Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004324                                                              18    1135
XP_005250103                                                           18    1135
XP_005250102                                                           18    1135
NP_659410                                                              17    3301
XP_006719103                                                           17    3301
XP_005253384                                                           17    3301
XP_005253383                                                           17    3301
NP_055365                                                              16    5631
NP_055186                                                              16    7355
NP_787036                                                              16    7355
NP_787034                                                              16    7355
NP_787033                                                              16    7355
NP_001257620                                                           16    7355
XP_006723641                                                           16    7355
NP_001035194                                                           16    7355
NP_000746                                                              15    9605
NP_001244292                                                           15    9605
NP_110436                                                              15    9605
XP_006719684                                                           15    9605
XP_005251766                                                           15    9605
XP_005251765                                                           15    9605
XP_005251764                                                           15    9605
XP_005251763                                                           15    9605
XP_005265997                                                           15    9605
>NP_004324
          Length = 766

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SSSASMDSV 9
           SSSASMD+V
Sbjct: 112 SSSASMDTV 120
>XP_005250103
          Length = 758

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SSSASMDSV 9
           SSSASMD+V
Sbjct: 112 SSSASMDTV 120
>XP_005250102
          Length = 767

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SSSASMDSV 9
           SSSASMD+V
Sbjct: 112 SSSASMDTV 120
>NP_659410
          Length = 1274

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSSASMDSV 9
           SSS SMDS+
Sbjct: 150 SSSCSMDSL 158
>XP_006719103
          Length = 1296

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSSASMDSV 9
           SSS SMDS+
Sbjct: 172 SSSCSMDSL 180
>XP_005253384
          Length = 1311

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSSASMDSV 9
           SSS SMDS+
Sbjct: 150 SSSCSMDSL 158
>XP_005253383
          Length = 1333

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSSASMDSV 9
           SSS SMDS+
Sbjct: 172 SSSCSMDSL 180
>NP_055365
          Length = 1032

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSSASMDSV 9
           SSS+S DSV
Sbjct: 567 SSSSSSDSV 575
>NP_055186
          Length = 646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SSSASMDSV 9
          S SAS DSV
Sbjct: 83 SGSASADSV 91
>NP_787036
          Length = 532

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSSASMDSV 9
           SSS SMD V
Sbjct: 209 SSSHSMDEV 217
>NP_787034
          Length = 502

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSSASMDSV 9
           SSS SMD V
Sbjct: 209 SSSHSMDEV 217
>NP_787033
          Length = 555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSSASMDSV 9
           SSS SMD V
Sbjct: 209 SSSHSMDEV 217
>NP_001257620
          Length = 585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSSASMDSV 9
           SSS SMD V
Sbjct: 209 SSSHSMDEV 217
>XP_006723641
          Length = 555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSSASMDSV 9
           SSS SMD V
Sbjct: 209 SSSHSMDEV 217
>NP_001035194
          Length = 4493

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SSSASMDS 8
            SSSA++DS
Sbjct: 3733 SSSATLDS 3740
>NP_000746
          Length = 626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SASMDSV 9
           SASMDS+
Sbjct: 470 SASMDSL 476
>NP_001244292
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SASMDSV 9
           SASMDS+
Sbjct: 449 SASMDSL 455
>NP_110436
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SSASMDS 8
           SSAS+DS
Sbjct: 345 SSASLDS 351
>XP_006719684
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SSASMDS 8
           SSAS+DS
Sbjct: 345 SSASLDS 351
>XP_005251766
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SASMDSV 9
           SASMDS+
Sbjct: 449 SASMDSL 455
>XP_005251765
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SASMDSV 9
           SASMDS+
Sbjct: 449 SASMDSL 455
>XP_005251764
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SASMDSV 9
           SASMDS+
Sbjct: 466 SASMDSL 472
>XP_005251763
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SASMDSV 9
           SASMDS+
Sbjct: 471 SASMDSL 477
>XP_005265997
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SSSASMDSV 9
          SSSA+ D+V
Sbjct: 13 SSSAAFDTV 21
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.274   0.0837    0.168 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 354,372
Number of extensions: 441
Number of successful extensions: 24
Number of sequences better than 10000.0: 24
Number of HSP's gapped: 24
Number of HSP's successfully gapped: 24
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.6 bits)
S2: 28 (15.4 bits)

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