSLRTRRY 9
           SSS+R RR+
Sbjct: 409 SSSMRRRRH 417
>XP_006711412
          Length = 636

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  SSSLRTRR 8
          SSS RTRR
Sbjct: 39 SSSQRTRR 46
>NP_009049
          Length = 3097

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSSLRTRRY 9
            SSSL+ R Y
Sbjct: 1964 SSSLKRRHY 1972
>NP_065802
          Length = 657

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  SSLRTRR 8
          +SLRTRR
Sbjct: 67 NSLRTRR 73
>NP_001138551
          Length = 615

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  SSLRTRR 8
          +SLRTRR
Sbjct: 67 NSLRTRR 73
>NP_001127911
          Length = 1253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SLRTRRY 9
           +LRTR+Y
Sbjct: 235 NLRTRKY 241
>NP_001127910
          Length = 1253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SLRTRRY 9
           +LRTR+Y
Sbjct: 235 NLRTRKY 241
>NP_665696
          Length = 1210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SLRTRRY 9
           +LRTR+Y
Sbjct: 235 NLRTRKY 241
>XP_006714558
          Length = 2612

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSSLRTRRY 9
            SSSL+ R Y
Sbjct: 1479 SSSLKRRHY 1487
>NP_001127909
          Length = 1237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SLRTRRY 9
           +LRTR+Y
Sbjct: 262 NLRTRKY 268
>NP_001025147
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3 SLRTRR 8
         SLRTRR
Sbjct: 3 SLRTRR 8
>NP_008889
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3 SLRTRR 8
         SLRTRR
Sbjct: 3 SLRTRR 8
>NP_001273171
          Length = 2084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSLRTRRY 9
           SSSL+T R+
Sbjct: 593 SSSLKTGRH 601
>NP_006302
          Length = 2440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSSLRTRRY 9
            SSSL + RY
Sbjct: 1958 SSSLSSHRY 1966
>NP_001511
          Length = 2109

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSLRTRRY 9
           SSSL+T R+
Sbjct: 593 SSSLKTGRH 601
>NP_064509
          Length = 207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SSLRTRRY 9
           SSL  RRY
Sbjct: 158 SSLELRRY 165
>NP_055268
          Length = 222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LRTRRY 9
          +RTRRY
Sbjct: 67 VRTRRY 72
>NP_940818
          Length = 222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LRTRRY 9
          +RTRRY
Sbjct: 67 VRTRRY 72
>NP_996806
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSLRTRRY 9
           SSSL TR++
Sbjct: 161 SSSLGTRKW 169
>NP_002067
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SLRTRRY 9
           S+RTRR+
Sbjct: 541 SVRTRRF 547
>NP_689412
          Length = 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SSSLRTRR 8
          SSS +TRR
Sbjct: 5  SSSTKTRR 12
>NP_689410
          Length = 625

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SSSLRTRR 8
          SSS +TRR
Sbjct: 5  SSSTKTRR 12
>NP_006231
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SSSLRTRR 8
          SSS +TRR
Sbjct: 5  SSSTKTRR 12
>NP_003984
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  SSSLRTRR 8
          SSS RTRR
Sbjct: 37 SSSDRTRR 44
>XP_005276801
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  SSSLRTRR 8
          SSS RTRR
Sbjct: 37 SSSDRTRR 44
>XP_005276799
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  SSSLRTRR 8
          SSS RTRR
Sbjct: 37 SSSDRTRR 44
>XP_005274610
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SSSLRTRR 8
          SSS +TRR
Sbjct: 5  SSSTKTRR 12
>XP_005258804
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LRTRRY 9
          +RTRRY
Sbjct: 67 VRTRRY 72
>XP_005258803
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LRTRRY 9
          +RTRRY
Sbjct: 67 VRTRRY 72
>XP_005256932
          Length = 2448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSSLRTRRY 9
            SSSL + RY
Sbjct: 1966 SSSLSSHRY 1974
>XP_006721667
          Length = 2456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSSLRTRRY 9
            SSSL + RY
Sbjct: 1974 SSSLSSHRY 1982
>XP_005256931
          Length = 2466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSSLRTRRY 9
            SSSL + RY
Sbjct: 1984 SSSLSSHRY 1992
>XP_005256930
          Length = 2508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSSLRTRRY 9
            SSSL + RY
Sbjct: 2026 SSSLSSHRY 2034
>XP_006721666
          Length = 2511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSSLRTRRY 9
            SSSL + RY
Sbjct: 2042 SSSLSSHRY 2050
>XP_005256929
          Length = 2514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSSLRTRRY 9
            SSSL + RY
Sbjct: 2032 SSSLSSHRY 2040
>XP_005256928
          Length = 2515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSSLRTRRY 9
            SSSL + RY
Sbjct: 2033 SSSLSSHRY 2041
>XP_006721665
          Length = 2523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSSLRTRRY 9
            SSSL + RY
Sbjct: 2041 SSSLSSHRY 2049
>XP_005256925
          Length = 2523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSSLRTRRY 9
            SSSL + RY
Sbjct: 2041 SSSLSSHRY 2049
>XP_005256924
          Length = 2524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSSLRTRRY 9
            SSSL + RY
Sbjct: 2042 SSSLSSHRY 2050
>XP_006721664
          Length = 2524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSSLRTRRY 9
            SSSL + RY
Sbjct: 2042 SSSLSSHRY 2050
>XP_005256923
          Length = 2524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSSLRTRRY 9
            SSSL + RY
Sbjct: 2042 SSSLSSHRY 2050
>XP_006721105
          Length = 2046

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSLRTRRY 9
           SSSL+T R+
Sbjct: 593 SSSLKTGRH 601
>XP_006720210
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSSLRTRRY 9
           SSS + RRY
Sbjct: 279 SSSQKQRRY 287
>XP_005267700
          Length = 643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSSLRTRRY 9
           SSS + RRY
Sbjct: 410 SSSQKQRRY 418
>XP_005267699
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSSLRTRRY 9
           SSS + RRY
Sbjct: 394 SSSQKQRRY 402
>XP_005267698
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSSLRTRRY 9
           SSS + RRY
Sbjct: 410 SSSQKQRRY 418
>XP_006720209
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSSLRTRRY 9
           SSS + RRY
Sbjct: 396 SSSQKQRRY 404
>XP_005272398
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3 SLRTRR 8
         SLRTRR
Sbjct: 3 SLRTRR 8
>XP_005244935
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  SSSLRTRR 8
          SSS RTRR
Sbjct: 37 SSSDRTRR 44
>XP_005244933
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  SSSLRTRR 8
          SSS RTRR
Sbjct: 37 SSSDRTRR 44
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.119    0.302 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 375,124
Number of extensions: 637
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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