Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              17    3301
XP_006716142                                                           17    3301
XP_005250088                                                           17    3301
XP_006716141                                                           17    3301
XP_005250085                                                           17    3301
XP_006716140                                                           17    3301
XP_005250084                                                           17    3301
XP_005250083                                                           17    3301
XP_005250082                                                           17    3301
NP_056080                                                              16    7355
NP_001165980                                                           16    7355
NP_001165988                                                           16    7355
XP_005246453                                                           16    7355
XP_006712435                                                           16    7355
NP_079510                                                              15    9605
NP_055665                                                              15    9605
NP_001028289                                                           15    9605
XP_006726390                                                           15    9605
XP_006726389                                                           15    9605
XP_006726388                                                           15    9605
XP_006726387                                                           15    9605
XP_005254755                                                           15    9605
XP_006713496                                                           15    9605
XP_006713122                                                           15    9605
XP_006713118                                                           15    9605
XP_006713117                                                           15    9605
XP_006713114                                                           15    9605
XP_006713110                                                           15    9605
XP_006713109                                                           15    9605
XP_006713108                                                           15    9605
XP_006713107                                                           15    9605
XP_006713106                                                           15    9605
XP_006713102                                                           15    9605
XP_006713101                                                           15    9605
XP_006713100                                                           15    9605
XP_006713099                                                           15    9605
XP_006711142                                                           15    9605
XP_006711141                                                           15    9605
XP_006711140                                                           15    9605
XP_006710131                                                           15    9605
XP_006710130                                                           15    9605
XP_006710129                                                           15    9605
XP_006710128                                                           15    9605
>NP_733751
          Length = 4911

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSSAD SKA
Sbjct: 771 SSSADISKA 779
>XP_006716142
          Length = 4927

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSSAD SKA
Sbjct: 772 SSSADISKA 780
>XP_005250088
          Length = 4928

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSSAD SKA
Sbjct: 772 SSSADISKA 780
>XP_006716141
          Length = 4959

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSSAD SKA
Sbjct: 772 SSSADISKA 780
>XP_005250085
          Length = 4979

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSSAD SKA
Sbjct: 772 SSSADISKA 780
>XP_006716140
          Length = 4982

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSSAD SKA
Sbjct: 772 SSSADISKA 780
>XP_005250084
          Length = 4982

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSSAD SKA
Sbjct: 772 SSSADISKA 780
>XP_005250083
          Length = 4982

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSSAD SKA
Sbjct: 771 SSSADISKA 779
>XP_005250082
          Length = 4983

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSSAD SKA
Sbjct: 772 SSSADISKA 780
>NP_056080
          Length = 733

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SADKSKA 9
           +ADKSKA
Sbjct: 719 NADKSKA 725
>NP_001165980
          Length = 733

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SADKSKA 9
           +ADKSKA
Sbjct: 719 NADKSKA 725
>NP_001165988
          Length = 733

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SADKSKA 9
           +ADKSKA
Sbjct: 719 NADKSKA 725
>XP_005246453
          Length = 675

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SADKSKA 9
           +ADKSKA
Sbjct: 661 NADKSKA 667
>XP_006712435
          Length = 733

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SADKSKA 9
           +ADKSKA
Sbjct: 719 NADKSKA 725
>NP_079510
          Length = 305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SSSADKS 7
           SSS+DKS
Sbjct: 249 SSSSDKS 255
>NP_055665
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SSSADKS 7
            +SSADKS
Sbjct: 1090 NSSADKS 1096
>NP_001028289
          Length = 1075

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SSSADKS 7
            +SSADKS
Sbjct: 1066 NSSADKS 1072
>XP_006726390
          Length = 1353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           +SSA K+KA
Sbjct: 428 ASSASKNKA 436
>XP_006726389
          Length = 1471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           +SSA K+KA
Sbjct: 428 ASSASKNKA 436
>XP_006726388
          Length = 1489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           +SSA K+KA
Sbjct: 428 ASSASKNKA 436
>XP_006726387
          Length = 1497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           +SSA K+KA
Sbjct: 428 ASSASKNKA 436
>XP_005254755
          Length = 305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SSSADKS 7
           SSS+DKS
Sbjct: 249 SSSSDKS 255
>XP_006713496
          Length = 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SSSADKS 7
           +SSADKS
Sbjct: 582 NSSADKS 588
>XP_006713122
          Length = 1062

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSS DK++A
Sbjct: 692 SSSPDKNEA 700
>XP_006713118
          Length = 1328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSS DK++A
Sbjct: 458 SSSPDKNEA 466
>XP_006713117
          Length = 1334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSS DK++A
Sbjct: 464 SSSPDKNEA 472
>XP_006713114
          Length = 1523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSS DK++A
Sbjct: 692 SSSPDKNEA 700
>XP_006713110
          Length = 1533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSS DK++A
Sbjct: 692 SSSPDKNEA 700
>XP_006713109
          Length = 1537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSS DK++A
Sbjct: 692 SSSPDKNEA 700
>XP_006713108
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSS DK++A
Sbjct: 692 SSSPDKNEA 700
>XP_006713107
          Length = 1544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSS DK++A
Sbjct: 692 SSSPDKNEA 700
>XP_006713106
          Length = 1545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSS DK++A
Sbjct: 692 SSSPDKNEA 700
>XP_006713102
          Length = 1554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSS DK++A
Sbjct: 692 SSSPDKNEA 700
>XP_006713101
          Length = 1561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSS DK++A
Sbjct: 692 SSSPDKNEA 700
>XP_006713100
          Length = 1561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSS DK++A
Sbjct: 691 SSSPDKNEA 699
>XP_006713099
          Length = 1562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           SSS DK++A
Sbjct: 692 SSSPDKNEA 700
>XP_006711142
          Length = 1471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           +SSA K+KA
Sbjct: 428 ASSASKNKA 436
>XP_006711141
          Length = 1489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           +SSA K+KA
Sbjct: 428 ASSASKNKA 436
>XP_006711140
          Length = 1497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           +SSA K+KA
Sbjct: 428 ASSASKNKA 436
>XP_006710131
          Length = 1353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           +SSA K+KA
Sbjct: 428 ASSASKNKA 436
>XP_006710130
          Length = 1471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           +SSA K+KA
Sbjct: 428 ASSASKNKA 436
>XP_006710129
          Length = 1489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           +SSA K+KA
Sbjct: 428 ASSASKNKA 436
>XP_006710128
          Length = 1497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSSADKSKA 9
           +SSA K+KA
Sbjct: 428 ASSASKNKA 436
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.263   0.0795    0.161 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 417,124
Number of extensions: 418
Number of successful extensions: 43
Number of sequences better than 10000.0: 43
Number of HSP's gapped: 43
Number of HSP's successfully gapped: 43
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 19 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.3 bits)
S2: 28 (15.4 bits)

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